2.Ethical thought on patients of head injury
Dongfeng WANG ; Shiwen GUO ; Tao LI
Chinese Medical Ethics 1996;0(01):-
The head injury patients is very common in clinic and it is complicated to cure them.Furthermore,many ethical questions are involved during the treatment,which are discussed in the article.The aim is to be helpful to protect both patients'and medical staff's right,reduce medical disputes and form a good relationship between doctors and patients from the view of ethics.Accordingly,the patients of head injury will acquire better treatment.
3.A Study of Right Hemisphere Function of the Nonverbal Learning Disabled Children
Jing GUO ; Longhui LI ; Deqing TAO
Chinese Journal of Clinical Psychology 2001;9(2):87-89
Objective: To study the right hemisphere function state of NLD children. Methods: Adapting tachistoscopic vision and Benton Revised Visual Retention Test (VRT), three groups involving 20 children each were studied. Results: Under the tachistoscopic vision, NLD children achived poorly in recognition of nonverbal stimulus; and they do worse also in VRT test, with more errors of omission and distortion. Conclusion: Compared with normal children, the function of NLD children's right hemisphere is relatively weaker.
4.A Study of the Schizotypal Personality Traits in the People at High Risk for Schizophrenia
Jing YAO ; Lanting GUO ; Tao LI
Chinese Journal of Clinical Psychology 2006;0(06):-
Objective: To explore the personality traits in the people at high risk for schizophrenia.Methods: 188 individuals at high risk for schizophrenia,and 321 normal controls were assessed by Schizotypal Personality Questionnaire(SPQ).Results: The score of negative schizotypal dimension in SPQ in the individuals at high risk was higher than in the normal controls.Conclusion: The people at high risk for schizophrenia have negative schizotypal personality traits which may represent a genetic endophenotype for schizophrnia.
5.Efficacy of Rehabilitation on 216 Patients with Nonspecific Low Back Pain
Xianfeng GUO ; Dacheng ZHANG ; Li TAO
Chinese Journal of Rehabilitation Theory and Practice 2010;16(6):556-559
ObjectiveTo assess different treatments on nonspecific low back pain.Methods246 subjects were assigned to 3 groups, a control group(n=82), a home exercise group(n=82) or a strengthening exercise group(n=82). Follow-up data were obtained at 1 months, 3 months and 6 months after the treatment. Primary outcome measures were modified Oswestry Low Back Pain Disability Questionnaire for disability and Numeric Pain Rating Scale for pain.ResultsThe home exercise and strengthening exercise groups experienced greater improvements in disability than the control group 6 months after the treatment. The strengthening exercise group demonstrated greater change than home exercise group.ConclusionActive rehabilitation therapy may benefit nonspecific low back pain patients.
6.Progress in Mucosal Adjuvants
Hong-Li ZHOU ; Li GUO ; Jian-Wei WANG ; Tao HONG ;
China Biotechnology 2006;0(03):-
Mucosal adjuvants play important roles in vaccine development. By now, the common used mucosal adjuvants can be divided into three categories: the bacterial derivatives, cytokines and chemokines, and antigen delivery systems. Progresses of the three kinds of adjuvants were reviewed to give a reference to novel vaccine research.
7.Investigation of Organophosphorus Pesticides Residues in Vegetables
Shuai GUO ; Li-Hua SHAO ; Jing-Tao LI ; Al ET ;
Journal of Environment and Health 2007;0(09):-
Objective To investigate the organophosphorus pesticides residues in vegetables in Ji'nan,China.Methods From 2005 to 2007,the residues of ten kinds of organaphosphorous pesticides,including methamidophos,parathion-ethyl, parathionm-ethyl,dichlorvos,phorate,monocrotophos,omethoate,dimethoate,chlorpyrifos,malathion were determined in 8 kinds of vegetables by capillary gas chromatography.Results In the 597 vegetables samples,the total detection rate of organaphosphorous pesticides was 32.66%,in 25.63% of the samples,the contents of organaphosphorous pesticides residues exceeded the national standard limits.In leek,the detection rate was 65.56% and the exceeded limit rate was 52.22%.In addition, more than one kind of pesticide could be detected in one kind of vegetable.The concentration of methamidophos,the most serious pollutant,could reach 114.013 mg/kg.Omethoate could also be detected at 11.807 mg/kg.In this investigation,a downtrend was seen in the rate of exceeding standard limits and the difference in seasons in the detection rate of pesticides residues was also seen. Conclusion The detection rate of high toxic organaphosphorous pesticides in vegetables sampled in this study is higher,it indicates that the situation of pesticides abuse is serious in this area.
