2.The changes and clinical significance of plasma levels of vasoactive substances in patients with congestive heart failure
Ping ZHONG ; Zhiliang LI ; Chaoshu TANG
Chinese Journal of Practical Internal Medicine 2003;0(01):-
Objective To observe the changes of plasma urotensinⅡ(UⅡ)、PAMP(proadrenomedullin N-terminal peptide)and ANP(atrial natriuretic peptide)levels in patients with congestive heart failure (CHF) and to illustrate clinical significance of these changes.Methods 52 patients with CHF and 20 age and gender-matched control subjects were studied.Plasma UⅡ.PAMP and ANP levels of 52 patients with CHF and 20 control subjects were measured by radioimmunoassay.Heart function of all study subjects were mensurated by ultrasound cardiography.Results The plasma UⅡ levels were significantly lower in patients with CHF than that in control subjects [(1.48?1.05) vs (4.28?1.21) pg?mL -1,P
3.Application of modified loop ileostomy in laparoscopic low and super-low radical resection of the rectal cancer with preservation of anus
Daorong WANG ; Qingguo LI ; Dong TANG ; Jie CHEN ; Ping LI
Chinese Journal of Digestive Surgery 2013;(5):362-365
Objective To investigate the value of modified loop ileostomy in laparoscopic low and superlow radical resection of the rectal cancer with reservation of anus.Methods The clinical data of 108 patients who received laparoscopic low and super-low radical resection of rectal cancer with preservation of anus at the Subei Hospital of Jiangsu Province from January 2010 to June 2012 were retrospectively analyzed.Fifty-three patients who received preventive ileostomy were in the ileostomy group,and 55 patients who did not receive preventive ileostomy were in the non-ileostomy group.The operation,incidence of complication and follow-up of the 2 groups were analyzed.All data were analyzed using the t test,chi-square text or Fisher exact test.Results The operation time and blood loss were (185 ± 14)minutes and (31 ± 26)ml in the ileostomy group,and (154 ± 12)minutes and (28 ± 19)ml in the non-ileostomy group,with no significant difference between the 2 groups (t =2.34,1.82,P > 0.05).The time to first flatus,time to liquid diet intake,time to pelvic drainage tube removal,duration of hospital stay,hospital costs were (1.1 ± 0.3) days,(1.1 ± 0.2) days,(5.2 ± 1.0) days,(7.2 ± 1.4) days,(3.0 ± 0.2) ×104 yuan in the ileostomy group,and (4.2 ± 0.6) days,(4.3 ± 0.6) days,(8.4 ± 3.9) days,(12.9 ±4.4)days,(3.8 ±0.7) × 104 yuan in the non-ileostomy group,with significant differences between the 2 groups (t =7.25,28.12,15.34,34.01,7.83,P < 0.05).The incidences of postoperative complications and anastomotic fistula were 5.7% (3/53) and 0 in the ileostomy group,and 21.8% (12/55) and 12.7% (7/55) in the non-ileostomy group,with significant differences between the 2 groups (P < 0.05).Conclusion Modified loop ileostomy in laparoscopic low and super-low radical resection of rectal cancer can effectively reduce the incidence of anastomotic fistula,and helps the recovery of patients.
4.Pay attention to follow-up and monitoring of patients with gastric epithelial dysplasia associated with chronic atrophic gastritis.
Xudong TANG ; Zhenhua LI ; Ping WANG ; Baoshuang LI
Journal of Integrative Medicine 2011;9(1):1-4
Because of the close relationship with stomach cancer and higher rates of carcinoma, gastric epithelial dysplasia associated with chronic atrophic gastritis is considered the most important precancerous lesion of stomach cancer. Due to the absence of recognized treatment methods, periodical follow-up and monitoring were considered an effective method to prevent the occurrence of gastric cancer. Currently, there are numerous areas requiring attention; the authors provide some suggestions on the recognition and key technologies for follow-up and re-examination.
5.Relationship of the variation of leptin receptor gene at 3 057 nucleotide to type 2 diabetes mellitus, obesity and plasma lipid levels
Xiaojun TANG ; Xiane LU ; Suhua ZHANG ; Qifu LI ; Ping LI
Journal of Third Military Medical University 2003;0(15):-
Objective To explore the relationship between the variation of leptin receptor (LR) gene and type 2 diabetes mellitus (DM), obesity and plasma lipid levels. Methods The variation of LR gene exon 20 was detected by polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP) and their relations to type 2 DM and obesity were analyzed. Results The variant frequency at 3 057 nucleotide of G to A transversion was 82.09% for total, 87.33% for DM group, 75.42% for control group. The frequency of AA genotype in DM cases was higher than that in controls, but that of GA genotype was lower, and that of GG in cases did not indicate. According to BMI and WHR level, there was no obvious relationship between gene variations and obesity. There were significant differences between AA genotype and GA genotype about the serum levels of TG, HDL and SBP, DBP. Conclusion At nucleotide 3 057 in LR exon 20, a G to A transversion was found, which may be the susceptibility marker of DM in Chongqing population. An allele was associated with high blood lipid and increased blood pressure.
