OBJECTIVE:To establish the method for content determination of?-Schisandrin in Lingzhi granules.METH_ ODS:HPLC method was adopted and a C 18 column was used.The mobile phase was acetonitrile-0.1%H 3 PO 4 of water solution(67∶33).The detection wavelength was at254nm.RESULTS:The calibration curve of?-Schisandrin was linear in the range of0.0816?g～0.816?g(r=0.9999),and the average recovery was99.21%(RSD=0.79%).CONCLUSION:The method is simple and accurate,and can be used for the quality control of Lingzhi granule.

OBJECTIVE:To research how to successfully convert prescribed drug into OTC and to predict the conversion prospect.METHODS:Several prescribed drug-OTC conversion cases in some countries of the world were introduced and the reasons for success or failure were analyzed.RESULTS & CONCLUSIN:The strategy of successful conversion of prescribed drug into OTC is recommended.The conversion prospect depends on the future development trend of a series of factors.

OBJECTIVE: To provide referrences for the state drug administrations strengthening supervision and administration, and also for the pharmaceutical enterprises develeping drug marketing.METHODS: To explain the concept of DTC marketing.And the present situation of drug DTC marketing in several foreign countries were discussed and its development process and existing problems in these countries were also analyzed. RESULTS: Drug DTC marketing was under development in the world and pharmaceutical enterprises hawe showed increasing interest in it, however, drug DTC marketing needed further standardization and improvement. CONCLUSION: Drug DTC marketing holds a promising prospect, the effective and standardized development of it will be a big challenge to state drug administrations and pharmaceutical companies in the world.

0.05). The concentrations of MMP-2 and MMP-9 were significantly increased on days 1, 10, and 30 after percutaneous coronary intervention, and those on day 10 were higher than on day 1 (P

Adult ; Aged ; Female ; Herbicides ; poisoning ; Humans ; Male ; Middle Aged ; Paraquat ; poisoning ; Poisoning ; therapy ; Young Adult

Objective To evaluate the application value of magnetic resonance cholangiopancreatography (MRCP) in the pa‐tients suffering from obstructive jaundice .Methods 126 patients diagnosed as obstructive jaundice underwent the abdominal MRCP examination and MRI scanning .The diagnostic results were recorded and the follow‐up observation was persisted .The MRCP diag‐nosis results were compared with the pathological or ERCP results obtained by follow up .Results Comparing the MRCP diagnostic results with the follow up results ,the coincidence rate of location diagnosis was 100% .The MRCP and follow up results in the qual‐itative diagnosis had no statistically significant difference .M RCP had the higher sensitivity ,specificity ,positive value and negative value in the judgement of different causes of obstruction .Conclusion M RCP has the higher accuracy for the qualitative and location diagnosis of obstructive juandice and also has the higher diagnostic value for judging the different obstructive causes .

With continuous research of the formation mechanism of chronic pancreatitis with mass in the head of the pancreas and its relation with pancreatic cancer,and steady improvement of the operation safety,the number of operation for the chronic pancreatitis with mass in the head of the pancreas is increasing.On the other hand,with the improvement of the accuracy of preoperative diagnosis,Tru-cut intraoperative biopsy is increasingly applied to patients with negative results of preoperative ultrasonography biopsy,which is important for the surgical procedure selection.With the premise of effective treatment,continous improvement of treatment strategies to the chronic pancreatitis with mass in the head of the pancreas can maximize the benefit of patients.

Patellar instability is a common cause of knee pain and a common disease of patellofemoral joint.It is one of the important etiological factors of chondromalacia patella or patellofemoral joint osteoarthritis.This paper investigates the pathological mechanism,sympton,physical examination and photographic of patellar instability.And the results showed that correct diagnosis lead to reasonable treatment.The emphasis of therapy is to restore the balance of soft tissue around palella.Combined orthopedic treatment is commonly used according to different age,different instability degrees,and pathological factors of different patients.

[Objective]To investigate curative effect for thoracolumbar burst fractures by the method of vertebral pedicle screw fixation applied in the with transpedicular bone graft,and consider its indications.[Method]Thirty cases of thoracolumbar burst fractures were treated by vertebral pedicle screw fixation combining transpedicular bone graft.Among them 22 were male and 8 were famale,age ranged 18-64.All of cases were single segment fractures.The average height of anterior border was 35% before the operation,the average of Cobb's angle was 26?,the percentage of midsagital diameter was 55%.According to Frankel's neurological function classification,preoperative neurological function was Grade A in 4 cases,B in 8,C in 5,D in 6,E in 7.[Result]All cases were followed up for 6 to 30 months.All patients' pain relieved distinctly,the average height anterior border was increased to 97%,the average of Cobb's angle was 3.5?,the percentage of midsagital diameter was 92% postoperatively,showing significant difference(P