1.Changes of visual quality after Nd:YAG laser posterior capsular dissection to the patient with after-cataract
International Eye Science 2016;16(11):2071-2074
AIM:To observe and analyze visual quality changes of the patients with posterior capsule opacification ( PCO ) Nd:YAG laser posterior capsular dissection, including the change of the best corrected vision acuity ( BCVA ) , total high- order aberration ( tHOA ) , and the modulation transfer function ( MTF) .
METHODS:In this prospective observational study, 100 cases of patients ( 100 eyes ) with posterior cataract underwent Nd:YAG laser posterior capsular dissection ( posterior capsular diameter dissected was 5mm or higher). The mean age was 65. 52±7. 01 years old. The change of the BCVA was collected. The tHOA and MTF under the 3mm and 5mm pupil diameter were assessed by iTrace respectively before and after Nd:YAG laser posterior capsular dissection.
RESULTS:All the surgery went well without obvious intraoperative and postoperative complications happened. The preoperative BCVA was 0. 451 ± 0. 023 while the postoperative BCVA was 0. 763±0. 025. The difference of BCVA before and after Nd: YAG laser surgery was statistically significant (P<0. 01). At 3mm pupil diameter, the tHOA preoperative was 0. 551 ± 0. 031 while the postoperative tHOA was 0. 214± 0. 011, the differences were significance (P<0. 05). At 3mm pupil diameter while the spatial frequencies ( 5cpd, 10cpd, 15cpd, 20cpd, 25cpd, 30cpd ) respectively, the MTF tHOA value postoperative (0. 644±0. 023, 0. 49±0. 011, 0. 311±0. 015, 0.202±0. 018, 0. 056±0. 027, 0. 041±0. 011) were significantly higher than that preoperative (0. 401±0. 021, 0. 261±0. 026, 0. 179±0. 012, 0. 108±0. 014, 0. 031±0. 016, 0. 022±0. 021), and the difference has statistical significance (P<0. 05). At 5mm pupil diameter, the tHOA preoperative was 0. 752±0.028 while the postoperative tHOA was 0. 361±0. 014, the differences were significance (P<0. 01). At 5mm pupil diameter while the spatial frequencies ( 5cpd, 10cpd, 15cpd, 20cpd, 25cpd, 30cpd) respectively the MTF tHOA value postoperative (0. 426±0. 027, 0. 209±0. 018, 0. 172±0. 013, 0. 116±0. 015, 0. 049±0. 010, 0. 034±0. 014 ) were significantly higher than that preoperative (0. 234±0. 021, 0. 102±0. 019, 0. 088±0. 016, 0. 058±0. 022, 0. 021±0. 014, 0.016 ± 0. 011 ), and the difference had statistical significance (P<0. 05).
CONCLUSION: Patients with posterior capsule opacification ( PCO ) Nd:YAG laser posterior capsular dissection can help improve BCVA, reduce tHOA, increase MTF tHOA values, and significantly improve visual quality of patients.
2.Establishment of three-dimensional finite element model of teeth by CAE software
Mingyong LI ; Bin LI ; Xuanxiang MA
Journal of Practical Stomatology 1996;0(02):-
objective: To generate 3 D model of teeth for finite element method(FEM) analysis by computer. Methods: On the basis of 3 D model created by 3D Max, the 3 D FEM model of teeth was generated by using of CAE software. Boundary condition was set in the part of teeth root with elastic constraint. The elastic modulus was chosen as the modulus of periodontium. Results: Generated right inciser model comprised of 25 386 units and 5 111 nodal points. Conclusion: 3 D FEM model of tooth can be generated by CAE software.
