1.Analysis to current situation of TCM science popularization based on internet
International Journal of Traditional Chinese Medicine 2010;32(6):531-532
By analyzing the current situation of TCM science popularization, We found that internet is serving as the most influential and rapid developing media at present. Therefore, a through excavation and utilization of internet as a tool for TCM science popularization will not only expand TCM science popularization platform, enhance mass foundation, promote mass understanding and recognition of TCM, but also meet the need of TCM self-development.
2.Abscopal effect in tumor treatment
Journal of International Oncology 2008;35(11):826-828
Abscopal effect is for tumor therapy and control of tumor metastasis.it will produce consider-able eignifieance in clinical tumor therapy.The exactly mechanisms of this effect have not been recognized com-pletely so far,and researchers find this effect is associatod with immune system response,espeeiaHy the cell-me-diated immunity.The response of abscopal effect can activate antitumor immunologic response in vivo possibly through antigen releasing and presentation,activation of T cell and natural killer cell,the role of cytokine,in-flammatory reaction,apoptosis,and etc.
3.Clinical research of maintenance therapy for patients with advanced non-small cell lung cancer
Cancer Research and Clinic 2010;22(9):585-588
The first-line chemotherapy with platinum-based regimens for 4 to 6 cycles is a standard care in advanced non-small cell lung cancer (NSCLC). However, for patients who got disease stabilization or maximal response after first line chemotherapy, how to choose safe and efficacy anticancer agents to extend first-line treatment and provide a better clinical benefit is deserving of more concerns currently. In this article,the clinical progress of the chemotherapy and molecular targeted agents as maintenance therapy for patients with advanced NSCLC is reviewed.
4.The robe of transcription factors in genetics mechanism of congenital atrioventricular septal defect
International Journal of Pediatrics 2010;37(6):555-557
Atrioventricular septal defect (AVSD)is a frequently diagnosed congenital heart malformation affecting the atrioventricular valves and septa. Heart transcription factors play fundamental roles in atrioventricular valves development and atrioventricular septa formation. Now cardiac transcription factors ( GATA4, NKX2. 5,TBX5 ,ZIC3)have been identified to involve in the pathogenesis of AVSD in humans. Their abnormal expression or function change may cause atrioventricular valve and septa developmental anomalies. Here we review advances in the understanding of the relationship between these transcription factors and AVSD.
5.The clinical observation and immune adjustment of oxymatrine capsule and acitretin in the treatment of psoriasis
Journal of Chinese Physician 2013;(3):331-333
Objective To investigate the clinical efficiency and immune adjustment of oxymatrine capsule and acitretin in the treatment of psoriasis.Methods Eighty patients with psoriasis were randomly divided into treatment (T) and control (C) groups.The T group took orally oxymatrine one capsule (0.2g) three times a day and one acitretin (10 g) two times a day.The C group only took orally one acitretin (10 g) two times a day.The T and C groups were applied the same drug for external use.Moreover,another 40 normal volunteers were set as normal control group.The peripheral blood T cell subset CD3 +,CD4 +,CD8 +,CD4 +/CD8 + were detected in all the three groups (T,C,and normal) before and after treatment.Results The effective rate was 92.5% in the T group,and 72.5% in the C group with statistical significance (x2 =8.66,P < 0.05).The symptom integral decline index of two groups before and after treatment has statistical significance (t =10.02,P < 0.05).For the peripheral T cell subset CD3 +,CD4+,CD8 +,CD4 +/CD8 + in the T group,a significant difference was found between pretreatment and posttreatment [(57.13 ±8.14)%,(37.62 ±7.97)%,(33.01 ±2.97)%,(1.24 ±0.51)% vs (60.09 ±11.53)%,(43.02±7.67)%,(25.63 ±4.24)%,(1.73 ±0.69)%,t =3.08 ~9.02,P <0.01].However,there was not any statistical significance between pretreatment and posttreatment in the C group (P > 0.05).Conclusions The treatment of common psoriasis combined with oxymatrine capsule and acitretin had a good curative effect and it improved the imbalance of peripheral blood T cell subsets.
