1.Analysis of application of clinical nursing pathway in maintenance hemodialysis patients
Chinese Journal of Practical Nursing 2013;(10):36-38
Objective To explore the application effect of clinical nursing pathway on maintenance hemodialysis patients.Methods Totally 120 patients with maintenance hemodialysis between January 1 and December 31 2009 were randomly assigned to the control group and the observation group with 60 patients in each group.The clinical pathway was established and applied to the observation group.The treatment effect was compared between two groups.Results The incidence of complications and nursing errors declined with the application of clinical nursing pathway,and the doctor's orders compliance and the satisfaction and quality of care were improved significantly.Conelusions The application of clinical nursing pathway in maintenance hemodialysis patients is an effective method for improving overall care quality and the satisfaction degree of the patients with nursing,so as to improve their survival rate.
2.Development of catheter ablation in children with tachycardia
Chinese Journal of Applied Clinical Pediatrics 2017;32(13):965-968
With a high success and low recurrence,catheter ablation has become the standard of cure in children with tachycardia.With the innovation of mapping ablation techniques,catheter ablation for children with tachycardia has been developed.In this review, green cardiac electrophysiology,complex arrhythmias ablation with electroanatomic mapping systems and cryoablation in children will be discussed.
3.Endostar inhibits proliferation and cell functions of tumor-derived endothelial cells
Li JIANG ; Yong HE ; Yaoguang JIANG
Journal of Third Military Medical University 2003;0(21):-
Objective Tumor vessels were foundation of tumors’formation,growth and metastasis,and the destruction of a spot of them would lead to wide avascular necrosis of tumor cells,so the specific killing effect on tumor vasculature endothelial cells had become one of the most important strategies for tumor therapy. Endostar,a novel recombinant human endostatin expressed and purified with an additional nine-amino acid sequence,is a new anti-drug. This study aimed to determine how endostar to affect the behavior of endothelial cells and tumor endothelial cells in vitro and in vivo. Methods Human umbilical vein endothelial cells ( HUVEC) was isolated and cultured followed by identification with Ⅷ factor related antigens. The cells differentiated into tumor-derived endothelial cells ( Td-ECs) by co-culturing with supernatants of A549 cells. The anti-effect of endostar on Td-ECs was detected with MTT assay,cell migration assay,flow cytometry and TUNEL assay. Results Endostar had a significant effect on the proliferation of Td-EC in a time-and concentration-dependent manner. At the same time,though Endostar at a certain concentration inhibited cell migration process significantly,arrested the cells at G0 /G1 and S phases and induced cell apoptosis ( P 0. 05) . Conclusion Our study indicates a novel function of endostar,to inhibit and Td-ECs proliferation in vitro. So,using endostar for cancer therapy is worthwhile for further study in clinical trials.
4.Recent advances on EZH2 in malignant tumors.
Chinese Journal of Pathology 2009;38(12):856-858
Biomarkers, Tumor
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metabolism
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Breast Neoplasms
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metabolism
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DNA-Binding Proteins
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genetics
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metabolism
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Digestive System Neoplasms
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metabolism
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Enhancer of Zeste Homolog 2 Protein
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Female
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Gene Expression Regulation, Neoplastic
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Humans
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Lymphoma
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metabolism
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Polycomb Repressive Complex 2
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Prognosis
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RNA, Messenger
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metabolism
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Transcription Factors
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genetics
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metabolism
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Urogenital Neoplasms
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metabolism
5.Bacteriostatic Action of Yiqing Capsule against Propionibacterium Acnes and Staphylococcus Epidermidis in vitro
Xian JIANG ; Yan HE ; Li LI
China Pharmacy 2007;0(33):-
OBJECTIVE: To study the bacteriostatic action of Yiqing capsule against propionibacterium acnes and staphylococcus epidermidis in vitro.METHODS: Propionibacterium acnes and staphylococcus epidermidis were cultured by microplating method and routine plating,and the bacteriostatic action of different concentration of Yiqing capsule and its main components against propionibacterium acnes and staphylococcus epidermidis were determined by measuring their MICs.RESULTS: The MICs of Yiqing capsule and Scutellaria baicalensis extractum against propionibacterium acnes and staphylococcus epidermidis were 0.98 mg?mL-1 and 1 mg?mL-1,respectively,whereas the MICs of Radix et Rhizoma Rhei and Rhizoma Coptidis Scutellaria extractum against propionibacterium acnes and staphylococcus epidermidis were 1.96 mg?mL-1 and 1 mg?mL-1,respectively.CONCLUSION: Yiqing capsule showed satisfactory bacteriostatic action against the major pathogenic bacteria of acne.
6.Changes in body shape,heart rate and blood pressure of 76 elderly women after aerobic exercise for 24 weeks
Tao JIANG ; Jianmin LI ; Jin HE
Chinese Journal of Tissue Engineering Research 2007;0(17):-
To observe the effect of aerobic exercise on the body shape,cardiovascular,physiology and biochemical indexes of elderly women,we trained 76 old women (volunteers,mean age 58 years old) from urban area of Yulin from 14th July 2005 to 14th January 2006,60 minutes every time,3 times a week. The heart rate during exercise was controlled within 110-125 times per minute. The changes in their body shape (body mass and waistline),cardiovascular function (resting heart rate and blood pressure) and biochemical indexes before and after exercise were observed. The results showed that after 24 weeks of aerobic exercise,the body mass and waistline of the subjects were decreased compared with that before exercise (P
7.Analysis on distribution and drug resistance of carbapenem-resistant Acinetobacter baumannii infections
Lei HE ; Chunhua LI ; Daobin JIANG
Chongqing Medicine 2016;45(21):2966-2968,2972
Objective To investigate the distribution of carbapenem‐resistant Acinetobacter baumannii(CRAB) infections and its resistance to commonly used antibacterial drugs to provide a basis for infection control and rational use of antibacterial drugs in this area .Methods The clinical data and drug susceptibility test results in the patients with CRAB infection in our hospital from January 1 ,2013 to December 31 ,2014 were retrospectively analyzed .Results Eighteen strains of CRAB in community‐acquired in‐fection and 140 strains of CRAB in nosocomial infection were isolated ,the resistance rates to piperacillin/tazobactam ,gentamicin and tobramycin were higher than 80% ,which to ampicillin/sulbactam and levofloxacin were 64 .5% and 48 .2% respectively ,which to compound SMZ and amikacin were lower than 25% .The distribution of drug sensitivity results had no statistical difference between community CRAB infection and nosocomial CRAB infection (P>0 .05) .Conclusion The CRAB infection is mainly nosocomial in‐fection ,the empirical therapy could select compound SMZ and amikacin .
10.The preliminary report of the device and clinical application of continu ous and constant pressure skin expansion perfusion apparatus(CCPSEPA)
Zhongwen HE ; Biao WANG ; Jiang LI
Chinese Journal of Medical Aesthetics and Cosmetology 2001;7(2):69-71
Objective To search for a simple and rapid skin expansion. Methods CCPSEPA-A kind of mutual feedback type continuous normal saline perfusion system was assembled with the use of conventional transfusi on apparatus, sphygmomanometer, three-way stopcocks, plasma bag etc.14 cases ( 17 expanders) were carried out with such a device, controlled by patients themselves. Results The volume of expanders was 50~300 ml and the duration of expansion was 7~14 days. All the cases proved a wonderful effect that the expansion was finished by only one or two times of water filling of storage water bag, and without any complications.Conclusion CCPSEPA is a new skin expansion apparatus of new type and practical ,simple and low price .The general goal of safe,simple, rapid and useful was realized basically by the device,and worth popularizing.