BACKGROUND:Critical limb ischemia is difficult to be treated among the peripheral arterial occlusive diseases, and the application of transplanting autologous stem cells can bring a hope for the treatment of this disease.
OBJECTIVE: To review the autologous stem cells transplantation in the treatment of critical limb ischemia at present, and to study the mechanism and the existing problems.
METHODS:A computer retrieval of PubMed database, Wanfang database, and CNKI database was conducted to search the related articles with the keywords of“stem cell, transplant, critical limb ischemia”in English and Chinese. Final y, 47 articles were included in final analysis according to the inclusion criteria.
RESULTS AND CONCLUSION:Autologous stem cells transplantation for treatment of lower extremity ischemic disease is a latest and significantly effective treatment, but the mechanism is unclear and stil needs further study.

Objective To investigate the role of sitting-up-straight position in correction of peripherally inserted central catheter(PICC)heterotopia.Method Eighteen cases with PICC heterotopia were instructed to take the position of sitting up straight. Result All of the patients had the PICC heterotopia corrected.Conclusions The sitting-up-straight position can effectively correct the PICC catheter heterotopia.This method is simple and feasible and thus worthy of clinical application.

Objective To observe the clinical effect of nasal douche washing and nasal cleaning under the endoscope treatment for sinusitis after nasopharyngeal carcinoma radiotherapy.Methods Thirtyeighty cases of sinusitis after nasopharyngeal carcinoma radiotherapy was treated by nasal douche washing and nasal cleaning under the endoscope.The course of treatment were for 6 months.The clinical effect were evaluated with the chronic sinusitis visual analogue scale(VAS)and Lund-Mackey nasal sinuses CT image mark system before and after treatment.Results After treatment for 6 months,the VAS scores and LundMackey nasal sinuses CT image mark system scores significantly decreased compared with before treatment [(8.21 ± 1.57)scores vs.(3.01 ± 1.16)scores,(7.37 ± 1.44)scores vs.(3.23 ± 1.07)scores](P ＜ 0.05).Conclusions The nasal douche washing and nasal cleaning under the endoscope treatment for sinusitis after nasopharyngeal carcinoma radiotherapy has positive clinical effect,which is a better treatment method.

Animals ; Hypothyroidism ; physiopathology ; Learning ; Memory ; Mice ; Motor Activity

Objective : To analyze the trend of lung cancer incidence in Shaoxing, Zhejiang Province from 2014 to 2019, so as to provide the basis for lung cancer prevention and control. Methods : The data of lung cancer were collected through the information management system of chronic disease surveillance in Zhejiang Province.The crude incidence rate, age-standardized incidence rates by Chinese standard population ( ASIRC ) and by world standard population ( ASIRW ), truncated rate ( 35-64 ) years old ), and cumulative rate (0-74 years old) were calculated. The annual percentage change ( APC ) was used to analyze the trend of lung cancer. The annual contribution rate was used to analyze the contribution of the incidence trend with age to the total trend. Results : Totally 22 261 cases of lung cancer were reported in Shaoxing from 2014 to 2019. The crude incidence rate, ASIRC, ASIRW, truncated rate ( 35-64 years old ), and cumulative rate ( 0-74 years old ) were 83.51/100 000, 41.28/100 000, 41.01/100 000, 57.00/100 000 and 5.11%, respectively. The crude incidence rate, ASIRC and ASIRW increased significantly from 2014 to 2019, with the APC values of 8.56%, 6.42% and 6.05%, respectively ( P<0.05 ). The crude incidence rate, ASIRC, ASIRW, truncated rate ( 35-64 years old ), and cumulative rate ( 0-74 years old ) of man were 105.25/100 000, 48.09/100 000, 50.69/100 000, 62.03/100 000 and 6.42%, respectively, which were higher than those of women ( 61.84/100 000, 33.05/100 000, 31.35/100 000, 51.71/100 000 and 3.76% ).The crude incidence rate increased with age. The annual contribution rates of lung cancer incidence in people aged 15-<45 years, 45-<55 years, 55-<65 years and ≥65 years were 51.20%, 30.86%, 15.79% and 2.15%, respectively. The crude incidence rate in people aged 15-<45 years, 45-<55 years and 55-<65 years increased significantly from 2014 to 2019, with the APC values of 23.84%, 13.79% and 6.78%, respectively ( P<0.05 ). Conclusion From 2014 to 2019, the incidence of lung cancer in Shaoxing shows an increasing trend, and the age of onset is getting younger.

