1.The Type of Blood Vascular Supply to Pulmonary Carcinoma and Its Influences to the Intervention Methods and Curative Effect
Julang ZENG ; Yanhao LI ; Siyuan XIA
Journal of Interventional Radiology 1994;0(02):-
Purpose: To discuss the influences of blood vasculature of pulmonary carcinoma to the intervention methods and curative effect and its clinical significance. Materials and Methods.(1) The bronchical arterigrams in 60 cases of advanced stage pulmonary carcinoma were analyzed retrospectively. (2) 35 cases were treated with BAI(bronchical arterial infusion) and BAE(bronchical arrterial emboliza- tion), 25 cases with BAI alone. Treatment persisted for 4 weeks. Results: 36 cases were hypervascular 20 cases with moderate vasculature and 4 cases belonged to hypovascular. The efficiency rate of BAI and BAE 76.7% and total efficieney rate is 95%. No severe complications have taken place. Conclusion: BAI and BAE are effective for pulmonary carcinomas of hypervasculas and moderate vascular types. They are safe, effective and simple methods.
2.Early Peritoneal dialysis after repair of congenital heart disease in children
Min ZENG ; Shoujun LI ; Xu WANG ; Jun YAN ; Xia LI
Chinese Journal of Thoracic and Cardiovascular Surgery 2013;(2):73-75
Objective The mortality rate of the children after surgical repair of congenital heart disease associated with acute renal injure has been reported to be 30%-79%.Peritoneal dialysis is the common treatment method for those patients,but the optimal time to initiate peritoneal dialysis is still controversial.The aim of this study was to investigate the clinic outcome of early peritoneal dialysis to the children following cardiac surgery.Methods We performed a retrospective chart of children following cardiac surgery from January 2008 to December 2009.The total number was 4561,62 of them were performed PD treatment.Data on the PD treatment children were collected from pre-operation to hospital discharge.Early peritoneal dialysis group was defintes as PD initiated at operation room or the interval between the end of operation to starting peritoneal dialysis less than 3hrs.the others were traditional PD group.Results The whole PD treatment rate was 1.36%,15 patients died.The mortality were 10.71% (3/28) in early PD and 35.29% (12/34) in conditional PD group respectively (P =0.036).2 patients were met RIFLE(risk,injury,failure,loss,and end-stage renal disease,RIFLE)classification as failure grade in early PD group while 10 patients in traditional PD group (P =0.001).After PD treatment 24hrs,the Vasoactive-Inotrope Scores and serum creatinine values were much lower in the early PD group children than those in the traditional PD group[(19.00 ±2.39) vs(37.00±5.22),P=0.002;(50.51 ±21.84) vs(130.13±76.09),P=0.001)].Conclusion This study shows that early PD can prevent the children after congenital heart surgery to develop AKI,and reduce the severity of the clinic status.Early intervention with PD is associated with low mortality.
3.Effect of first, second, and third trimester placental factorson CD4, CCR5,and CXCR4 expression in human peripheral blood lymphocytes
Liping LI ; Jiali KANG ; Wei XIA ; Yaoying ZENG
Journal of Central South University(Medical Sciences) 2008;33(6):461-467
Objective To investigate effect of first, second, and third trimester placental factors (PF) on CD4, CCR5, and CXCR4 expression in human peripheral blood lymphocytes (PBLs), and to explore their influence on human immunodeficiency virus (HIV) vertical transmission.Methods Human peripheral blood mononuclear cells (PBMCs) were treated with first, second,and third trimester PF (concentration 25%) respectively for 24 hours. The expression of CD4, CCR5,and CXCR4 in PBLs, and the percentages of CCR5+, CXCR4+,and CCR5+CXCR4+ cells in peripheral blood CD4+ lymphocytes were determined with flow cytometry.Results All trimester PFs reduced CCR5 expression in PBLs. The efficiency of the first trimester PF was higher than that of the second and third trimester PF. The percentage of CCR5+ cells in peripheral blood CD4+ lymphocytes of PF groups was significantly lower than that of the control group, and the percentage of CCR5+ cells in peripheral blood CD4+ lymphocytes of the first trimester PF group was significantly lower than that of the second and third trimester group. The percentages of CCR5+CXCR4+ cells in peripheral blood CD4+ lymphocytes of PF groups were significantly decreased as compared with the control group, and the percentage of CCR5+CXCR4+ cells in peripheral blood CD4+ lymphocytes of the first trimester PF group was significantly lower than that of the third trimester PF group.Conclusion PF can reduce the expression of CCR5 in human PBLs and peripheral blood CD4+ lymphocytes, indicating that PF might reduce R5 virus infection via preventing HIV entry, and might play an important role in reducing R5 virus intrauterine infection.
