Objective A pronunciation aid device had been made by using dental prosthodontic method for the treatment of pronunciation disorder, which is caused by movement dysfunction because of defect of soft palate tissues in cleft lip and palate patients.Methods According to the defect condition in the mouth, two types of pronunciation aid devices had been produced regularly by using maxillary impression, plaster casting and thermoplastic resin materials and so on. Results In the first group of cases, after 3 patients were wearing soft palate movement pronunciation aid device, and then they were given pronunciation training, it is found that their language clearances degrees had been promoted obviously. In the second group of cases, 2 patients were wearing naso-pharynx cavity closing pronunciation aid device, it is found that their nasal sound and nasal leakage were disappeared. And in the same time we gave patients pronunciation training, and after one year, their language clearances degrees were found to be more obviously increased than before.Conclusions Naso-pharynx cavity closing pronunciation aid device and soft palate movement pronunciation aid device are an effective non-surgical treatment methods for the treatment of naso-pharynx cavity closing dysfunction and soft palate movement dysfunction.

Objective To observe the different efficacy of combination of inhaled ipratropium bromide and salbutamol and inhaling the two drugs separately. Methods Sixty -five patients with COPD were divided into 3 groups,and treated with different drugs. We observed the lung function FEV1 , the improvement of symptoms and side - effects. Results The FEV_1 and improvement of symptoms in combination group were significantly better than those in seperatin group (P

Objective To explore the effect of active resistance exercise therapy on patients with chronic neck pain. Methods 39 femalepatients with neck pain more than 6 months were recruited in treatment group and received active resistance exercise therapy. 21 healthywomen were recruited in control group without any treatment. They were assessed with cervical curve (C2-7 Cobb's angle), CT attenuationvalue of cervical back muscle, neck muscular strength and endurance and visual analog scale (VAS) before and 12 months after treatment.Results Compared with the control group, the cervical curve of the treatment group was obviously less (P<0.05) and there was no significantdifference pre- and post-treatment P>0.05). The CT attenuation value of cervical back muscle was obviously less in the elder controlsthan in the middle aged ones (P<0.05); and was obviously less in the treatment group than in the controls (P<0.05), and not improved aftertreatment (P>0.05). Compared with the control group, neck muscular strength and endurance of the treatment group were obviously less (P<0.05), and improved after treatment (P<0.05). The score of VAS lowered 1 and 12 months after treatment (P<0.05). Conclusion Active resistanceexercise therapy can obviously improve neck muscular strength and endurance and relieve neck pain.

Objective To investigate the relationship between the pedicle and the transverse process in the thoracic and lumbar verte-brae. Methods 111antertior-posterior images of the lumbar vertebra and 111antertior-posterior images of the thoracic vertebra were chosen and lines were drawn between two pedicle centers of the same segment. The transverse process was divided into 4 equal parts by horizontal lines. The corresponding study was performed on the relationship between the pedicle and the transverse pro cess. Results Most of the T1～T2 pedicles corresponded to the midline of the transverse process. A large number of the T3～T11 pedicles corresponded to the upper 1/3 of the transverse process and the others corresponded to the upper margin, upper 1/4 or the midline of the transverse process. Most of the T12 pedicles corresponded to the upper margin of the transverse process. A large number of the L1, L2 and L5 pedicles corresponded to the upper 1/3 of the transverse process. A large number of the L3 and L4 pedicles corresponded to the midline of the transverse process. Conclusion The thoracic and lumbar pedicles have a multiform corresponding relationship with the transverse process.

College students' employment viewpoint has transferred ultimately from traditional"government-planning assignment" to modern job-seeking mechanism of "two way choice and independent option".Recently,medical college has reformed clinical teaching in 5-years program.But some problems still exist in clinical teaching reflected from the employment situation of medical graduates and the evaluation of recruiting employers.Some work can be done to solve problems existing in medical students' employment.It is an important issue in adapting social requirement through reforming the model of clinical teaching and arranging the period of clinical training reasonably.

With the development of social education,the examination system becomes standardized.The fairness of test paper evaluation,which is a last procedure,becomes more and more important.Aiming at the shortcomings of the existing test paper evaluation,educator should pay more attention and take many effective measures to form good response mechanism in order to embody the fairness about test paper evaluation and give play to the initiative.

The characteristics of medical and health literature novel assessment in institutions of armed forces were described from the secrecy of projects for literature novelty assessment , the limitations of consignee institution , and the non-profitability of literature novelty assessment agency .The major problems of medical and health literature novel assessment in institutions of armed forces were elaborated in terms of the literacy, instability, competency and knowledge limitation of literature novel assessment staff with suggestions put forward for their solution such as strengthening the construction of talent team, joint development and sharing of resources.

The guidelines for the diagnosis and treatment of acute pancreatitis are the important reference for clinicians in treating acute pan-creatitis,especially severe acute pancreatitis (SAP).However,currently there is much discrepancy on the opinion and practice in China, which affects the treatment outcome and cure rate of this disease.Clinical focuses are described in terms of the diagnostic criteria and treat-ment for SAP,with the hope of initiating reflection and discussion on the clinical diagnosis and treatment of SAP.

That provincial hospital hosting the local hospital is an important measure to deepening the reform of medical and health system.Advanced hospital management mechanism and excellent technical experts were gradually introduced into the local hospital to establish South Hubei healthcare alliance,and form province-city-county healthcare alliance.In this way,high quality management,manpower and technology resource sink,overall medical technology level achieves good breakthrough.This promotes the rapid development of healthcare alliance member hospitals in the region.

Interleukin-22 (IL-22) is a new kind of eytokine discovered in 2000. The major sources of IL-22 are activated T1 -cells and NK-cells. Tissue cells at outer body barriers, i.e. of the skin, kidney, the di-gestive and respiratory systems all highly express IL-22R or respond to IL-22. IL-22 functions by promoting the anti-microbial defense, inducing phase reactants, protecting against damage and enhancing natural immu-nity. Furthermore, IL-22 mediates the proliferation, differentiation and apoptesis in cancer cells, that gives us a new idea about tumor therapy.