Objective To study the effect of treating fatty liever with Tiaozhisugan decoction combined with simvastatin. Methods A total of 60 cases with fatty liver were randomly recruited into a control group and a treatment group.The control group was treated with simvastatin, vitamin E, and pioglitazone, while the treatment group was additionally treated with Tiaozhisugan decoction on that basis. Results The total effective rate was 93.9% and 79.6% in the treatment group and the control group respectively, the difference showing statistical difference (χ2=2.586, P＜0.01 ) .Conclusion It was effective to treat fatty liver with Tiaozhisugan decoction combined with simvastatin.

Acupuncture Points ; Acupuncture Therapy ; instrumentation ; methods ; Child ; Child, Preschool ; Enuresis ; physiopathology ; therapy ; Female ; Humans ; Male ; Treatment Outcome

BACKGROUND:Studies have shown that emodin protects against intestinal ischemia-reperfusion injury by inhibiting the release of inflammatory factors. OBJECTIVE:To investigate the effect of emodin on renal ischemia/reperfusion injury after bone marrow mesenchymal stem cel transplantation. METHODS:Forty Sprague-Dawley rats were randomized into five groups (n=8 per group):sham group, model group (renal ischemia/reperfusion injury group), bone marrow mesenchymal stem cel group (cel transplantation group), low-dose emodin group, high-dose emodin group. Rats in the latter four groups were pretreated with or without different concentrations (30 and 60 mg/kg) of emodin for 7 days, and then were subjected to clamping bilateral renal pedicles for 45 minutes, fol owed by injection of 1 mL bone marrow mesenchymal stem cel suspension. Six hours after reperfusion, the pathological changes of renal tissues were examined by hematoxylin-eosin staining;the mRNA levels of tumor necrosis factorα, interleukin-6, interleukin-18, TLR2 and TLR4 detected by real-time fluorescence quantitative PCR;and the protein expression of COX-2, ICAM-1 and iNOS determined by western blot. RESULTS AND CONCLUSION:Compared with the sham group, rats in the model group showed obvious features of severe acute tubular damage and inflammatory cel infiltration. In the cel transplantation group, tubular epitheliael cel s were partial y lost with some inflammatory cel s infiltrated in the renal interstitium. In the emodin groups, the tubular lumen was practical y intact with little renal interstitial inflammatory cel s. Compared with the sham group, a significant increase in the mRNA levels of tumor necrosis factorα, interleukin-6, interleukin-18, TLR2 and TLR4 as wel as in the protein levels of COX-2, ICAM-1 and iNOS was found in the model group (both P<0.05). However, bone marrow mesenchymal stem cel transplantation attenuated this ischemia/reperfusion-induced increase in the expression of the above-mentioned factors (P<0.05). Furthermore, the effects of bone marrow mesenchymal stem cel transplantation were further augmented by pretreatment with emodin in a dose-dependent manner. These findings suggest that emodin can enhance the protective effects of bone marrow mesenchymal stem cel s on renal ischemia/reperfusion injury.

Objective To observe the clinical effects of treating chronic type B hepatitis with Gankang Granule combined with poly I-C and immune ribonucleic acid. Methods A total of 100 cases of chronic type B hepatitis were randomly recruited into a control group and a treatment group, 50 cases in each group. The control group was treated with poly I-C and immune ribonucleic acid, while the treatment group was treated with Gankang Granule on the basis of the control group. Results Symptoms in both groups were improved. 23 eases in the treatment group showed negative value of HBeAg,contrasting to 13 cases in the control group. 38 cases in the treatment group turned to be negative value of HBV- DNA, higher than the number of 23 cases in the control group. The treatment group demonstrated a significantly better therapeutic results than the control group (χ2 value was 6.267 and 6.345 respectively, both P＜0.05). Conclusion Gankang Granule combined with poly I-C and immune ribonucleic acid can obviously improve hepatic functions and symptoms of chronic type B hepatitis,shorten the course of disease, and increase the rate of negative value of HBeAg and HBV- DNA.

Adult ; Female ; Foreign Bodies ; surgery ; Humans ; Neck ; Oropharynx ; surgery

The study intended to evaluate the atherosclerotic plaque burden and composition among symptomatic patients with and without type 2 diabetes mellitus.Total 262 symptomatic patients, including 79 with type 2 diabetes and 183 without, underwent multislice computed tomography coronary angiography.The extent of coronary atherosclerosis and 3 plaque types were studied.Patients with diabetes showed more diseased coronary segments ( P ＜ 0.01 ) and more nonobstructive segments ( P ＜ 0.05 ) than non diabetic patients.Compared to non diabetic patients,diabetic patients had a higher number of coronary segments with non-calcified ( P = 0.005 ) and calcified ( P = 0.016 ) plaques, but not for mixed plaques.The results indicate that type 2 diabetic patients have higher coronary plaque burden.

Fluid Therapy ; Humans ; Rehydration Solutions

After signs of risk have been happened in risk management of medical equipment at present, reports are taken step by step. So there is a report not timely, incomplete information, it is difficult to monitor, and many other problems. With the improvement of risk management requirements; the development of the information technology s apply, and increasing sources of information used for risk early warning analysis. This paper analyzes the requirement of risk management, and proposes a total solution of enterprise risk early warning based on EAI. It will make managers accurately and fully grasp the risks, find risk signs timely, speed up the response to risk.
Materials Management, Hospital ; Risk Management

China ; Female ; Humans ; Neonatology ; ethics ; trends