3.Analysis of Risk Factors for Chronic Renal Insufficiency in the Patients with Chronic Heart Failure
Journal of China Medical University 2015;44(8):725-729
Objective To elucidate the related risk factors for the cardiorenal syndrome(CRS),and to provide a reference for the prevention and treatment of CRS. Methods A retrospective study was conducted on 269 patients with chronic heart failure. The subjects were divided into two groups in accordance with estimated glomerular filtration rate(eGFR):patient group(CRS group),eGRF<60 mL/(min ! 1.73 m2)and control group,eGRF≥60 mL/(min!1.73 m2). The patients'general information as well as the related clinical lab indices and accessory examination indi-ces were collected. The risk factors for chronic heart failure and renal insufficiency were analyzed with multivariate logistic regression analysis. Re?sults The prevalence of chronic heart failure patients suffering from CRS was 26.39%. The single factor analysis showed that there were statistically significant differences between the two groups in terms of age,body weight,history of hypertension,and history of diabetes(all P<0.05). Compared to the control group,uric acid,cystatin C,serum urea nitrogen,brain natriuretic peptide,glycosylated hemoglobin,high-sensitivity C-reactive pro-tein,and left ventricular end-diastolic diameter in the CRS group were significantly higher;white blood cell count,hemoglobin,albumin,and left ventricular ejection fraction were significantly lower(all P<0.05). There was no statistically significant difference(P>0.05)between the two groups in regard to white blood cell count,glutamic-pyruvic transaminase,glutamic oxalacetic transaminase,cholesterol,triglycerides,high density lipoprotein,low density lipoprotein,troponin I,serum free triiodothyronine,serum free thyroxine,or thyroid stimulating hormone. Multivariate logis-tic regression analysis showed that older age,low body weight,history of hypertension,history of diabetes,hypoalbuminemia,superb sensitivity C-re-active protein levels,high uric acid,high cystatin C hyperlipidemia,and low ejection fraction were independently associated with the occurrence of CRS. Conclusion Older age,low body weight,history of hypertension,history of diabetes,hypoalbuminemia,high-sensitivity C-reactive protein levels,high uric acid,high cystatin C hyperlipidemia,and low ejection fraction are the high risk factors for CRS in heart failure patients and are inde-pendently associated with the occurrence of CRS. Early identification and control of these risk factors are important for the prevention and treatment of CRS.
4.An Electroencephalogram-driven Personalized Affective Music Player System: Algorithms and Preliminary Implementation.
Journal of Biomedical Engineering 2016;33(1):38-41
In order to monitor the emotional state changes of audience on real-time and to adjust the music playlist, we proposed an algorithm framework of an electroencephalogram (EEG) driven personalized affective music recommendation system based on the portable dry electrode shown in this paper. We also further finished a preliminary implementation on the Android platform. We used a two-dimensional emotional model of arousal and valence as the reference, and mapped the EEG data and the corresponding seed songs to the emotional coordinate quadrant in order to establish the matching relationship. Then, Mel frequency cepstrum coefficients were applied to evaluate the similarity between the seed songs and the songs in music library. In the end, during the music playing state, we used the EEG data to identify the audience's emotional state, and played and adjusted the corresponding song playlist based on the established matching relationship.
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5.Improvement Effect of Prostatitis Capsule on Chronic Non-bacterial Prostatitis Model Rats
Lüping YE ; Degang LI ; Suchun LIU ; Ruqing MA ; Bin BIN
China Pharmacy 2017;28(22):3057-3060
OBJECTIVE:To investigate the improvement effect of Prostatitis capsule on chronic non-bacterial prostatitis(CNP) model rats. METHODS:60 rats were randomly divided into sham operation group (distilled water),model group (distilled wa-ter),Pule'an tablet group(positive control,2 g/kg)and Prostatitis capsule high-dose,medium-dose,low-dose groups(16,8,4 g/kg). Except for sham operation group,other 5 groups were injected Xiaozhiling injection 0.2 mL to reduce CNP model. After 7 d of modeling,they received related medicines,ig,once a day,for 45 d. After 24 h of last administration,prostate lesions were ob-served by eyes and wet quality was weighed. White blood cell(WBC)count and lecithin body(SPL)count were conducted under microscope,and prostate tissue slices were pathologically observed. RESULTS:Compared with sham operation group,prostate showed gray nodules,adhesion in glands and surrounding tissue;wet quality of prostate and WBC,SPL count in prostate tissue were significantly increased(P<0.01);under microscope,there were significant congestion,edema and a variety of inflammatory cell infiltration in prostate interstitial. Compared with model group,gray nodules in prostate in Pule'an tablet group and Prostatitis capsule group were reduced,as well as adhesion degree in prostate and surrounding tissue;wet quality of prostate and WBC,SPL count in prostate tissue were significantly decreased(P<0.01);pathological changes had improved to varying degrees under micro-scope,especially the changes in Prostatitis capsule high-dose group,and prostate tissue only showed mild congestion,edema and little inflammatory cell infiltration. CONCLUSIONS:Prostatitis capsule has a certain improvement effect on CNP model rats.
