Thirty-one cases of infant respiratory tract infection were treated by no-pain health-care Tuina plus medicated bath. Since the therapeutic effects were satisfactory, so parents and infants are willing to accept.

Objective To study the value of routine laboratory examinations, symptoms and soluble IL-2 receptor (sIL-2R) in the flare-prediction on systemic lupus erythematosus(SLE). Methods A prospective study was performed in 106 outpatients with SLE and the patients′ conditions were assessed according to Systemic Lupus Erythematosus Disease Activity Index(SLEDAI). Patients were asked to visit at no longer than 3-month interval. All patients were followed-up for 6 to 18 months. At each visit, laboratory examinations, symptoms, disease activity, as well as the changes in the treatment were recorded according to the protocol. The values of these parameters in flare-prediction were comprehensively assessed based on their frequency and time respectively when they became abnormal before the disease flare. Results Among the 106 patients, the disease activity of 67 cases were in remission and satisfied the prospective study criteria of the SLE flare. Thirty-one flares in 29 patients were observed. The frequency of flare was 0.44/patient/year. Comprehensively the most valuable predictor of those parameters was anti-dsDNA antibody, followed by complement components, sIL-2R, erythrocyte sedimentation rate(ESR), complete blood count, urine analysis, fatigue, mucous membrane ulceration, new rashes and alopecia. C3 was a better predictor for SLE flares than that of C4 and CH50. Conclusions The flares of SLE could be predicted. Early intervention will help to prevent patients from flare.

In this paper, we studied the effect of total flavones of Hippophae rhamnoides L (TFH) on beating and transmembrane potential of cultured sucking rat cardiac cell. The results indicated that cellular beating rate and beating amplitude were significantly reduced, the action potential duration of 50% and 90% repolarization was sbortened, the slope of phase 4 depolarization was decreased, and other parameters of the action potential showed no significant change. In addition, we also observed that TFH could make the spontaneous abnormal beating of cell change into regular beating. These findings suggested that the mechanism of TFH on cultured cardiac cell might have some relation to antagonizing inward flow of Ca~(2+) and aocelerating the move of k' outward.

Acupuncture Therapy ; Adult ; Diarrhea ; therapy ; Humans ; Male

Acupuncture Therapy ; Adult ; Fatigue ; therapy ; Female ; Humans ; Seasons ; Sleep Wake Disorders ; therapy

Objective To investigate the method and curative effect for the operative treatment of acetabular fractures.Methods Forty-one patients with acetabular fractures were treated operatively from March 2001 to March 2006.All fractures were classified according to the Letournel-Judet classification,22cases were simple fractures and 19 cases were complicated fractures.Kocher-Langenbeck (K-L) approach were adopted in 31 cases (14 cases through osteotomy of greater trochanter additionally),ilioinguinal approach were adopted in 8 cases and anterior combined posterior approach were adopted in 2 cases.Different fractures were fixed by reconstructive plates and screws.Results All the patients were followed up for 16-36 (24.31 ± 5.31 ) months.According to the reduction criteria of Matta radiography,there were 27 cases with anatomic reduction,8 cases with satisfactory reduction,3 cases with poor reduction and 3 cases with joint contour reduction.According to the Merle D' Aubigne clinical criteria for joint functions,14 cases showed excellent results,18 cases were good,5 cases were fair and 4 cases were poor,and the excellent-good rate was 78%( 32/41 ).Necrosis of the femoral head was found in 3 cases,heterotopic ossification in 4 cases,traumatic arthritis in 3 cases,sciatic nerve injury in 4 cases,femoral nerve injury in 1 case,all the nerve injury recovered in 6 months.Lower extremity deep venous thrombosis in 3 cases,all of them were recovered by given anticoagulation.No death,infection or nonunion were found.Conclusions K-L approach or ilioinguinal approach are adopted in the most of the operative treatment of acetabular fractures.Dual reconstructive plates or single.reconstructive plate combine lag screws can fix solid.It can make hip to do early exercise.