4.Effects of isoflurane and sevoflurane on neuronal proliferation and expression of ERK1/2 protein in the hippocampi of neonatal rats
Shuxuan XIA ; Yujuan LI ; Jing ZHANG ; Minting ZENG ; Chuiliang LIU
Chinese Journal of Behavioral Medicine and Brain Science 2013;(4):299-302
Objective To investigate the effects of isoflurane and sevoflurane at the equivalent depth of subanesthesia on neuronal proliferation and phosphorylation of extraceullar signal-regulated kinase 1/2 (ERK1/2)protein in the hippocampi of neonatal rats.Methods Seventy-two neonatal rats at postnatal day 7 were involved in this study and they were assigned randomly into isoflurane group (Iso group),sevoflurane group (Sev group) and control group (Con group).The rats in I group,S group or C group were separately exposed to 0.75% isoflurane or 1.2% sevoflurane (equivalent to 0.3 MAC for neonatal rats) or air for 6 h.Some rats in each group were injected intraperitoneally BrdU 100 mg/kg immediately (D0) (n =6) or 3 days after exposure (D3) (n =6),and their brains were perfusion and embedded by paraffin 24 h after BrdU injection.BrdU positive expressions in the in dentate gyrus (DG) area of hippocampus were detected by IHC staining.Besides,the fresh hippocampi of some rats each group were dissected at the end of anesthesia,caspase-3 and phospho-ERK1/2,ERK1/2 proteins expression were detected by Western blot (n =6).The other rats in each group were used to measure changes of pH and blood glucose (n =6).One way ANOVA test was used for data analysis among groups.Results BrdU-positive cells had no significant difference among group IsoD0 ((1332.43 ± 192.70)/mm2),group SevD0 ((1207.33 ±139.50)/mm2),and group ConDO ((1362.40 ± 227.90)/mm2) at D0,while which had significantly decreased by 32.6% (P< 0.05) in group IsoD3 ((604.56 ± 65.77)/mm2) when compared with those in group ConD3 ((896.90 ± 78.77)/mm2) at D3.There was no significant difference between groups of SevD3 ((808.73 ± 41.27)/mm2) and ConD3.The expression of caspase-3 protein was increased by 195% (P< 0.01) in Iso group while which only increased by 74% (P < 0.05) in Sev group when compared with Con group.The expression of P44 and P42 of phospho-ERK1/2 protein in the hippocami decreased by 53% (P < 0.01) and 47% (P < 0.01))seperately in Iso group when compared with Con group,while there were no significant differences between Sev group and Con group.Conclusion 0.3 MAC isoflurane,not sevoflurane inhibits neuronal proliferation in DG of hippocampi in the neonatal rats.Inhibiting ERK1/2 phosphorylation may involve in the mechanisms of that isoflurane inhibits neuronal proliferation.
