1.Design and application of self-made water pillow
Modern Clinical Nursing 2014;(7):85-87
Objective To explore the effect of self-made water pillow on absolute bed rest patients.Methods Eight-eight patients were randomly allocated into observation group(n=46)and control group(n=42).The patients in the control group received daily care with conventional cotton pillows which were placed at the compression part, while those in the observation group were treated with newly designed water pillows.Both groups received constant turn-over to avoid pressure sores.The two groups were compared in terms of times of daily turn-over,degree of comfort and rate of skin pressuring red.Results The time of daily turn-over in the observation group was less than that of the control group and the degree of comfort was higher and the rate of skin pressuring red smaller all with statistically significant differences(P<0.05).Conclusion The application of the self-made water pillow can effectively prevent pressure sore,enhance comfort degree of absolute bed rest patients and reduce the workload of nursery.It is simple, economical,convenient and safe.
2.Effects of fluvastatin and Shexiang baoxin pill on expression of 1 lectinlike oxidized low density lipoprotein receptor-1 in a rabbit model of atherosclerosis
Journal of Chongqing Medical University 2008;0(S1):-
Objective:To explore the expression of LOX-1(lectin like oxidizeol low density lipoprotein receptor-1,LOX-1) in aorta of atherosclerotic rabbits and modulating the effect of fluvastatin and Shexiang baoxin pill on the gene and protein expression of LOX-1. Methods:Tirty-two New Zealand white rabbits were randomly divided into four groups: hypercholesterol diet group (fed mth high cholesterol diet),hypercholesterol diet plus Fhevastatin group(fed with high cholesterol diet plus Fhe vastain 25mgl kgld).hypercholesterol diet plus shexiang Bao xin Pill group (fed with high cholesterol diet plus shegxiang Baoxinpill 25mgl kgld).normal diet gwup(fed mith regnlar chow),the protein expression of LOX-1 in aorta of rabbits were examined by immunohistochemsthy,the gene expresswin of LOX-1 in aorte of rabbits were examined by R7-PCK. Results:hypercholesterol diet group(fed with high cholesterol diet),hypercholesterol diet plus fluvastatin group(fed with high cholesterol diet plus Fluvastatin 25mg/kg?d), hypercholesterol diet plus Shexiang baoxin pill group(fed with high cholesterol diet plus Shexiang Baoxin Pill 25mg/kg?d),normal diet group(fed with regular chow),the protein expression of LOX-1 in aorta of rabbits were examined by immunohistochemistry,the gene expression of LOX-1 in aorta of rabbits were examined by RT-PCR. Conclusion:LOX-1 was expressed in rabbit aorta of hypercholesterol diet group and two treatment groups, expression of LOX-1 in two treatment groups both significantly reduced compared with hypercholesterol diet group(P
3.Preparation of IL-2 conjugated immunoliposomes and study on its stability
Journal of Chongqing Medical University 2007;0(08):-
Objective:To search for a simple and rapid method of preparating the IL-2 conjugated immunoliposomes with high conjugate rate.Methods:The IL-2 conjugated immunoliposomes were prepared by Glutaraldhyde,Undecanal or Derivatization.All methods were analyzed and compared.The conjugate rate of IL-2 was determined by Bradford Assay.Centrifugal acceleration experiment served to prove the liposome stability.Results:IL-2 conjugated liposome by shiff’s base through Undecanal didn’t cause IL-2-self or liposme-self inter-cross link,and conjugate rate was high and stability was good.Conclution:Undecanal is suggested to prepare the IL-2 conjugated immunoliposomes for the anaphase cell experiment.
4.Experimental study of Renshen-heche Tablets on tonifying and warming Shen-Yang
Chinese Traditional Patent Medicine 1992;0(11):-
Objective: To study the effect of Resen heche tablets (RSHC) on tonyfing and warming Shen Yang. Methods: The mice model of Shen Yang deficiency was established by injecting hydrocortisone. The body weight, autonomic activity and swimming time in ice water in model mice were observed. The level of superoxide dismutase (SOD) in red cell and lipid peroxide (LPO) in plasma of aged rats were analyzed. The effect on anti stress in mice was examined. Results: RSHC had the remarkable effect to improve body weight and autonomic activity and to prolong swimming time in ice water in model mice, and to increase SOD activity and reduce LPO in blood of aged rats, and to elevate the ability of anti fatigue and anoxic tolerance in mice. Conclusion: RSHC drug has the effect on tonifying and warming Shen Yang; can promote growth, enhance organism activity, elevate the adaptation to circumstances and protect injury from free radicals.