6.Postoperative nursing of Moyamoya patients undergoing STA-MTA bypass
Modern Clinical Nursing 2013;(1):50-51
Objective To summarize the experience of nursing Moyamoya patients undergoing STA-MTA bypass.Method The histories of nursing 14 Moyamoya patients undergoing STA-MTA bypass were retrospectively analyzed to summarize the nursing experience.Result The outcomes of all the 14 patients were good.TCD or DSA showed all the anastomosed arteries were patent, and cerebral perfusion was improved.Conclusion The nursing strategies including careful observation of patients,prevention of cerebral hemorrhage and ischemia and enhanced function exercises is critical for patients’rehabilitation.
7.On Individual Differences in Second Language Acquisition
Chinese Journal of Medical Education Research 2002;0(01):-
Individual differences are very important factors that may greatly affect the process of second language acquisition.The learners differ with each other in first language aptitude,motivation,character and even age,which will directly or indirectly influence the final result of his second language acquisition.The study of this topic is of instructive value for the teacher's teaching activity and will also promote the individual learning practice.
8.Clinical analysis on infant malnutrition: an analysis of 63 cases
Chinese Journal of Primary Medicine and Pharmacy 2006;0(08):-
Objective To review and analyze the causes of infant malnutrition and its relation with the way of feed.Methods Infant malnutrition was analysed with the emphasis on pathogeny,the onset month of the birth, its complication and clinical reflection in 63 cases.Results Infant malnutrition occurred in the case with incorrect feeding way:feeding on low protein powdered milk or cereals untimely without considering the supplementary food. Malnutrition easily brought out other kinds of disease.Conclusion It is recommended that infants younger than 5 months should be fed on breast-milk.In case of no breast-milk or short,dairy products are introduced,especially in- fant formula,with adding supplementary food timely.If not so,infant malnutrition occurs.
9.Micropatterning of endothelial cells on poly-dimethylsiloxane flow channel bottom
Journal of Third Military Medical University 2003;0(19):-
Objective To simulate the blood flow features of the susceptible sites of atherosclerosis in vitro.The cell micro-patterning is to be obtained on the bottom of channel for the information about single cell or cell groups.Methods Poly-dimethylsiloxane(PDMS) flow channel and PDMS stamp were fabricated by soft lithography.Fibronectin pattern was formed on chamber bottom by micro-contact printing method and cells selectively attached on fibronectin pattern.Results The PDMS-patterned chamber that possessed favorable optical property and the PDMS stamps with different sizes were obtained.Cells attached on fibronectin pattern presented square array.Conclusion The fabricated methods are quick and simple.The chamber could be used for the advanced real-time investigation of cell mechanical behavior in vitro.
10.The effect of mouse uterine decidualization on NK cell distribution and maturation
Journal of Chongqing Medical University 2003;0(06):-
Objective:To investigate the distribution and regulation of uterine NK cells in mouse uterus during early pregnancy. Methods:Using a unique uNK cell marker,Dolichos biflorus agglutinin (DBA) lectin,to localize NK cells in uterus of normal pregnancy,delayed implantation and artificially induced decidualization. Results:DBA staining is mainly distributed in some vascular endothelial cells during embryo pre-implantation. In D5 of pregnancy after embryo implantation,NK cells were distributed in the stroma of uterine mesometrial pole,with round,immature and small lymphocyte-like cells. During D7 and D8 of pregnancy,the immunostaining results showed that uNK cells were increasingly accumulated in the mesometrial pole of implantation sites,with their morphology changing from small round cells with scattered cytoplasm to large and mature cells with heavy cytoplasmic granules. In the artificially induced decidualization model,the distribution and maturity of NK cells are similar to those of the normal pregnancy in the mouse uteri. Conclusion:The distribution and maturation of uterine NK cells are dependent of uterine decidualization in mouse early pregnancy.