8.Sedation with propofol plus fentanyl for cirrhotic patients during upper gastrointestinal endoscopy
Fengping ZHENG ; Jiayan LI ; Yunwei GUO ; Li TAO
Chinese Journal of Digestive Endoscopy 2012;29(6):311-315
ObjectiveTo prospectively study the safety and feasibility of sedation with propofol plus fentanyl for cirrhotic patients undergoing upper gastrointestinal endoscopy (UGIE).MethodsA total of 50cirrhotic patients and 50 control subjects without liver diseases referred to UGIE were assigned to the cirrhotic sedation group and the non-cirrhotic sedation group,respectively.Patients of both groups received sedation with propofol plus fentanyl.Meanwhile,30 cirrhotic patients underwent conventional UGIE.Vital signs of all subjects were recorded before sedation and procedure,five minutes,ten minutes and one hour after the procedure.Number connection test A (NCT-A) and line tracing test (LTT) were completed for all patients before sedation or procedures and 4 hours after endoscopy procedures.Occurrence of sedation-related complications was measured.ResultsIn the cirrhotic sedation group and the non-cirrhotic sedation group,blood pressure,heart rate,respiratory rate and saturation of pulse oximetry decreased of different degrees after secation (P > 0.05 or P< 0.05),but returned to normal one hour after endoscopy procedures ( P > 0.05).The total complication rates differed significantly between the cirrhotic sedation group and the non-cirrhotic sedation group [ 36% (18/50) v.s.14% (7/50),P <0.05 ].However,the rate of such complications as hypotension,bradycardia and hypoxemia in both groups was of no statistical difference (P >0.05 ).No cirrhotic patient developed overt hepatic encephalopathy after procedures.In addition,the NCT-A and LTT times before and after sedation in the cirrhotic sedation group and the cirrhotic non-sedation group were longer than those before and after procedure in the non-cirrhotic sedation group ( before sedation or procedure:(55.1 ±22.1)s,(58.6±23.1)s v.s.(36.9±7.0)s,(98.6±33.1)s,(89.5±15.6)s v.s.(81.4±13.6)s,P<0.05; four hours after procedure:(54.4 ±21.6)s,(58.3 ±22.4)s v.s.(36.3 ±6.3)s,(88.4 ±30.6)s,(80.2 ±15.9)s v.s.(71.8 ± 12.0)s,P<0.05,while there was no difference between cirrhotic sedation group and cirrhotic non-sedation group ( P > 0.05 ).Within-group comparison showed NCT-A did not change ( P > 0.05 ),whereas,LTT was obviously shorter than pre-sedation or pre-procedure ( P < 0.05) due to learning effect.The differences in the NCT-A and LTT times before and after sedation or procedure were not significant among the three groups (P > 0.05 ).ConclusionSedation with propofol plus fentanyl is relatively safe in cirrhotic patients during UGIE,which will not precipitate hepatic encephalopathy or cause irreversible complications.