5.Current Situation of Resource and Protection Suggestion about Medicinal Pteridophyta in Guizhou
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(06):-
This article introduced the rich resources of medicinal pteridophyte and its conditions of geographic distribution,morphologic and cultural characteristics.Through the investigation,resource collecting and protection test on the important medicinal pteridophyte in Guzhou,it discussed the conservation and utilization of medicinal pteridophyte medicinal pteridophyte in Guzhou,and provided evidence for resource protection of further reasonable exploitation.
6.Clinical features of sinonasal inverted papilloma with recurrence and malignant transformation.
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2014;28(11):797-800
OBJECTIVE:
To investigate the clinical characteristics, treatment and the effectiveness of sinonasal inverting papilloma with recurrence and malignant transformation.
METHOD:
Retrospective comparative analysis of sinonasal inverting papilloma with recurrence and malignant transformation treated from Jan. 2008 to Oct. 2012 in our hospital.
RESULT:
All the 24 patients with recurrence had the history of sinonasal surgery. Among them, 17 patients recurred once,6 recurred twice and 1 recurred three times. The recurrence time was from 1 month to 14 years after operation. Four patients relapsed within half year after 5 months to 4 years follow-up and the recurrence ratio was 16.7% (4/24). All the 4 patients with recurrence had an operation once again and one of them was given chemoradiotherapy after surgery whose pathological results showed canceration. There was no recurrence among the all of 24 patients followed up until now. Among 5 patients with malignant transformation, 3 patients of them were given radiochemotherapy after surgery. Except 1 patient died of extensive recurrence, 1 received other operation after relapsed twice and 1 lost follow up,all the others were alive without recurrence during 10 months to 4 years.
CONCLUSION
The surgical treatment with completely and positively is the firse choice and an effective management for sinonasal inverting papilloma. To the patients with recurrence on many times and malignant tumors, post-operative radiation or chemotherapy should be considered when needed.
Aged
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Female
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Follow-Up Studies
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Humans
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Male
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Middle Aged
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Nasal Cavity
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Neoplasm Recurrence, Local
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Papilloma, Inverted
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pathology
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Paranasal Sinus Neoplasms
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pathology
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Retrospective Studies
7.Determination of Content and Related Substances of Cefetamet Pivoxil Hydrochloride Tablets by HPLC
China Pharmacist 2015;18(12):2173-2176
Objective:To establish an HPLC method to determine the content and related substances of cefetamet pivoxil hydro-chloride tablets. Methods:A Hypersil ODS2 C18 (250 mm × 4. 6 mm,5 μm) column was used. The mobile phase was 0. 005 mol· L-1 tetrabutylammonium hydroxide solution-acetonitrile (64: 36, adjusting pH to 4. 5 with phosphoric acid). The flow rate was 1. 0 ml·min-1 . The detection wavelength was 232 nm. The column temperature was 30℃ and the injection volume was 10 μl. Results:Cefetamet was completely separated from the related substances. The equation of linear regression was Y=2.29 ×104X-4.30 ×104(r=0. 999 9) and the linear range of cefetamet was 51. 01-510. 07 μg·ml-1 . The average recovery was 99. 60% and RSD was 0. 84%(n=9). Conclusion:The method is simple, accurate and suitable. It can be used for the determination of content and related sub-stances of cefetamet pivoxil hydrochloride tablets.
8.Adiscussion on the postoperative hospital infection and its risks of a heart surgery
Liuyi LI ; Xiaoping ZHU ;
Chinese Journal of Hospital Administration 1996;0(09):-
Observations are made on 1208 postoperative cases and logistic analyses are centered on the risks related to postoperative hospital infections.It is discovered through observations that the rate of hospital infections is 7.5%.The infected parts are mainly the lower respiratory tract and the inci- sion.Logistic analyses of the risks indicate that postoperative hospital infections are related to preopera- tive hospitalization duration,the time span of endotracheal intubation,trachealaryngotomy and the re- tention of pleural drainage,type of operation,operational duration,and postoperative complication. Thesefore,hospitals should look seriously at the postoperative infection risks and take important steps to control them.
9.Mechanism of Impacts of Acupuncture on Genes in the Disorders of Gastrointestinal after Spinal Cord Injury (review)
Chinese Journal of Rehabilitation Theory and Practice 2013;19(10):939-941
The gastrointestinal motility in which clock genes play a role as molecular basis loses rhythm after spinal cord injury. This article reviewed the mechanism of impacts of acupuncture on the genes.
10.Technical progresses of three-dimensional conformal radiotherapy for carcinomas
Journal of Medical Postgraduates 2003;0(07):-
Radiotherapy is one of the three main therapies for carcinomas. The techniques of three dimensional conformal radiotherapy and intensity modulated radiotherapy signify a new age of precise localization, planning and treatment. The author reviewed the development of three dimensional conformal radiotherapy and its related new techniques nowadays.