6.Expression of CD143 and its significance in focal nodular hyperplasia of liver.
Lei SHI ; Li-li JIANG ; Wei-ping LIU ; Yuan TANG
Chinese Journal of Pathology 2006;35(7):421-422
Adenoma, Liver Cell
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metabolism
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pathology
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Adolescent
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Adult
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Child
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Diagnosis, Differential
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Female
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Focal Nodular Hyperplasia
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metabolism
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pathology
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Humans
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Immunohistochemistry
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Liver
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chemistry
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pathology
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Liver Neoplasms
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metabolism
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pathology
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Male
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Middle Aged
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Peptidyl-Dipeptidase A
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biosynthesis
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Young Adult
7.Value of MRS in the differential diagnosis of corpus callosum lesions
Quan LI ; Jia BIAN ; Ping WANG ; Xiao TANG ; Jun LI
Journal of Practical Radiology 2017;33(7):985-987
Objective To explore the value of multivoxel 1H-MRS in the differential diagnosis of corpus callosum lesions.Methods 17 patients with corpus callosum lesions confirmed by clinical or pathological method underwent MRS examination.These patients included 2 cases of lymphoma,4 cases of Marchiafava-Bignami disease,3 cases of glioma, 7 cases of infarction,and 1 case of multiple sclerosis.MRS features of lesions were analyzed.Results 2 cases with corpus callosum lymphoma revealed significantly increased Cho peak, decreased Cr and NAA peak,towering Lip peak.Among 4 cases with Marchiafava-Bignami diseases, 2 cases revealed increased Cho/Cr and decreased NAA/Cr,1 case showed normal,1 case revealed inverted Lac peak.For 3 cases with corpus callosum glioma,NAA peak decreased or disappeared,and Cho peak increased in varying degrees.7 cases with corpus callosum infarction revealed significant inverted Lac peak, and NAA peak decreased in varying degrees.1 case of multiple sclerosis revealed increased Cho peak,decreased NAA peak,and inverted Lac peak during acute period with enhancement,while these features returned normal during inactive period.Conclusion Multivoxel 1H-MRS plays an important role in the differential diagnosis of corpus callosum lesions.
8.Effect of total thyroidectomy on growth and development of children and adolescents.
Hui-Zheng LI ; Ping-Zhang TANG ; Zhen-Gang XU
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2008;43(5):381-382
Adolescent
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Body Height
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Body Weight
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Child
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Female
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Growth and Development
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Humans
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Male
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Papilloma
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surgery
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Thyroid Neoplasms
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surgery
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Thyroidectomy
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adverse effects
9.Application of simulation-based medical education in anesthesia practice course of overseas students
Jun DONG ; Su MIN ; Ping LI ; Xiaoning TANG ; Bo CHENG
Chinese Journal of Medical Education Research 2012;11(2):210-212
Objective To explore advantages of simulation-based medical education for overseas students on training of anesthcsia emergency skills.Methods twenty eight oversea students accepting anesthesia practice course were divided into two groups,each group fourteen.The students of simulation group (group S) were lectured with simulation-based medical education method,while the students of control group (group C) were lectured with tradition education method.Results the practice examination record and satisfaction degree for teaching in group S were both higher than that in group C (P<0.05).Conclusion The simulation-based medical education was better than tradition education method on training of anesthesia emergency skills for oversea students.The simulation-based medical education may raise the learning interest of oversea students obviously,and it is beneficial to students' mastery of practice skills.
10.Effects of different modes of dilution during CVVHDF on the removal of different solutes with different molecular weights
Zhongran CEN ; Zhiliang LI ; Ying TANG ; Zhanguo LIU ; Ping CHANG
Chinese Journal of Emergency Medicine 2014;23(8):857-861
Objective To compare the rates of clearance of different solutes during continuous veno-venous haemodiafiltration (CVVHDF) between pre-dilution and post-dilution.Methods A study in vitro was carried out using model CRRT system with AN69 filter used,which was applied to perform CVVHDF for solutes clearance.The removed amounts of different solutes including potassium ion (K +),creatinine (Cr),vancomycin,insulin,and interleukin-6 (IL-6) were determined in the groups of control (without dilution),pre-dilution and post-dilution during CVVHDF at the same substitution fluid amount.Each group was repeated 4 times (n =4).Results Post-dilution mode increased K +,Cr,vancomycin and insulin clearances significantly.There was no difference in clearance of IL-6 between the pre-and post-dilution groups.In the control group,insulin and IL-6 levels were decreased extremely.Conclusions In general,the rate of clearance using post-dilution of CVVHDF is higher than that using pre-dilution.Among high molecular weight solutes,the difference in clearance is not significant.The control group demonstrates insulin and IL-6 adsorbed by the filter.