Objective To analysis the infective case of Ureaplasma urealyticum(Uu)in women pregnancy system,in order to get evidence from medicine sensitive test in UU infection case.Method Use fluorescent quantitative PCR(FQ-PCR)to detect,then provide the medicine according UU-DNA value.After half month,apply the pills the patients stop medicine for 10 days to examine culture and sensitivity test.The positive patients is applied the medicine for half month,examine the UU-DNA after stopping medicine 10 days.Results After one treatment course,51.6% patients turn into negative in culture test.48.4% positive patients turn into negative after one medicine treatment course according to medicine sensitive result.Conclusion The FQ-PCR technique with culture and sensitivity test detect and treat infective case of UU combine is useful to clinical practice.

Objective Detect chromosome aberrance(number and construction) in OSCC cell .Methods Cell were treated with colchicines and microsometic fluid, and then were expanded with cold acetic acid and formalized with methyl alcohol. After Giemsa staining, the cell were observed under oil microscope and the chromosome karyotype was analyzed. Results The number of OSCC chromosome is between 63~66, and many type of chromosome contruction is aberrant, chromosome break and monocase of chromosome break. The number change is appear in increasing of NO 1、7、16、19、20 and lose in NO 6、9、10、18、21、22, the constructing change in NO 1、2、4、11. Conclusion Analysising chromosome aberrance will be useful in location in chromosome for relative oncogene and suppressor gene.

Rifaximin as a representative of the non-absorbable antibiotics,has special effects and wide application prospects in treatments of acute intestinal tract infections,irritable bowel syndrome,inflammatory bowel disease,diverticulosis of colon,hepatic encephalopathy and so on.This paper reviews the advances on clinical efficacy and safety of rifaximin to provide reference for clinical use.

OBJECTIVE:To study the chemical constituents of Glycyrrhiza pallidiflora.METHOD:IR, 1 H-NMR,13C-NMR,MS and TLC were used to identify conpounds .RESULTS:Five compounds were elucidated as homopterocarpin,β-sitosterol,4＇,7-dimethoxyisoflavone,medicarpin and isoglabrol. CONCLUSION:The 4＇,7-dimethoxyisoflavone was first separated from this plant .

As a new cross disciplinary study, translational medicine is expected to promote modern biomedical research to a new stage. In recent years, establishment of research structure of translational medicine has been completed or initiated in some areas where medicine is comparatively well developed, though this conduct is still at an exploratory stage. Referencing abroad experience,This paper discusses the innovative mechanisms and strategies for organization of traslational medicine with referrence to foreign expericences.

0.05).Conclusion There is no significant correlation between ACE gene polymorphism and type 2 diabetic nephropathy.

To investigate the Th1/Th2 profile in peripheral blood of patients suffering from condyloma acuminatum (CA) with or without genital herpes. The levels of the intracellular cytokines (IFN ? and IL 4) of CD4 + T lymphocytes of peripheral blood were assayed by flow cytometry in 35 patients with CA (among them 15 patients were complicated by genital herpes) and 20 healthy volunteers as controls. The results showed that all the patients with CA had significantly higher percentage of Th2 cells and lower percentage of Th1 cells compared with heathy controls( P

Objective To investigate the clinical diagnostic value of transperineal ultrasound in women in late pregnancy with stress urinary inconti?nence. Method Totally 66 cases of women in late pregnancy were selected,who did not suffer from SUI(groupⅠ),and 54 cases of women in late pregnancy who suffered from SUI(groupⅡ). Another 63 cases of healthy childless women were used as normal control(groupⅢ). Transperineal ultrasound was used to dynamically observe their pelvic floor structure,and the ultrasonic parameters were recorded and analyzed,including the posi?tion of bladder neck in X axis and Y axis((Djx,Dzx,Djy,Dzy)during resting period and tension period,the vesicourethral angle(αj,αz),the Bladder angle(βj,βz). The moving of the bladder neck in X axis(ΔDx=Dzx-Djx)and Y axis(ΔDy=Dzy-Djy),as well as the bladder rotation an?gle(Δβ=βz-βj)were calculated and the movement of the bladder neck(ΔD)was measured,followed by comparative analysis. The threshold val?ues of all ultrasonic parameters were determined by the ROC curve analysis. Results The bladder neck of all three groups were backward during tension period. Compared with groupⅢ,ΔDy,Djx,Dzx obviously decreased in groupⅠand groupⅡ,whileβj,βz,αj increased significantly.ΔDx of groupⅡwas significantly larger than that of groupⅢ(P<0.05);There was significant difference in Djy,Dzy,ΔD,Δβandαz among the three groups(P<0.05);In ROC curve analysis,when the critical value of Djy,Dzy,ΔDy,ΔD,αz andΔβwas-1.75 cm,-1.71 cm,0.25 cm,0.29 cm,131.5° and 3.5° ,their sensitivity was 88.9%,88.9%,72.2%,83.3%,88.9%and 72.2%,and the specificity was 72.2%,81.8%,72.7%, 95.5%,86.3%and 68.2%,respectively. Conclusions The transperineal ultrasound could clearly show the pelvic floor of the women in late preg?nancy,the bladder urethral support structure damage or defect was more serious in the women in late pregnancy who were suffering from SUI,and the determination of the critical values of all ultrasonic parameters helped the screening of SUI in women in late pregnancy.

Objective To evaluate the clinical efficacy of percutaneous vertebroplasty (PVP) for patients with fresh osteoporotic vertebral compression fracture (OVCF).Methods From February 2010 to November 2011,103 patients with fresh OVCF were assigned to receive either PVP or conservative treatment according to their choice or the choice of surgeons.There were no significant differences between the 2 groups regarding general clinical data (P ＞ 0.05).The pain was scored at pre-treatment,1,4,12,24 and 48 weeks post-treatment in all the patients.The vertebral re-fractures were recorded in both groups at follow-ups.The 2 groups were compared in terms of postoperative pain relief and risk of re-fracture.Results The overall pain relief at 1,4 and 12 post-treatment in the PVP group was significantly greater than in the conservative treatment group (P ＜ 0.05).The pain relief at night at 1,4 and 12 post-treatment was significantly greater in the PVP group than in the conservative treatment group (P ＜ 0.05).At one year post-treatment,7 vertebral re-fractures were observed in the PVP group (18.4％,7/38) and 12 ones in the conservative treatment group (20.3％,12/59),with no significant difference between the 2 groups in the risk of re-fracture (Hazard ratio =0.909,95％ CI:O.36 ～ 2.29,P =0.841).Conclusion Compared with conservative treatment,PVP may significantly reduce the pain for patients with fresh OVCF but does not increase the risk of vertebral re-fracture.