1.Clinical Features of Adult Attention-Deficit/Hyperactivity Disorder among Substance Abusers
Chinese Mental Health Journal 2002;0(09):-
Objective:To explore the clinical presentations and symptom distribution in adults with attention-deficit/hyperactivity disorder(ADHD) among non-alcohol substance use disorder population,and to prove the effectiveness of adult ADHD diagnosis.Methods:Thirty adults with ADHD and thirty non-ADHD controls were selected from Beijing Compulsory Detoxification Center,matched with sex,age,and education.Data collection included the following:(1)Self-report measures of developmental history,employment history,social history and ADHD clinical symptoms.(2)Psychiatric interview using structured assessments included the Clinical Diagonsitic Interview Scale(CDIS)for Diagnostic and Statistical Manual of Mental Disorders(DSM-IV).(3)Evaluation for cognitive function with the Wechsler Adult Intelligence Scale-Revised Chinese(WAIS-RC).Results:(1)The clinical core symptoms(such as attention deficit,restlessness,and impulsive symptoms)among adulthood ADHD were similar to childhood ADHD except for some hyperactivity symptoms.(2)The symptoms of attention deficit,restlessness and impulsiveness were more frequently in both of adulthood and childhood ADHD than non-ADHD controls(P
2.Bacterial Culture of Infant Eye Secretions and Drug Resistance Analysis
Jinlong DING ; Li YANG ; Qunhua YING
Chinese Journal of Nosocomiology 2009;0(23):-
OBJECTIVE To understand the pathogen distribution of infant infectious bacterial conjunctivitis and keratitis,and drug resistance to provide guidence on clinical treatment.METHODS The routine bacterial culture of eye secretions in the 331 cases was identified with K-B to determine the resistance of pathogenic bacteria.RESULTS A total of 124 strains were isolated with positive rate of 37.46%,there were Haemophilus parainfluenzae,Staphylococcus aureus,H.influenzae,S.epidermidis,fungi,etc.The resistance of S.aureus,S.epidermidis and S.pneumoniae to penicillin were 86.36%,88.89% and 0,respectively.The resistance rate of H.parainfluenzae,H.influenzae,Escherichia coli,Klebsiella pneumoniae and Pseudomonas aeruginosa to ampicillin were 12.50%,27.78%,87.50%,100.00% and 100.00%;that to cefazolin were 16.67%,16.67%,62.50%,14.29% and 100.00%;and to cotrimoxazole were 50.00%,27.78%,12.50%,14.29% and 100.00%.CONCLUSIONS The H.parainfluenzae,S.aureus,H.influenzaeand S.epidermidis are isolated from the newborn eye secretions;they were lower resistant to ofloxacin and ciprofloxacin.
3.Evaluation of left ventricular function by echocardiography in patients with acute myocardial infarction(AMI)by autologous peripheral blood stem cell transplantation
Ying LIU ; Zhanquan LI ; Mingyan DING
Chinese Journal of Practical Internal Medicine 2006;0(19):-
Objective To evaluate left ventricular function in patients with acute myocardial infarction(AMI)by autologous peripheral blood stem cells(PBSCs)transplantation with echocardiography.Methods Patients with AMI were randomly assigned to receive intracoronary PBSCs transplantation following bone marrow cells mobilization(standard drug therapy and PCI,PBSCs transplantation group,n=35)or only receive standard therapy(standard drug therapy and PCI,n=34).Echocardiography were performed before and 6 months after treatment.Results LV function was significantly improved 6 months after G-CSF mobilized autologous PBSCs transplantation compared to baseline(P
4.Studies on chemical constituents from Gerbera piloselloides
Ying XIAO ; Jianbei LI ; Yi DING ;
Chinese Traditional and Herbal Drugs 1994;0(02):-
Object To study the chemical constituents from the roots of Gerbera piloselloides Cass Methods The compounds were isolated using RA polystyrene resin and silica gel column chromatography, and the structures of these compounds were elucidated by means of spectral analysis Results Arbutin, daphnetin 8 O ? D glucopyranoside, 2, 6 dimethoxy 4 hydroxyphenol 1 O ? D glucopyranoside, koaburaside, glucosyringic acid, marmesinin were elucidated Conclusion Compounds Ⅱ Ⅵ were isolated from Gerbera L ex Cass for the first time
5.Optimization on Extraction Technology of Shu-Feng Ding-Chuan Granules in Huang-Qin Group by Box-Behnken Response Surface Methodology
Ruihua LI ; Ying LI ; Yongxiang WANG ; Yun WU ; Gang DING
World Science and Technology-Modernization of Traditional Chinese Medicine 2015;(11):2290-2295
This study was aimed to optimize the extraction technology of Shu-Feng Ding-Chuan(SFDC) granules in the Huang-Qin(HQ)group by Box-Behnken response surface methodology(RSM).With three major characteristic components (baicalin,praeruptorin A and solid content in extraction liquid),the effects of four factors,such as the concentration of ethanol,the dosage of ethanol,the duration of extraction and the extraction times,were investigated by the single factor experiment.Then,the range of parameters of key factors was further studied and explored by Box-Behnken RSM.The results of single factor experiment and Box-Behnken design showed that the optimum preparation conditionswere 8-fold 70% ethanol,extracted for 2 times,with 1.0 h per each time.Under these conditions,the transfer rates of baicalin and praeruptor in A were 89.57% and 87.90%,respectively.And the transfer rateof solid content was 32.35%.It was concluded that the single factor experiment combined with RSM can be used in theoptimization of extraction technology for SFDC granules in the HQ group.This technique wasstable and feasible,which provided scientific evidences for the industrial production.