6.Efficacy of Using a Semiconductor Laser Combined with Short-wave Ultraviolet Rays to Treat Herpes Zoster
Changsi LI ; Yongxin SUN ; Bin LI ; Yuewen MA
Journal of China Medical University 2017;46(2):153-155
Objective To observe the efficacy of using a semiconductor laser combined with short-wave ultraviolet rays(UV)to treat patients with herpes zoster. Methods Forty-two patients with herpes zoster in the Department of Dermatology of our hospital were randomly divided into two groups,with 21 patients per group. Patients in the control group were treated with conventional dermatology drugs and short-wave UV,whereas patients in the observation group were treated with conventional dermatology drugs and a semiconductor laser combined with short-wave UV. Re-sults After treatment for 7 days,the efficacy rate in the control group was 80.95%,whereas that in the observation group was 95.24%. The analge-sia time,scab time,and scab removal time were significantly shorter in the observation group than in the control group(P<0.05). The results of the pain assessment(visual analog scale )showed that the score of the observation group after treatment was significantly lower than that of the con-trol group(P<0.05). Conclusion Therapy involving a semiconductor laser combined with short-wave UV for patients with herpes zoster can be more effective than therapy with only a short-wave UV laser in promoting herpes healing,relieving neuralgia,and improving quality of life.
7.The clinical study on the treatment of peptic ulcer with blood clot and drug intervention in the department of internal medicine
Jinyue LI ; Junyue TAO ; Bin LI ; Zhiming XU ; Yuehong MA
Chinese Journal of Biochemical Pharmaceutics 2017;37(4):432-434
Objective To study the clinical effect of drug intervention on the treatment of peptic ulcer with blood clots in the Department of internal medicine.Methods From 62 cases of peptic ulcer adherent blood clot were randomly divided into study group and control group according to the random number table,31 cases in each group,in each group.The control group was treated with esomeprazole infusion and subsequent oral treatment.The study group was given endoscopic hemostasis and subsequent oral esomeprazole treatment.Compare the two groups of curative effect,treatment profile and treatment before and after the study of the changes in the situation.Results The total effective rate of the study group was 90.32%,which was significantly better than that of the control group(P<0.05),which was significantly better than that of the control group 70.97%.Research group of rebleeding rate and transfer rate of surgery was significantly lower than that of control group(P<0.05),the study group,the time of hemostasis,the time of hospitalization significantly faster than that of the control group(P<0.05),study group medical expenses are significantly less than the control group(P<0.05).The two groups before treatment Blatchford score,Rockall score,SF-36 score no significant difference,after treatment in the two groups of the three scores were compared with those before treatment significantly optimized(P<0.05)study group the score optimization was significantly better than the control group(P<0.05).Conclusion Peptic ulcer adhesion blood clot give endoscopic therapy can greatly enhance the efficacy,reduce bleeding and transfer the risk of surgery,more effectively improve the acute upper digestive tract bleeding symptoms and signs,improve the life quality of the patients.
8.Effect of psychological intervention on functional rehabilitation of femoral supracondylar fractures
Yunyan WANG ; Xianfeng MA ; Changhai ZHANG ; Bin LI ; Mingfu LI
Chinese Journal of Behavioral Medicine and Brain Science 2011;20(7):611-612
Objective Effect of psychological intervention on functional rehabilitation of femoral supracondylar fractures.Methods 84 type C fracture patients according to AO criteria for the diagnosis were collected,and randomly divided into intervention group(n=42)and control group(n=42)according to patient sex,age,fracture condition,cultural degree balanced matching principle.The control group was given conventional treatment and fracture features of health guidance,the intervention group in addition to conventional treatment and rehabilitation guidance.Comprehensive mental intervention applied 4 times on postoperative 3 days,the 2nd,3rd,4th week.Self-anxiety scale and self-depression scale were used before operation and 6th month after operation.Results The anxiety and depression scores in two groups before intervention showed no significant difference P>0.05).6 months after the operation,the anxiety score(41.6±9.4 vs 48.7±8.5)and depression score(40.6±7.6 vs 47.4±9.2)in intervention group apparently decreased than that in control group(P<0.01).Function restoration of knee joint in different effect showed better than control group(u=-2.0591,P<0.05).Conclusion Psychological intervention can effectively promote the functional recovery of patients with femoral supracondylar fractures and promote anxiety and depression mood.
