OBJECTIVE: To investigate the characteristics and general pattern of the adverse drug reactions (ADR) occurred in our hospital. METHODS: A total of 113 ADR cases reported by our hospital in 2008 were analyzed statistically in respect of patients’age and sex, route of administration, dosage form, category of drug, organs and systems involved in ADR and clinical manifestations, etc. RESULTS: The ADR were mainly induced by venous administration (59.29%). Anti-infective drugs dominated the first place on the list of ADR incidence rate (46.90%) followed by TCM preparations (23.01%). The most common manifestation of the ADR was lesion of skin and its appendants(37.17%). CONCLUSION: Great importance should be attached to ADR monitoring to reduce or avoid the occurrence of ADR.

The writer discussed the features of modern relationship between hospitals & patients and the main factor which cause the irreconcilable relationship,and also points out the way of setting up normal relationship between hospitals & patients,furthering the medical reform,normalizing the medical performances,improving the medical service quality,ceteing up and perfecting the related laws and cstrenghening the cultivation and education for medical stndent etc.

Through investigation that the “new network media” has become the partner of youth groups firstly , then this paper discussed the new trend of medical students in new network era , including:paying attention to so-cial trends , thinking of something but without deep thinking;main body values is good , but diversity values show obvious;mental strength weakening presents a variety of forms .In the final analysis how the ideological education in the new era of network breakthrough:to strengthen the construction of campus network , to lead healthy campus culture;establish a network ideological education platform;perfect the network psychological consultation platform , to strengthen medical students′psychological health education; strengthen the student party members and cadres network call .

Artemisinin and its derivatives,which are known as traditional antimalarial drugs,have anticancer activities by inhibiting cell proliferation,inducing apoptosis of tumor cells,and resisting angiogenesis,etc.The activity of inducing apoptosis has become high-light for studies recently.Most scholars believed this activity was obtained by increasing apoptosis-inducing genes(Bax),decreasing anti-apoptosis genes(Survivin,Bcl-2),and regulating two-ways controlling genes,and finally led to the distinctive morphological changes.

Objective:To evaluate the changes in the transverse dimension and the perimeters of the maxillary archs produced by 3 self-ligating appliance systems during the leveling and aligning phases. Methods: 45 patients who had class I skeletal pattern and upper arch crowding 3-6 mm were divided into 3 groups with 15 subjects in every group. The dental casts were analyzed. Results: Statistically significant increases were recorded of all dentoalveolar widths (with the exception of intermolar width measured lingually) and arch perimeters. The increase in arch perimeter showed a significant negative relationship with the individual perimeter of the maxillary arch before treatment. No significant change was found in arch depth. Conclusion: The self-ligating appliance systems produce statistically significant increases in the transverse dentoalveolar width and the perimeter of the maxillary arch during the leveling and aligning phases of treatment.

Objective To investigate the treatment effect and nursing of intravitreous injection of Avastin combined with laser photocoagulation in macular edema caused by vein occlusion.Methods 38 patients(38 macular edema eyes)who had macular edema caused by retinal vein occlusion and accepted intravitreous injection of Avastin combined with laser photocoagulation were selected.Relevant nursing was given before and after the clinical treatment.The visual acuity and retinal thickness were observed and recorded.Results Visual acuity was improved in 36 eyes(94.7％),no change occurred in 2 eyes(5.3％).The thickness of macular was statistically significant compared with before treatment and 2,4,6 weeks after treatment.Conclusions Intravitreous injection of avastin combined with laser photocoagulation is effective on macular edema caused by vein occlusion.Successful treatment is guaranteed by psychological nursing,treatment guidance and health guidance.

Objective To investigate pain heterogeneity in transfusion with different gestures in order to find the best gesture.Methods 80 cases were randomly selected and transfused in the back of the hand with three infusion gestures,which including horizontally laid hand with extended fingers for 20 min as control,horizontally laid hand with relaxed fist for 20 min and horizontally laid hand with fist for 20 min in time sequence.Mark-Gail method was used to assess the pain grade.Results Pain was enhanced in horizontally laid hand with relaxed fist group and horizontally laid hand with fist group when comparing with horizontally laid hand with extended fingers group.And pain was more stronger in horizontally laid hand with fist group than that of horizontally laid hand with relaxed fist group.Conclusions Transfusion with horizontally laid hand combining with extended fingers implicated minimum pain and was the best gesture.Horizontally laid hand with fist flat finger displayed the strongest pain and should be banned.

Using the information metrology's correlation theories and literature measurement method, this article makes statistics of the PBL related research papers in our country's medical education published in 1979-2010 and analyzes this domain's distribution of time, article quantity, authors'units and key word term frequency. We propose that PBL research should be further standardized in the concept aspect and the research technique as well as the discipline involved should be further multiplied in our country.

Erythropoietin (EPO) is a hematopoietic growth factor that has a specific role on erythroid progenitor cells. Recent studies have suggested that EPO has the important neuroprotective effect on brain damage following stroke, and its major mechanisms include neurotrophy, anti-neuronal apoptosis, inhibition of secondary inflammatory response and excitatory amino acid toxicity, maintenance of vascular integrity and promoting angiogenesis, promoting neurogenesis, as well as anti-oxidative stress.

Objective To analyze scanned image optimization based on the multifractal soectrum and image fractal algorithm of 64-slice spiral CT in brain of infant. Methods The image data of Toshiba Aquilion 64-slice CT scanning using 10 mAs were imported to image processing toolboxs of Matlab 7.1. The evaluation of muhifractal spectrum and image denosing were performed, and compared with image quality of conventional low-dose CT using 50 mAs. Results The low-contrast scanned image used 10 mAs is the valueless medical image because of serious noise. Image denoise based on the fractal model had superior characteristic of image detail preserving and better contrast-to-noise ratio(CNR). There existed a group difference in the score of image quality between the rude imaging noise and optimized image based on the muhffraetal spectrum algorithm, though the score was still significantly lower than the normal dosage scanned image(F = 38.85, P < 0.01). The group difference was also manifested the image quality of infants can achieve basieaUy the request of clinical diagnosis by suitable model denoising algorithm. Conclusions Image denoising based on the multifraetal spectrum model can be used on the low-dose and low-contrast CT image optimization. It improved the CNR of the pathological region. The radiation dose of CT scanning in infants would be declined significantly by its further application in the future.