6.IgM nephropathy with nephrotic syndrome in children
Zhihui LI ; Ying WANG ; Cuirong DUAN ; Tianhui WU ; Yunfeng DING
International Journal of Pediatrics 2015;42(3):334-337
Objective To investigate the clinical charactors and treatment of IgM nephropathy with nephrotic syndrome(NS) in children.Methods Thirty-six IgM nephropathy patients hospitalized in Hunan Children's Hospital as research group(group A),from June 2005 to June 2012.One hundred and six patients with minimal change disease (MCD) as control group (group B),followed up for 1 ~ 8 years.Results (1) Hematuria at presentation of the two groups respectly 3.8% vs 30.6% (x2 =20.403,P < 0.05).(2) Renal pathology revealed that there were 26 (72.2%)patients with minimal change disease,9 cases (72.2 %)with moderate membranoproliferative glomerulonephritis,1 cases with focal segmental glomerulosclerosis.(3) According to renal pathology,group A patients were divided into two sub groups:mild group and moderate group.To compared with group B,the steroid-resistant incidence of the 3 group were respectly 12.3%,19.2%,77.8% (x2 =24.369,P < 0.05).There was no significant difference between control group and mild group.(4)The remission rate of proteinuria in steroid-resistant patients who combined to use mycophenolate mofetil (MMF) with the two groups were respectively 50% and 85.7 % (x2 =3.60,P > 0.05).Conclusion Incidence of hematuria is higher in IgM nephropathy patients and patients with renal pathology for moderate lesions have a high steroid-resistant,and need use immunosuppressive early.MMF may be a good immunosuppressive for theses patients.
7.Inhibiting NF-κB activity down-regulates angiotensinogen expression level in cultured rat mesangial cells
Jin LI ; Ying GUO ; Bin HUANG ; Helin DING ; Zuzhi FU
Chinese Journal of Endocrinology and Metabolism 2010;26(5):411-412
The angiotensinogen(AGT) expression and angiotensin Ⅱ (AngⅡ ) secretion levels in cultured SD rat mesangial cells were determined. High glucose up-regulated AGT mRNA(0. 29±0.07 vs 0. 20±0. 05,P< 0.05)and protein(0.66±0.23 vs 0.37±0. 15,P<0.05) expression and Ang Ⅱ secretion [(9.85±2.08 vs 7.50± 1. 51) pg/ml,P<0. 05]levels, which were down-regulated by pyrrolidine dithiocarbamate( PDTC) treatment via inhibiting NF-κB activity.
9.Study on screening protein secretion after TGF-?1 stimulation of gastric cancer cells by SELDI-TOF-MS technique
Ying LIU ; Jifang WEN ; Shi DING ; Xuelan LI
Chinese Journal of General Surgery 2001;0(10):-
Objective SELDI-TOF-MS technology was used to contrastly analyse the changes of protein expression profiles of gastric cancer cells after TGF-?1 stimulation,and provide theoretical and experimental foundation for screening different significant proteins. Methods Serial subcultivation gastric cancer cells BGC823,MKN45,and SGC7901 cultured in vitro were grouped into test and control groups.TGF-?1 was added to the test group,but not to control group.Cell culture fluid was collected and centrifuged after cultured 24h,and crossing with WCX2 protein chip to detect protein differences. Results When the test group was compared with control group,we found:(1) thirteen different proteins in BGC823 cells after TGF-?1 stimulaton,and their M/Z were M4294,M4932,M4945,M4972,M4991,M5015,5036,M5060,M5153,M5180,M5197,M8577,and M8784,respectively;(2) eighteen different proteins in MKN45 cells after TGF-?1 stimulaton,and their M/Z were M4292,M4931,M4945,M4972,M4990,M5014,M5152,M5178,M7055,M8190,M8570,M8652,M8670,M8780,M9963,M10098,M10523,and M11653,respectively;(3) eight difference proteins in SGC7901 cells after TGF-?1 stimulation,and their M/Z were M4945,M4972,M4992,M5015,M5180,M7056,M8573,and M8604,respectively. By comparing three protein expression profiles of gastric cancer cells after TGF-?1 treatment,we found two significcant proteins with common differences,that had M/Z of M4945 and M4972,respectively. Conclusions The biological markers whose M/Z is M4945,M4972 with gastric cancer characteristic and associated with TGF-?1 have been screened,which can be as the basis for early prediction and clinical diagnosis research on metastasis and invasiveness of gastric cancer.
10.Clinical observation on effect of Lei's Danshen Tablets in treating patients with angina pectoris
Wenhuan MA ; Zhijiang DING ; Ying LI ; Ruifang WANG
Chinese Traditional Patent Medicine 1992;0(08):-
0.05). After the treatment the level of ?bl, ?bh, ?p of treated group degraded obviously (P