Humans ; Neoplasms ; epidemiology ; etiology ; Work Schedule Tolerance

Objective To explore an effective way to improve the quality of life of elderly rheumatoid arthritis (RA) patients by a survey about their present living conditions and analyze the effect of some related factors. Methods This was a descriptive study and convenient sampling survey were adopted. Seventyfive elder patients with RA were investigated with self-developed questionnaire, self-mana-gement scale,family function questionnaire, DAS28, 36 question scale health survey questionnaire (SF-36). The demographic data, elderly RA related knowledge and attitudes, self-management, family function and quality of life were also investigated. Univariate analysis was used to analyze the relationship between the quality of life of elderly RA and the affecting factors. Results The score of SF-36 was (66±12). The SF-36 scores was associated with joint function (r=0.705, P＜0.01 ), and DAS28 (r=-0.712, P＜0.01 ). The SF-36 score was positively associated with the understanding of the deterioration of symptoms, the attitude of patients towards their diseases, satisfactory to the help from their families, the access to medical care and the degree of selfmanagement (r=0.515, 0.485, 0.540, 0.575, 0.545, P＜0.01); while it was negatively associated with the duration of disease course (r=-0.312, P＜0.01 ). In addition, this study also discovered that the quality of life declined with the decline of their economic status, but tended to improve with the increase of education level.Conclusion The life quality of elderly RA patients is not ideal. It is associated with DAS 28 score, the duration of disease course, the understanding of their diseases, the attitude towards their disease, selfmanagement, family support and other facotrs

Objective:To investigate the ultrasonic cleaning machine in the equipment derusting effect of.Methods: Rusty instrument as rust 600, were randomly divided into two groups, experimental group (n=305) and control group (n=295). The first device in according to 1:270 proportion of organic pollutants in multi enzyme cleaning solution good, the experimental group will rust instrument containing stainless steel basket, in according to the proportion of 1:7(water temperature is 60℃) ultrasonic cleaning machine solution rust agent by ultrasound in 10 minutes, with a soft brush to wash; the control group will instrument in the water temperature in 60℃, solution rust agent 1:7 mixing ratio, non constant temperature for 10 minutes using a soft bristle brush. Observe and record the two rust rust indicators, and analysis.Results: The naked eye visual two groups of instruments derusting pass rate was not statistically significant (P<0.05); microscopy (5 times the magnifying glass) experimental group equipment derusting pass rate was significantly higher than that of the control group, there were significant difference between two groups (P<0.001); total flexibility in experimental group was significantly better than the instruments the control group, there were significant difference between two groups (P<0.001).Conclusion: The rusty instrument in a constant temperature of 60℃ plus ultrasonic cleaning descaling effect, improves the equipment clean quality and overall flexibility.

Objective To explore the diagnosis value of CTA on posterior inferior cerebellar artery ( PICA ) aneurysm.Methods The clinical data of 2 patients with PICA aneurysms were analyzed retrospectively .Results Two patients were elderly,acute onset,CT confirmed subarachnoid hemorrhage ,CTA of the first time were negative within 3 h after the onset .After the treatments of preventing cerebral vasospasm , increasing blood volume , protecting brain cells and etc for 3-7 d, one case improved ,one case were invalid .Given CTA examination again then found 3 aneurysms, one case with 2 aneurysms located on the left side of the PICA , accompanying with hydrocephalus ,and the other case with 1 aneurysm located on the left side of the PICA .Two patients obtained a good image evaluation and rich information .Conclusions In view of the particularity of the PICA aneurysms , CTA can be used as the preferred method of examination , which can provide comprehensive imaging data .When CTA examination of the first time is negative , giving CTA again remains an ideal choice after short-term treatment .