5.Relation between enlarged volume of medial wall and degree of enophthalmos after orbital fracture
Ruohui YU ; Xia WANG ; Jianning LI ; Xin YANG ; Xiangzhu ZENG
Chinese Journal of Medical Aesthetics and Cosmetology 2010;16(6):376-379
Objective To explore the relation between the enlargement of orbital volume and the degree of enophthalmos, and that between the enlarged volume of floor together with that of medial wall and the degree of enophthalmos. Methods A total of 17 patients of unilarteral orbital fracture were scanned by MSCT (slice width 0.625mm), who suffered late enophthalmos as a results of combination fracture of the medial wall and floor. The clinical data were collected, and input into a software named MIMICS in order to measure orbital volume, the degree of enophthalmos, the enlarged volume of medial wall, and that of orbital floor. Simple linear correlation and regression were carried out between the enlargement of orbital volume and the degree of enophthalmos. Mutiple linear correlation and regression were carried out between the enlarging volume of floor together with that of medial wall and the degree of enophthalmos. Results The equation of the enlargement of orbital volume (V) and the degree of enophthalmos (E) was E= 0.851 V-0.197 (Pearson r=0.969, P<0.01, the 95% confidence intervals of 0.732-0.970). The standardized equation between the enlarged volume of floor together with that of medial wall and the degree of enophthalmos was E= 0.690 VF+0.413 VM-0. 086 (setpwise, entry =0.5, removal= 0. 11,P<0.01 ); Comparing the standardized coefficients of independent variables, the outcome was bF (0.690) > bM(0.413). Conclusion Significant linear correlation between the increment of the orbital volume and the degree of enophthalmos is found that 1.0 ml enlargeement in bony volume causes approximately 0.9 mm of enophthalmos; enlarged volume of floor has more powerful influence on the degree of enophthalmos than enlarged volume of medial wall, the former is 1.56 times of the latter.
6.Follow-up survey on psychological health status in persons bit by dogs
Baolong ZHAO ; Xiaobing ZENG ; Xia WANG ; Chunbo LI
Chinese Journal of General Practitioners 2010;9(4):252-254
Objective To investigate psychological health status and its change in short term among persons bit by dogs.Methods Psychological health status was evaluated with patient health questionnaire (PHQ-15) Chinese version for the 613 wounded persons bit by dogs,including 368 males and 245 females with average age of 36 years plus or minus 14 years (standard deviation),meanwhile their wounds were handled routinely at clinics,as well as health education and cognitive psychological intervention were provided for them.Results All of the 613 persons with dog bites had mild or moderate somatic syndrome in their initial visits and 478 of them (78.0%) still presented mild somatic syndrome and only 23 (3.7%)with moderate symptoms four week after dog bites by PHQ-15 scores.One hundred and fifty-two of 613 (24.8%) followed-up at their initial visits had depressive symptoms,which could remain in 61 of them (10.0%) four weeks after bites.Two hundred and eighty-four of them (46.3%) had anxiety symptoms at initial visits,and 258 (42.1%) still had mild and nine (1.5%) had moderate symptoms four weeks after bites.Conclusions Psychological symptoms were popular in wounded persons by dog bites,which can persist for a certain time.PHQ-15 can be used for evaluating their psychological status.
7.Application of fresh whole blood in comparison and bias estimation between different hematocyte analyzers
Xia HOU ; Deyao DENG ; Zeng′an LI ; Weijuan TIAN ; Lihong ZHU ;
International Journal of Laboratory Medicine 2014;(22):3099-3101
Objective To compare the detection results and estimate the bias of two hematocyte analyzers of different brands . Methods Sysmex XE‐2100 hematocyte analyzer and Abbott CD‐1700 hematocyte analyzer were chosen to be the reference instru‐ment and comparison instrument ,respectively .40 cases of fresh whole blood samples were collected for the detection of WBC ,RBC , HGB ,HCT ,MCV ,MCH ,MCHC ,and PLT respectively by the two instruments .The correlation coefficient (r) ,regression equa‐tions and bias were calculated and compared to determine the comparability of the two instruments .Results The precisions of two hematocyte analyzers were satisfactory .When fresh whole blood was used as calibrators ,the results of all eight items of the two in‐struments had good correlations (r>0 .975) ,and the relative bias was acceptable .Conclusion The results of two hematocyte ana‐lyzers are comparable .With fresh whole blood using in the comparison test between different hematocyte analyzers ,systematic er‐rors can be discovered in time .
