A major task in clinical trials and researches is subject recruitment, however there probably exist ethical issues in the process of recruitment, such as the selection of subjects, recruitment methods, document de-scription,reward and compensation. This paper is to discuss the relevant ethical elements through cases analysis. It put forward that only obeying ethical codes, implementing informed consent, and playing the function of ethics com-mittee, the rights and interests of subjects can be protected.

The administration status of enteric coated aspirin in 348 diabetic patients aged over 40 from Xujiahui Subdistrict of Shanghai was surveyed. One hundred and two out 348 patients ( 29. 3% ) used aspirin regularly, among them only 36 cases used the correct dosage (75 - 162 mg/d), accounting for 10. 3% (36/348) of all patients surveyed. The results indicate that aspirin was not used properly in diabetic patients to prevent the heart and cerebrovascular diseases,and it is necessary for medical providers to promote health education for diabetic patients.

Based on the analysis of current status of medical service process including the service in out-patient, hospitalization, test, examination, nursing, and so on, the paper describes the bottlenecks and major existing problems of current medical service process. And it further discusses how to make full use of the advanced health information technology, make scientific and reasonable arrangements for all links of medical service, reconstruct medical service process facing the patients, and optimize and reengineer the medical service process.

Bibliometrics ; China ; Humans ; Journal Impact Factor ; Publications ; statistics & numerical data

Electrical stimulation is a common technology to treat neurogenic bladder dysfunction secondary to supersacral spinal cord injury. This paper reviews the historical development of this treatment and current status.

lntraocular lens ( lOL) often has different degrees of tilt, decentration and rotation in the eye. The deflection of lOL is an important factor to impact on the visual quality of the patients with cataract surgeries. Vision was commonly used to evaluate visual quality before. ln recent years, some new methods are also introduced to evaluate visual quality, such as optical aberration, modulation transfer function ( MTF ) and subjective visual perception. They show that the lOL deflection will cause decreases in eyesight and MTF, cause increase in aberration, lead to ametropia and so on. Therefore, a better evaluation of the effects of lOL deflection on visual quality, has significance for lOL selection, positioning and cataract individualized treatment.

Objective To explore the clinical effects of ropivacaine in combined spinal-epidural anesthesia (CSEA) in the aged patients undergoing lower limb surgery. Methods Sixty patients, aged 65 and over, in American Society of Anesthesiologists (ASA) physical status Ⅱ-Ⅲ, and undergoing internal fixation surgery for lower limb bone fracture, were randomly assigned to three groups in equal number: group R1 (hypobaric ropivacaine for lumbar anesthesia), group R2 (hyperbaric ropivacaine for lumbar anesthesia) and group B (bupivacaine for lumbar anesthesia). The observed variables included the changes in blood pressure and heart rate, sensory block level and motor block status. The drug consumption in epidural anesthesia and the peri-operative side effects were noted. Results The anesthetic efficacy was satisfactory in all patients. The onset time of anesthesia in group B (54.05?3.80 s) was obviously shorter than that in group R1 and group R2 (61.10?4.96 and 60.95?3.94 s, respectively, P

A combination vaccine which consists of ≥2 immunogens is intended to provide protection against two or more diseases or against multiple serotypes of a single disease. The use of combination vaccines decrease the number of vaccine injections in the regular immunization schedules. However,the development of combination vaccines is more complicated than monovalent vaccines,preservatives and adjuvants used with one component may alter the potency of other components. Physical,chemical,and biological interactions between the components of combination vaccines must be considered to avoid detrimental effects on safety or efficacy. Therefore combination vaccines present unique challenges for product evaluation. This paper presents a review of research application status,the evaluation of effectiveness and safety,as well as development prospects on combination vaccines.

Polypoidal choroidal vasculopathy(PCV) is a common disease of the retina,the disease is more found in colored race.In China,the mainly nosogenic population is the female about 60 years old.The pathogenesis of PCV is unknown and there is no specific medicine at present.The funduscopic present is orangered lesions,bleed and exudation.Indocyanine green angiography(ICGA) could make a definite diagnosis of PCV.In recent,the main treatment of PCV includes photodynamic therapy,intravitreal anti-VEGF therapy,surgery for treatment of complications and combined therapy.We review the treatment and diagnosis of PCV,and propose the further research direction.

0.05).After 3 months therapy:The TEF25%,VPEF/VE and TPEF/TE of control group were different from those of normal group statistically.4.After 1 year,the incidence of asthma of observe group was significantly lower than that of control group(P