OBJECTIVE:To investigate the improvement effect of Eucalyptol enteric soft capsule on mice with lipopolysaccha-ride(LPS)-induced acute lung injury(ALI). METHODS:60 mice were randomly divided into blank control group,model control group,Eucalyptol enteric soft capsule low-dose,medium-dose,high-dose groups(100,300,900 mg/kg),12 in each group. Mice in administration groups were intragastrically given relevant medicines,mice in blank control group and model control group were intragastrically given equal volume of normal saline(0.1 mL/10 g). After 2 h of administration,except for the blank control group, ALI was induced in other groups by atomized LPS. After 6 h of modeling,the mice were sacrificed,alveolar lavage fluid(BALF) and lung tissue were taken. Morphological changes of lung tissue were observed under microscope;number of total cells,neutro-phils in BALF were calculated by blood cell count plate and staining by wright-giemsa respectively. Total protein concentration in BALF supernatant was detected by BCA method;TNF-α,IL-6 contents in BALF supernatant were determined by enzyme-linked immunosorbent assay. RESULTS:Compared with blank control group,lung tissue of mice in model control group showed obvious pathological damage and severe pulmonary edema;number of total cells,neutrophils in BALF,total protein concentration and TNF-α,IL-6 contents in BALF supernatant were significantly increased(P<0.01). Compared with model control group,pathologi-cal damage in lung tissue of mice was obviously improved in Eucalyptol enteric soft capsule high-dose group,number of total cells,neutrophils in BALF,total protein concentration and TNF-α,IL-6 contents in BALF supernatant were significantly decreased (P<0.05);and there were no significant differences in other groups (P>0.05). CONCLUSIONS:High-dose Eucalyptol enteric soft capsule can obviously improve LPS-induced ALI of mice.

Objective To investigate the rate of lower reproductive tract infection during pregnancy and the its impact on pregnancy outcome.Methods Five hundred and twenty pregnant women were enrolled in the study who were hospitalized for delivery from Jan.2010 to Jan.2012 at Hebei Port Group Company Limited Harbor hospital.All pregnant women were performed the bacteria detection in vagina before delivery,including candida albicans,bacterial vaginosis,trichomonas,mycoplasma,trachomatis and Neisseria gonorrhoeae,group B hemolytic streptococci GBS.The pregnant outcomes were followed.According to the results of bacteria detection,107 patients (20.58％) were with varying degrees of vaginitis and they were served as positive group.Other 403 patients were served as negative group.Results (1) Of 107 vaginitis women,48 cases (44.86％) were infected with candida albicans,and 22 cases (20.56％) were with bacterial vaginosis.The infection by mycoplasma,chlamydia,group B streptococcal infections were majority,while the trichomonas vaginalis,Neisseria gonorrhoeae infection were minority.(2) Compared with the negative group,incidence of premature rupture of membranes,preterm birth,puerperal infection and fetal distress in positive group were higher and the differences were significant(15.89％ vs.5.08％,12.15％ vs.3.15％,8.41％ vs.1.94％,5.61％ vs.1.21％ ; x2 =14.642,14.498,11.264,7.934; P ＜ 0.01).Conclusion The incidence of genital tract infection is higher during the pregnancy.Bacteria infection detection should be performed and treated as early as possible in order to reduce the occurrence of adverse pregnancy outcome.

To explore the mechanisms of scalp acupuncture in treating cerebral ischemia in rats.

Objective To investigate the influence of smoking,drinking cognition and behavior among the officers and soldiers in South China War Zone after health management,and to explore the establishrent of appropriate health management model for the army.Methods Harmfulness cognition,rate,quantity,types of drinking and smoking were investigated and analyzed before and after health management among 1 102 officers and soldiers in South China War Zone by providing a set of health education,psychological counseling service,disease and lifestyle intervention of health management as a whole.Results The harmfulness cognition rate of smoking and drinking raised from 95.6％ and 94.1％ to 98.7％ and 97.8％,the smoking and drinking rate dropped from 64.7％ and 72.6％ to 37.2％ and 61.4％ after health management.The x2 values were 18,18.9,153,20.8,and had significant difference (P＜0.001).The rate of occasional smoking,a small amount of smoking,often smoking dropped from 28.3％,25.8％,45.9％ to 18.5％,12.2％,31.5％ as well as the rate of occasional drinking,a small amount of drinking,often drinking has dropped from 56.6％,32.3％,11.1％ to 49.8％,23.4％,4.1％.The x2 values were 26.8,62.1,31,9.61,8.06,19.4,and had significant difference (all P＜0.01).Conclusion The health management improves the harmfulness cognition of smoking and drinking,and decreases the rate and quantity of smoking and driking.It has a positive effect on improving the heahh literacy and developing health way of life in officers and soldiers.

Diverticulum ; congenital ; Female ; Humans ; Tracheal Diseases ; congenital

Objective To study the changes of bone mineral density(BMD)and bone turnover in postmenopausal osteoporotic patients treated with salmon calcitonin nasal spray. Methods Sixty-seven postmenopausal osteoporotic patients were enrolled in our trial. All of them received calcium and vitamin D; 37patients were treated with salmon calcitonin nasal spray for 12 months and the other 30 patients received calcium and vitamin D only. Dual-energy X-ray absorptiometry(DEXA)and measurements of a series of bone turnover indices were performed before and after medication for 6 and 12 months. Results After treatment with salmon calcitonin nasal spray for6 months, BMD in lumbar spine 2-4 increased but no change occurred in femoral neck. However, after treatment for 12 months, BMD in both lumbar spine 2-4 and femoral neck increased. In the control group, BMD in lumbar spine 2-4 decreased after treatment for 6 and 12 months, but BMD in femoral neck decreased only after 12months. Comparing with the control group, after treatment with salmon calcitonin nasal spray, BMD in lumbar spine 2-4 and femoral neck were increased obviously. The level of TRACP-5b and NTX/Cr decreased after treatment with salmon calcitonin nasal spray for6 months and 12 months, while BALP increased only after treatment for 12 months. In the control group, BALP decreased after treatment for 12 months. The level of 25-(OH)vitamin D increased after treatment for 6 months and 12 months in both groups. Conclusions Long-term treatment with salmon calcitonin nasal spray prevents bone loss and may increase bone mass.

