[Objective]The relationship of inheritance and innovation is one of most important problems of TCM.Wind of historyis a historical theory pro-posed by Liu Xianxin. We use the theory to analyze the inheritance and innovation in the history of TCM, so that we can identify the relationship of inheri-tance and innovation of TCM under current background. [Methods]Based onWind of historytheory, we try to analyze classic innovated case in the history of TCM.After that, we analyze the current relationship and controversy of inheritance and innovation of TCM. [Results]We find that al innovation comes from the interaction of inheritance and the Wind of history. Different innovation comes from the interaction of different problems and different wind. [Conclusions]We need not make innovation as the purpose or requirements imposed on TCM. If we have better inheritance, innovation is just there when we confront new problem.

Objective To explore the effect of the H-uvulopalatopharyngology(H-UPPP)on the obstructive sleep apnea hypopnea syndrome(OSAHS)with hypertension sufferers.Methods The clinical data of 100 cases of OSAHS patients with hypertension were analyzed retrospectively,and the related parameters about changes of blood pressure and respiration were analyzed.Results The sargical operation treatment cure rate of OSAHS eas 37%,and the effective rate was 81%.In those patients.all the hypertension patients who in the first stage were completely cured (46/46),while for whom in the second stage,the cure rate was 37%(13/35).So the total effective rate of experimental group Was 88%(30/35).19 cases was ineffective.In those 19 patients,there were 16 patients in the second stage,while 3 cases in the third stage.Conclusion H-UPPP could completely cure OSAHS,meanwhile,it also obviously lowered hypertension which induced by OSAHS,and made the sufferers keep at relative normal blood pressure for a long time.So H-UPPP Was a best treatment method to the OSAHS patients with hypertension.

Objective To observe the effect of Huanyuan Injection on TNF－ α 、 sIL－ 2R in patients with acute Intracranial hemorrhage.Method Sixty patients were randomly selected and divided into two groups.TNF－ α 、 sIL－ 2R in the blood of the patients were observed before and after therapy with Huanyuan Injection.Result Increasing level of TNF－ α 、 sIL－ 2R could be detected,at the same time,Huayuan Injection could react on the differentiation.Conclusion The effect of Hyanyuan Injection on the levels of TNF－ α 、 sIL－ 2R may show some insight on its therapeutic mechanism for acute hemorrhage stroke.

[Objective] Analyze the discussion of Qi and Qi transformation in Huangdi Neijing, therefore to give insight into the Qi Theory of TCM. [Methods] Analyze articles about Qi and Qi transformation in Huangdi Neijing, as well as comments from doctors of all dynasties, to summerize the understanding on Qi and Qi transformation of Huangdi Neijin. [Result] In the whole book of Huangdi Neijing, there are 19 chapters named after Qi, 1700 (2997) characters of Qi are mentioned, and there are 7 discussions upon Qi transformation. The Qi mentioned in Huangdi Neijing can be material, or functional, or be able to transform. The conception of Qi transformation includes six parts: the transformation among Yin and Yang, among the five elements, and the growth and transformation among all kinds of essences, the transportation, nutrition and transformation among all kinds of matters, as well as the transportation of Qi and the transformation of five elements' motion and six kinds of natural factors.[Conclusion] Qi transformation is mentioned in all but a few chapters in Huangdi Neijing. Everything, from matters growing to turning into essences is actually Qi transformation. In Huangdi Neijing's view, Qi transformation is the fundamental of all matters coming into being, and the fundamental to stay healthy, therefore the fundamental of preserving health, diagnosis and treatment.

Objective To study the impact of the high temperature and muggy weather on the people’s life and work. Methods The data of summer temperature and relative humidity (Jun-Aug) from 1971 to 2000 and that of 2006 were used and the characteristic of muggy weather and distribution in main cities, Chengdu, Guangyuan, Yibing, Suining and Dazhou in Sichuan basin were compared, the influence of the thermal environment on people comfort degree was evaluated by using temperature-humidity index. Results 177 high temperature days, 17 high temperature processes, 167 muggy weather days and 12 muggy processes were seen in 5 cities in Sichuan basin in the summer of 2006. The thermal environment of Chengdu and Dazhou mainly manifested the lighter heat, heat and lower comfort degree. At 2 p.m., the relative humidity weakened the comfort degree in Chengdu, but enhanced it in Dazhou. The duration of non-comfort degree in Dazhou was longer than that in Chengdu. Conclusion The relative humidity has a strong impact on people comfort degree and the combined use of temperature and relative humidity will be useful to evaluate the city thermal environment and people comfort degree.

OBJECTIVE:To observe the curative efficacy of compound glycyrrhizin in the treatment of chronic type B hepatitis.METHODS:102patients with type B hepatitis were randomly selected to receive compound glycyrrhizin60ml by in-travenous drip infusion once daily for30days.The clinical symptoms,signs,and indexes of hepatic function and hepatic fibrosis were observed before and after treatment.RESULTS:As compared with treatment before,patients’symptoms,signs,indexes of hepatic function and hepatic fibrosis all had obvious amelioration after treatment(P

Cardiomyopathy, Dilated ; genetics ; Lamin Type A ; genetics

In addition to kill tumor cells through direct cytotoxicity, the immunomodulatory activity is another facet of chemotherapy. The major molecular mechanisms of immunogenicity of cytotoxic drugs are elimination of CD_4~+ CD_(25)~+ regulatory T cells or Myeloid-Derived Suppressor Cells, and sensitization of tumor cells to immune effectors through modulation of death receptor expression. These studies provide scientific evidence for combinatorial treatments including vaccines and Traditional Chinese Medicine for cancer therapy.

Objective] The article analyzed the application of qi transformation for diagnosis and treatment in clinic from four aspects: theory, method, formula and herbs. [Methods] Wang Kungen is instructor of the fourth,fifth project of academic experience inheriting the old Chinese medicine experts. Director Wang believes that the Qi transformation is the fundamental of everythings,including the humanbody.To analyze the relationship between qi transformation and theory-method-formula-herbs in clinical TCM based on the study of Huangdi Neijing and textual works of famous Chinese physicians. [Result]Qi transformation is the foundation of life, therefore the foundation of health. Abnormal Qi transformation leads to process and development of diseases, so the key to the treatment is to achieve the condition of“seizing the mechanism of disease and keeping qi in harmony”through all methods, rather than holding on to specific treatments like acupuncture and herbs. [Conclusion]Qi transformation is not only an important content of TCM theory system, but also the key point of treatment in clinic, and the core clinical theory of Director Wang.

Objective To compare the solution rate of berberine in Gegen Qinlian decoction and Chinese goldthread decoction,to clarify the scientific nature of the traditional Chinese medicine compound.Methods High performance liquid chromatography(HPLC)was used to detect the content of berberine in Gegen Qinlian decoction and Chinese goldthread decoction.Chromatographic condition was C1 8 chromatographic column,mobile phase was acetonitrile:0.05mol/L of potassium dihydrogen phosphate(48:52)(0.4g sodium dodecyl sulfate was added to per 1 00mL solution,adjusted pH to 4.0 with glacial acetic acid),detection wavelength was 345nm,the sample size was 1 0μL,flow rate was 1 .0mL/min,column temperature was 30℃.Results The average decoct rate of berberine in Gegen Qinlian decoction was 0.73%,while that was 0.45% in Chinese goldthread decoction,there was significant difference between the two groups(P <0.01 ).Conclusion The efficacy of TCMcompound Gegen Qinlian decoction is greater than the efficacy of the unilateral simple accumulation,so traditional Chinese medicine compound has certain scientific nature.