8.Nursing care of one patient with hepatic ectopic pregnancy treated by laparoscopy with preservation of liver
Gaoli SU ; Jinghua ZENG ; Xiufang XIA ; Yan LI
Chinese Journal of Nursing 2017;52(4):446-448
This paper summarized nursing care of a case with hepatic ectopic pregnancy treated by laparoscopy with preservation of liver.Nursing key points included:psychological nursing,medication guidance before surgery,prevention of hepatorrhexis,close observation and monitoring of changes in condition,pipeline nursing,monitoring of liver function and blood HCG after surgery.The operation was successful and the patient had good compliance with all treatment.The patient recovered from the surgery and was discharged nine days after operation.
9.Researching development about exercise rehabilitation of postoperative patients with coronary artery bypass graft
Yebin NI ; Xia DUAN ; Jinxia JIANG ; Li ZENG
Chinese Journal of Practical Nursing 2017;33(17):1348-1351
This paper summarizes the development of exercise rehabilitation, the development patterns, sports teams, intervention methods and effects after coronary artery bypass surgery. Advisers of exercise rehabilitation have different jagged currently. Recovery patterns and forms, movement of the time exist similarities and differences. We also need to further explore the objective and scientific exercise rehabilitation modes after coronary artery bypass surgery to solve these problems.
10.Finite element analysis of femoral neck fracture with different fixation ways
Zhifeng XIA ; Ming LIANG ; Yafeng LI ; Guannan ZENG
Chinese Journal of Tissue Engineering Research 2016;20(31):4630-4636
BACKGROUND:Finite element method is widely used in the femoral neck fracture, but the study concerning different fixation methods of femoral neck fracture is not much. OBJECTIVE:To analyze biomechanical properties of different fixation methods for femoral neck fracture using finite element analysis. METHODS:The femur of voluntters was scanned with CT, at thickness 0.6 mm, from the site above the greater trochanter of the femur. Scanning data were saved in .DICOM format. Data of right proximal femur were imported into Mimics software. Osteotomy was performed according to Pauwels I type fracture. Models of two tensile force screws, ful y threaded hol ow screw and proximal femoral locking plate were established. Three-dimensional finite element method was used to analyze stress distribution, stress concentration position, displacement distribution and maximum displacement in different models of femoral neck fracture with different internal fixation methods. RESULTS AND CONCLUSION:(1) The maximum stress value of two lag screws model was biggest. The maximum stress value of ful y threaded hol ow screw model was minimized. The maximum stresses of two lag screws model, ful y threaded hol ow screw model and proximal femoral locking plate model al were concentrated in the fixed end of fractures. (2) The femoral maximum stress of two lag screws model was biggest. The femoral maximum stress value of proximal femoral locking plate model was minimized. The femoral maximum stresses of two lag screws model, ful y threaded hol ow screw model and proximal femoral locking plate model al were concentrated in the medial femoral smal rotor near and medial femoral and fixation contact points. (3) The maximum displacement of two lag screws model was biggest. The maximum displacement of ful y threaded hol ow screw model was minimized. The maximum displacement of two lag screws model, ful y threaded hol ow screw model and proximal femoral locking plate model al was in the femoral head. (4) The maximum displacement value of two lag screws model fixed place was biggest. The maximum displacement value of ful y threaded hol ow screw model fixed place was minimized. The maximum displacement value of two lag screws model was biggest at femoral head. The maximum displacement value of ful y threaded hol ow screw model was minimized at femoral head. (5) Results showed that the treatment effect of ful y threaded hol ow screw on Pauwels I fractures was better than other two fixation methods.