Objective To explore the accuracy of hysteroscopy as a diagnosis for endometrial carcinoma and to determine if the procedure increase the rate of positive peritoneal cytology in the patients. Methods The peritoneal cytology of 36 patients with endometrial carcinoma diagnosed by D&C or hysteroscopy was retrospectively analyzed. Results The peritoneal cytology was positive in 1 (5.9%) of the 17 cases diagnosed by D&C and 2 (10.5%) of the 19 cases diagnosed by hysteroscopy (P=1.000). Based on the pathological examination,the accuracy of D&C was 52.9% (9/17),which was significantly lower than that of hysteroscopy [89.5% (17/19),P=0.025]. In the cases with stage Ⅰ endometrial carcinoma,the diagnostic accordance rate of hysteroscopy was 85.7% (12/14),while that of the D&C was 42.9% (6/14,P=0.040). The 36 patients were followed up for 2 months to 4 and a half year (over 1 year in 28 cases). One patient with Ⅲc stage carcinoma died of recurrent tumor in 2 years after the treatment. Conclusion Hysteroscopy shows higher diagnosis accuracy with no evidence indicating an increased rate of positive peritoneal cytology compared to D&C.

Objective To investigate the effect of mental diathesis training on recruits' psychological health.Methods A total of 200 recruits were divided into intervention group and control group with 100 recruits in each group.Those in intervention group were trained by Mental Diathesis Training for 6 weeks,and the recruits in control group were not.SCL-90 and Coping styles scale were employed to evaluate the mental health before and after training.Results Except phobia and psychoticism,other factor-scores of SCL-90 of the recruits in intervention gsoup were decreased significantly after the training.Except somatization,no significant difference was found in other factor-scores of SCL-90 of the recruits in control group after the training.Except somatization,phobia and psychoticism,other factor-scores of SCL-90 of recruits in intervention group were significantly higher than that of the recruits in control group(P

Objective To investigate the influences of large-scale military exercise on immune and endocrine secretory function of soldiers.Methods The psychological stress self-evaluation test(PSET)was applied on 126 officers and soldiers before and after the military exercise.Radioimmunoassay(RIA)technique was employed to determine the contents of serum interlukine-2(IL-2),interlukine-6(IL-6),interlukine-8(IL-8),tumor necrosis factor(TNF),cortisol(Cor)and aldosterone(Ald)in 126 subjects.All data were processed by correlation analysis.Results Compared with that of before exercise,the contents of serum IL-2 declined significantly(P

Objective To investigate the correlation between the soldier' mental status and their coping style and the social supports in a jointed military exercise.Methods 538 servicemen who took part in a jointed military exercise were selected as study objects.All the objects were interviewed with the aid of Symptom Check List-90(SCL-90),Eysenck Personality Questionnaire(EPQ),Simple Coping Style Questionnaire(SCSQ)and the Social Support Rating Scale(SSRS).Collected data were analyzed by statistical methods including t-test,chi-square test and Pearson product correlation analysis.Results The SCL-90 factor scores of the study objects were significantly higher than that of Chinese military personnel norms(P

Objective To investigate the correlation between psychological stress status and the personality of the soldiers who took part in a large-scale military exercise. Methods The psychological stress self-evaluation test (PSET), SCL-90 game and Eysenck personality questionnaire (EPQ) were conducted in 126 servicemen before and after a field military exercise. Correlation between psychological stress status and their personality profile was studied versus the SCL-90 after military exercise. Results 126 servicemen who had taken part in the military exercise were tested with PSET. The number of persons whose PSET data T≥70 increased from 9 before the exercise to 35 after the exercise (P