9.Prognostic factors in 339 patients with T2N0M0 colorectal cancer
Bin XU ; Lin YU ; Lizhong ZHAO ; Li ZHANG ; Dongwang MA
Chinese Journal of General Surgery 2016;31(7):553-556
Objective To find T2N0M0 colorectal cancer patients at high risk for relapse or metastasis.Methods From January 1993 to December 2014,339 patients with histologically confirmed stage T2N0M0 primary colorectal cancer treated by radical surgery with complete clinical follow-up data were enrolled into this study.Survival rates were calculated using Kaplan-Meier method,and survival cures were compared using the Log-rank test.Cox proportional hazards model was used to analyze the significant factors defined in univariate test.Results The 5-year and 10-year overall survival rates were 83.0% and 68.9%,respectively.Male gender,old age,lymphovascular involverment,perineural invasion,poor differentiation and invasive micropapillary carcinoma were associated with low cancer-specific survival rates in Kaplan-Meier analysis.Multivariate analyses revealed male gender,old age,lymphovascular involverment,poor differentiation and invasive micropapillary carcinoma as significant independent factors predicting poor prognosis.Conclusions Male gender,old age,lymphovascular involvement,poor differentiation and invasive micropapillary carcinoma are risk factors predicting poor prognosis for T2N0M0 colorectal patients.
10.The diagnostic value of serum prostate specific antigen combined with value of apparent diffusion coefficient in diffusion weighted imaging and magnetic resonance spectroscopy in prostate cancer of prostate specific antigen gray zone
Hao LI ; Xiaodong WANG ; Le GAO ; Bin MA
Chinese Journal of Postgraduates of Medicine 2016;39(3):249-253
Objective To investigate the diagnostic value of prostate specific antigen (PSA) (fPSA, fPSA/tPSA, PSAD) combined with value of apparent diffusion coefficient (ADC) in diffusion weighted imaging (DWI) and magnetic resonance spectroscopy (MRS) in the diagnosis of prostate cancer (PCa) between total PSA (tPSA) 4- 10 μg/L. Methods From December 2013 to 2015 February , 56 elderly male patients with serum tPSA 4-10μg/L were enrolled. Pathological examination confirmed 26 patients with PCa and 30 patients with benign prostatic hyperplasia (BPH). The levels of tPSA and free PSA(fPSA) , fPSA/tPSA, Prostate specific antigen density(PSAD), ADC value according to the DWI, choline(Cho), creatine(Cre) and citrate(Cit) in MRS were analyzed, and ADC, (Cho+Cre)/Cit combined with PSAD and fPSA/tPSA in PCa diagnosis was analyzed by receiver operating characteristic curve (ROC). Results The level of tPSA in PCa group and BPH group had no significant difference (P >0.05), but the levels of fPSA、fPSA/tPSA、prostate volume, PSAD, (Cho+Cre)/Cit, ADC had significant difference:(1.04 ± 0.14) μg/L vs. (1.22 ± 0.34) μg/L, 0.15(0.14- 0.16) vs. 0.17(0.15-0.18), (41.45 ± 5.70) cm3 vs. (48.70 ± 9.97) cm3, 0.17(0.15-0.18) ng/(ml·cm3) vs. 0.16(0.14-0.17) ng/(ml·cm3), 2.22 ± 0.59 vs. 1.17 ± 0.52, 0.98 ± 0.28 vs. 1.39 ± 0.24, P < 0.01 or < 0.05. The area under the curve of (AUC) fPSA/tPSA+PSAD+(Cho+Cre)/Cit、fPSA/tPSA+PSAD+ADC、fPSA/tPSA+PSAD+(Cho+Cre)/Cit+ADC were 0.932, 0.941 and 0.977, and the AUC of fPSA/tPSA+PSAD+(Cho+Cre)/Cit+ADC was the highest. Conclusions PSAD and fPSA/tPSA and the value of ADC in DWI and MRS can be used in diagnosis of PCa.