9.THE BIOLOGICAL EFFECTS AND STABILITIES OF THE STABILIZED VITAMIN A, B_(2) AND C DERIVATIVES IN PRESSED BISCUITS
Ziucheng GUO ; Guiquaa TAO ; Xinru LI ; Fengzhen LI ; Deqin ZHOU
Acta Nutrimenta Sinica 1956;0(04):-
Pressed biscuits were fortified with gelatin encapsulated VA powder, VC phosphate Mg and VB2 tetrabutyrate. The biological effects of these vita-rains were examined by human experiments. In 7 days of the experimental period, the subjects of the 1st group (10 male adults) took the fortified biscuit freely which contained 7500 IU VA powder, 5.16 mg B2 tetrabutyrate ( = 3mg VB2) and 308mg VC phosphate ( = 140 mgVC) in 750 g. The 2nd group took 250 g biscuit freely containing the same amount of vitamin and unfortified pressed biscuit. The 3rd group took only the unfortified ones freely. 5 days before or after fhe experimental period the subjects ate vitamin restricted diets. The nutritional status of VB2 was estimated by 24 hrs. urinary VB2 values, that of VC by urinary and fasting plasma VC levels, and that of VA by fasting plasma VA values.The urinary levels of VB2, VC and plasma values of VC of group 1 and 2 at the end of the experimental period were significantly higher than those of the pre-experimental period. They were also higher than those of group 3. On the 5th day of the post-experimental period, the status of VB2 and VC of group 1 and 2 was still better than that of group 3. Because the subjects were not in VA deficiency, the plasma levels of VA were kept steady.The stabilities of these vitamins in the fortified pressed biscuit were compared with those of ordinary vitamins. Stored in 85% RH 32℃ for 20 months, encapsulated VA powder retained 76%, VC phosphate 84%, but the ordinary VA only 14%, VC 29%. Stored in room temp. 75% RH for 2 years, the VA encapsulated powder retained 73%, VC phosphate 96%, but ordinary VA only 8%, VC 22.3%. In room temp. for 2 years, encapsulated VA powder retained 87%, VC phosphate almost did not lost, but ordinary VA retained 8%, VC retained 25% only. The stability of the VB2 tetrabutyrate was almost the same as that of VB2. It was shown by the guinea pig growth experiment that VC phosphate in pressed biscuit stored 20 months possessed the same biological effect as VC crystal.
10.Study on adsorption specificity of HB-H-6 resin
Shuaishuai TIAN ; Yichen LI ; Di WU ; Hongxing GUO ; Tao LI
International Journal of Biomedical Engineering 2013;36(6):332-335,347
Objective The aim of this article was to deeply study the effects of different molecular weight of proteins and different structures of chemical substances on the adsorption specificity of HB-H-6 resin.Methods HB-H-6 resin was adopted to adsorb 5 different molecular weight proteins and different structural chemical substances including proteins,saccharides,human serum albumin (HAS),dextran and lipid,and then underwent static adsorption experiments in vitro.The adsorption rates of different structural chemical substances were analyzed from two experiments and the results were compared.Results The experiment results of HB-H-6 resin adsorption showed that the average adsorption rates of 5 different molecular weight proteins,myoglobin (Myo,16 700),ovalbumin (OVA,44 000),HAS (66 200),β-gal (130 000) and IgG (150 000),were significantly different:(0.00±0.33)%,(8.02± 1.23)%,(43.19±2.31)%,(34.25±1.07)% and (0.00±0.69)%.In the studies on adsorption of different structural chemical substances,the average adsorption rates of different structural chemical substances proteins,saccharides,lipid were significantly different:the absorption rates of plasma total protein,albumin,globulin,glucose,triglyceride and cholesterol groups were:(11.18±0.72)%,(10.74±0.66)%,(11.74± 1.22)%,(7.17±0.12)%,(1.06± 1.04)%,(3.05± 0.65)%.The absorption rates of HAS and dextran groups were:(43.19±2.31)% and (5.44±1.46)%.Conclusion In conclusion,the proteins' molecular weight of best adsorption condition is from 66 Ku to 130 Ku.The average adsorption rates of different structural chemical substances proteins,saccharides,lipid are significantly different.The average adsorption rates of proteins are higher than that of saccharides and lipid.It shows that HB-H-6 resin has adsorption specificity on different molecular weight proteins and different structural chemical substances.