OBJECTIVE:To overcome the shortcoming of manual method,computer-aided manufacturing (CAM) system of prosthetic socket is applied to improve socket's quality and processing efficiency,which also reduces the demand of operator's knowledge and experience.METHODS:Prosthetic socket CAM system was discussed based on an advanced manufacture technology,and the hardware and software were designed.The advanced manufacture platform was composed of an industrial personal computer (IPC),a motion control card,four sets of Panasonic digital AC servo control system,four lead screw guides,two spindle motor of milling cutter,a transducer,two switching power supply,limit switch and proximity switch.The software of prosthetic socket CAM system mainly included three function modules:parameter setting,machine testing and beginning processing.Through adjusting command pulse's input and driver's coefficient,the motor worked at different speeds.RESULTS:The result of experiment demonstrated that maximum rotational speed restriction was applied to protect the motor,and the motor could work very smoothly without vibration in very low speed.It was suitable for manufacture prosthetic sockets,and could manufacture the high quality prosthetic socket to satisfy the requirements of amputee.CONCLUSION:Prosthetic socket CAM system based on the advanced manufacture platform can overcome the shortcoming of traditional manual method,ensure product quality,and reduce the cost.The protracted experience of certified prosthetist was incorporated into the design program to reduce the demand of manipulator's knowledge and experience,increase the one-time success rate of manufacture prosthetic sockets,and improve the quality uncertainty of sockets.It can change the backward production mode of designing,measuring,taking model,and modifying model which depends on handwork.

Bilingual teaching is one of education reform in China.The essay analyzed the necessity of bilingual teaching and clarified the reason why it can procced in microbiology.Search after the way in microbiology course according to the character of college in western China.The practice accumulated experience for bilingual teaching.

Objective To investigate the group B streptococcus( GBS)colonization rate and the relationship between vaginal colonization of GBS and the pregnancy outcome. Methods Five hundred and twenty cases pregnant women were selected as our subjects. Microbiological culture was used for culture of GBS in 1 / 3 of vagina and rectus before delivery,other samples from different sites after delivery(including neonatal throat,ear and placenta). Results (1)The GBS carrier rate in 520 pregnant women was 10. 19%(53 / 520). (2)GBS carrier rate in neonatal was 8. 85%(46 / 520). The carrier rate of neonatal whose mothers also carried GBS was 22. 64%(12 / 53),higher than that of non-carrier mothers(7. 28%(34 / 467),χ2 = 8. 192,P < 0. 05) . The rate of pneumonia and the upper respiratory tract infection of neonatal with GBS-carrier-mother were 20. 75%(11 / 53)and 18. 87%(10 / 53),higher than that of non-carrier mothers(8. 57%(40 / 467)and 4. 71%(22 / 467)). The pneumonia rate and upper respiratory tract infection of GBS positive neonatal were 21. 73%(10 / 46)and 19. 56%(9 / 46),higher than GBS negative one(8. 65%(41 / 474);4. 85%(23 / 474)). and there were significant differences(χ2 = 8. 121,15. 717;P < 0. 05).(3)The incidence of intrauterine infection and fetal distress of neonatal with GBS( + )mother were 47. 17%(25 / 53),15. 09%(8 / 53),significantly higher than that of negative(7. 07%(33 / 467),4. 71%(22 / 467)),and the differences were statistically significant( χ2= 77. 248,9. 440;P < 0. 05). But there were the similar incidence in term of premature rupture of fetal membranes,premature occurrence rate between GBS positive and negative mothers( 28. 30%( 15 / 53 ) vs. 28. 48%(133 / 467;3. 77%(2 / 53)vs. 2. 36%(11 / 467);χ2 = 0. 001,0. 393;P > 0. 05). The rate of GBS positive with mycotic vaginitis,placenta previa ratio were 39. 62%(21 / 53),7. 55%(4 / 53),higher than that of GBS negative one(20. 56%(96 / 467),1. 93%(9 / 467)),and the differences were statistically significant(χ2= 9. 922,6. 168,P < 0. 05). Conclusion Maternal GBS carrier at 35 - 37 weeks of gestation can lead to adverse pregnancy outcome by increasing intrauterine infection fetal distress and neonatal infections. Screening of GBS should be performed routinely in late gestation.

This study was aimed to establish a fast determination method of main components in honey. Honey samples from difference production bases were used as study objects. Transmission and reflection spectra of different honey samples were collected with the Fourier transform near infrared spectrometer. The main components in honey (moisture content, fructose content, glucose content and reducing sugar content) were detected by the near infrared quantitative analysis technique. The near infrared quantitative analysis models of moisture content, fructose content, glucose content and reducing sugar content in honey were established by the partial least squares (PLS). The results showed that the correlation coefficient (r) of the moisture content, fructose content, glucose content and reducing sugar content in honey were 0.997 25, 0.973 90, 0.927 94 and 0.952 68, respectively. The root mean square error of prediction (RMSEP) were 0.165 (%), 0.564 (%), 1.300 (%) and 1.270 (%), respectively. It was concluded that determination of main components in honey by the near-infrared spectroscopy technology was a fast and nondestructive determination method with high accuracy, which can be used in the quantitative detection of main components in honey.