Objective:To study the effect and applicability of interventianal therapy using elemene emulsion with gastric carcinoma in the advanced period or relapse after operation.Methods:The embolization of advanced gastric carcinoma in 68 cases via left gastric artery,arteria mesenterica superior and arteria coeliaca in 296 patients using elemene emulsion was done with the method of LEF,ELP pand EAP,the indexes of the angiogram before and after treatment,GI and CT were studied for evaluating the effect with the intervals ranging from 2 to 4 months.The regression rate of carcinoma,the retained time of embolism,the survival stage,the survival rate and histopathology were observed.Results:The survival rate of one year was 63.2%,of two years 29.4% and of three years 7.4%.the average survival time of liver metastasis and non-metastasis was 9.6 and 15.6 months respectively,the regression rate of the carcinoma was 64.8%.These figures were higher than those of other interventional radiology and chemotherapy.Conclusion:The embolism with elemene emulsion is a hopeful method to treat the advanced gastric carcinoma of being unable to operation.

Objective: To analyze the elcctrophysiological and clinical features of 68 common and 9 refractory atrioventricular nodal reentrant tachycardia(AVNRT) cases,thereby to seek safe and effective strategies for the treatment of refractory AVNRT with radiofrequency catheter ablation(RFCA). Methods: Ablation at lower zone is customarily applied in AVNRT,if noneffective,ablation electrode can be gradually moved upward,and radiofrequency energy can be delivered at a midpoint or upper position of His Bundle even with small H waves.The movement of the ablation electrode must be carefully monitored lest His bundle be eroded mistakenly.For those both atrioventricular nodal dual pathways(AVNDP) and atrioventricular accessory pathways(AVAP) are present,we always ablate AVAP first. Results: All 68 common AVNRT cases are simple slow-fast type.Among the 9 cases of refractory AVNRT,2 cases were combined with concealed left postseptal AVAP and concealed right AVAP respectively,while 1 case with atrioventricular nodal three pathways. Conclusion: X-ray anatomical position and intraventricular local mapping should be analyzed for the use of RFCA in refractory AVNRT.Safe and effective mapping should be: small A wave and big V wave,shattered A wave with width≥68 ms,A/V= 0.1-0.25,no H or H≤(0.02?0.03) mV.If lower position and middle position method are noneffective,linear ablation at mid-level of Koch's triangle seems to be a satisfactory alternative,which could avoid complications of atrioventricular block in the upper position ablation.

The test panels are combined for the clinical application according to the principle of the evidence-based medicine, which involves the strict evaluation for the technical performance, diagnostic performance, the result of patients and the economic properties. The guideline for the clinical application of the test panels is established in light of different diagnostic objectives and diseases, providing the best diagnostic service for the physicians and benefiting the patients the most.

Objective To establish an HPLC method for the determination of Chlorogenic acid in Reduping Keli. Methods The determination was performed by HPLC using an YMC ODS-A column (150 mm?4.6 mm, 5 ?m), with mobile phase consisted of acetonitrile-0.2%H_3PO_4 solution (10 : 90) at a flow rate of 1.0 mL/min and a detection wavelength of 327 nm. Results The calibration curve for Chlorogenic acid was linear in the concentration range of 0.0085～0.084 8 mg/mL (r=0.9999). The average recovery was 102.60 % (RSD=1.69%, n =6). Conclusion The method is simple, rapid and applicable for the quality control of Reduping Keli.

The effect of Liu Wei Di Huang Wan(LWDHW)and Rehmannia glutinosa Libosch(RGL)on the immune function of normal and immune-suppressed mice were observed.The results showed that the two medicinal herbs given orally can correct the suppres-sive effect of cyclophosphamide on spleen and thymus weight,serum specific antibodylevel and lymphocyte transformation.They can also improve the phagocytic activity ofperitoneal macrophages and enhance peripheral blood ANAE~+ lymphocyte ratio of mi-ce.Under the same conditions,no obvious effect of LWDHW and RGL on the normalmice was found except that RGL can increase the antibody level of normal mice.Theresults implicate that LWDHW and RGL may have some immunomodulatary effect.

Objective To study the effective interference methods in the patients of Coronary Heart Disease costipation, Methods All patients with Coronary Heart Disease constipation (124 cases) were randomly divided into control group (56 cases) and intervention group (68 cases). By using self -design questionnaire, defecation, meal and sports were evaluated. The patients in the control group were only subjected to routine nursing care, while those in the intervention group to nursing intervention. A period was 7 weeks. Results There was significant difference in defecation, meal and sports between control group and intervention group (P