Objective To investigate the clinical effects of Losartan on hemorrheology and left heart function in essential hypertensive patients.Methods 43 essential hypertensive patients were treated with Losartan,50 ms/d～100 ms/d for twelve to seventeen months.20 essential hypertensive patients were treated with Fu Fang Jiang Ya Pian as control group.Then the changes of hemorrheology indexes and left heart function were tested in both groups.Results After the treatment with Losartan the blood pressure reduced effectively(P＜0.001),the whole blood low shear rate hyperviacoSity(ηb),plasma viscosity,AI,whole blood low shear rate reduced viscosity,erythrocyte electrophoresis,Fib reduced obviously(P＜0.01),but the control group had not statistical significance(P＞0.05)before and after treatment.The whole blood high shear rate hyperviscesity,whole blood high shear rate reduced viscosity,Hct,RRI reduced too(P＞0.05),but there was no statistical significance.LVM(P＜0.01)and LVMI(P＜0.05)were obviously reduced,E/A was increased(P＜0.01),IRT(P＜0.05)was shorten (P＜0.05),while the cardiac diastole function improved effectively.The significant differences were not observed in the control group pre and pest treatment(P＞0.05).Condusion Losartan can effectively reduce blood pressure.At the same time,it improves RBC deformation capability,reduce erythrecyte aggregation,Fib,Hct of essential hypertensive patients,and reduce blood viscosity.Losartan can also reduce myocardial hypertrophy,heart weight,and improve heart function.

Purpose To summarize the CT features and clinical characteristics of atypical primary fallopian tube cancer (PCFT) and ovarian cystadenocarcinoma (OCA), in order to improved the diagnosis. Materials and Methods CT findings and clinical data of 12 patients with atypical PCFT (PCFT group) and 20 patients with OCA (OCA group) were retrospectively studied. All patients were confirmed by pathology. Serum CA125 level, clinical characteristics and CT features of two groups were compared. Results Serum CA125 level of PCFT group and OCA group were (486.13±23.89) U/ml and (1606.94±62.86) U/ml, respectively. There was statistic difference between the two groups (P<0.01). There was significant differences on vaginal bleeding and vaginal discharge between the two groups (P<0.01). There were 4 cases with solid mass, 8 cases with cystic solid mass in PCFT group. And in OCA group, 16 cases with cystic solid mass and 4 cases with cystic mass were revealed, which showed statistic differences between the two groups (P<0.05). Some other findings also showed statistic differences including the diameter of ovarian vein on the affected side, the diameter of the round ligament of uterus on the affected side, tumor volume, and CT values of the mass in venous phase and delay phase (P<0.05 or P<0.01). However, there were no statistic significance in the size of metastatic lymph nodes, the mean CT value of the mass on plain scan and in the arterial phase (P>0.05). Conclusion Clinical findings of serum CA125 level, vaginal bleeding, and vaginal discharge combine with imaging findings of diameter of the ovarian vein in the affected side, diameter of ipsilateral round ligament of uterus, tumor volume, CT values of the mass in venous and delay phase would be the key points for differential diagnosis of PCFT and OCA.

Objective To explore the effect of HIPK2 on apoptosis of human kidney tubular epithelial cells (HKC) induced by cisplatin.Methods Apoptosis of HKC cells was induced by cisplatin and the expression of HIPK2 was detected by RT-qPCR and Western blot.Two HIPK2 siRNAs were designed according to gene sequence of HIPK2 and cell lines with HIPK2 knockdown were established through transfecting the HIPK2 siRNAs into HKC cells by liposome.The expression of HIPK2 mRNA and protein was detected by RT-qPCR and Western blot after induced by cisplatin.Then cell apoptosis was detected by Annexin V/PI after the HIPK2-knockdown cells were treated with cisplatin.Moreover,the expression of pro-apoptotic protein bax was detected by Western blot after HIPK2 was knockdown.Results The expression of HIPK2 mRNA and protein was down-regulated obviously on the process of HKC apoptosis which induced by dose-dependent cisplatin (P＜0.05).The transfection of siRNA could significantly reduce the expression of HIPK2 mRNA and protein in HKC (P＜0.05),which promotes the HKC cells apoptosis induced by cisplatin.Conclusions HIPK2 can suppress the HKC cells apoptosis induced by cisplatin.

OBJECTIVE To explore the source resulting in nosocomial infection and main component elements managing and controlling nosocomial infection in order to enhance the administration of nosocomial infection and to raise proposition on standardized administration.METHODS Main component elements resulting in nosocomial infection were investigated by reviewing literature and clinical data,and analyzing hierarchy process of administration.RESULTS Emphasis on the administrative measures of main component elements resulting in nosocomial infection might achieve the aim of preventing and reducing nosocomial infection.CONCLUSIONS Reconstruction of administrative links on nosocomial infection can reduce medical risk and cost.