1.Research progress of Chinese Medicine for activating blood and resolving stasis during the regulation of apoptosis gene in spinal cord
Journal of Medical Postgraduates 2014;(7):740-742
Spinal cord injury is a common clinical disease .Cell apoptosis is one of important pathogeneses for spinal cord in-jury, and apoptotic gene plays a very important role in apoptosis on spinal cord injury .Chinese medicine for blood-activating and stasis-dissolving has a good therapeutic effect for spinal cord injury by reducing inflammation , inhibiting apoptosis and improving microcircu-lation.In this paper, we review the research of chinese medicine for activating blood and resolving stasis during the regulation of apoto -sis gene in spinal cord injury based on related documents in the recent five years .
2.Curative effect observation of two kinds of root canal preparation for root canal filling on posterior teeth
Chongqing Medicine 2014;(2):144-146
Objective To evaluate the influence of ProTaper rotary nickel-titanium files root preparation on root canal filling . Methods 30 cases of molars pulpitis and 20 cases of premolars pulpitis or periapical periodontitis were equally divided into two groups .The group A(30 cases) used the ProTaper rotary nickel-titanium files in root canal preparation and the group B (30 cases) adopted the common K files modified step-back technique for root canal preparation .The influence of the root preparation by 2 sets of apparatus on the effect of root canal filling ,and the several aspects of the root canal filling time ,the matching degree of main root canal file and master gutta-percha ,proper filling rate ,postoperative reaction of root canal filling were compared for conducting the e-valuation .Results In the mean root canal filling time of the group A ,average premolar time was 4 min 25 s and molar was 1 min 30 s ,however in the group B ,average premolar was 5 min 30 s and molar was 11 min 41 s ,the time in the group A was greatly short-ened with statistical difference(P<0 .05);the matching degree of main root canal file and master gutta-percha in the group A was 86 .37% for premolar and 88 .89% for molar ,however in the B group ,which was 62 .50% for premolar and 26 .67% for molar ,the matching degree in the group A was greatly improved with statistical difference between them (P<0 .05);the proper filling rate of upper premolar from the X-ray film was 72 .73% in the group A and 70 .83% in the group B ,while which of molar was 80 .0% in the group A and 77 .78% in the group B ,here was no statistical difference between them (P>0 .05);the postoperative pain reaction of root canal filling in both groups were very low and weak without statistical difference .Conclusion The ProTaper rotary nickel-titanium files root preparation can accelerate the root canal filling speed ,improve the matching degree of main root canal files and master gutta-percha and simplify the root-filling therapy procedure .
3.Relationship between thyroid autoantibodies and pregnancy outcome of infertility women after assisted reproductive technology:a systematic review
The Journal of Practical Medicine 2014;(24):4011-4014
Objective To evaluate the relationship between thyroid autoantibodies (ATA)and pregnancy outcome of infertility women after assisted reproductive technology (ART). Methods Relevant studies were identified by searching PubMed, Cochrane library, CNKI and CBM. Results 7 studies were appropriate for meta-analyses and total 4165 patiens were included. Meta analysis shows that the pregnancy rate difference between ATA positive patients and controls have no significance, but the miscarriage rate is greater significant between them. In the meta-analyses, the presence of thyroid antibodies was associated with an increased risk of miscarriage (OR 1.85, 95%CI 1.32~2.59), compared with the absence of thyroid antibodies. Conclusion Pregnant women with thyroid antibodies have an increased risk of complications, especially miscarriage. Future research,should focus on the treatment and thyroid disease on pregnancy outcome.
4.Motor Control and Detection Based on DSP
Jianxiong LI ; Kai ZHANG ; Yibing LI
Chinese Medical Equipment Journal 2004;0(08):-
Objective To present a new method of motor power control in order to realize the precise motor power control of medical equipment. Methods The power control method based on PWM Modulation circuit was proposed by researching the DSP microcontroller TMS320LF240x. Results The test results fully satisfied the design requirements. Conclusion The system has simple structure,good programming,and can use different control algorithms in different applications without the need for change in the external circuit,which is easy to upgrade and meet the needs of special occasions.
5.Laws of acupoint selection of prescriptions for treatment of cervicogenic headache by acupuncture: a modern literature research.
Kai ZHANG ; Yu LIU ; Ge-Li JIANG
Chinese Journal of Integrated Traditional and Western Medicine 2014;34(8):1008-1012
OBJECTIVETo summarize laws of acupoint selection of prescriptions for treatment of cervicogenic headache by acupuncture in modern literature.
METHODSRandomized controlled trials (RCTs) involving acupuncture and moxibustion for treatment of cervicogenic headache were recruited from CBM (1978-2012), VIP (1989-2012), Wanfang Database (1998-2012), CNKI (1979-2012), PubMed (1966-2012), EMbase (1980-2012), and Cochrane Library (Volume 4, 2012). Hand recruitment was also auxiliarily used. The frequency and percentage of common acupoints, the distribution of acupoints along 14 meridians and across each part of the body, the application of specific acupoints, and features of using prescriptions for specific acupoints were statistically described.
RESULTSTotally 37 recruited papers included 42 acupoints and 159 times. Common acupoints covered Fengchi (GB20, 28 times), Jingjiaji (EX-B2, 21 times), Baihui (DU 20, 12 times), Tianzhu (BL9, 1 times), and Ashi point (11 times). Meridians along which acupoints were used mainly covered Foot-shaoyang Gallbladder Meridian, Foot-taiyang Bladder Meridian,and DU meridian. Acupoints were mainly needled from head, neck, and upper limbs. Eight confluence points and luo-connecting point were commonest used as specific acupoints. Acupuncture prescriptions were mostly composed of multiple acupoints. Filliform needle was mainly used in acupuncture methods, followed by electro-acupuncture needle.
CONCLUSIONSModern acupuncture treatment of cervicogenic headache focuses on local specific points and acupoints along meridians. Acupoints were mostly selected from head, neck, and upper limbs by syndrome typing of Chinese medicine.
Acupuncture Points ; Acupuncture Therapy ; methods ; Humans ; Post-Traumatic Headache ; therapy ; Randomized Controlled Trials as Topic
6.General self-efficacy and body dysmorphic disorder of patients with deformities of the maxillofacial region
Chinese Journal of Behavioral Medicine and Brain Science 2013;(6):523-525
Objective To observe the self-efficacy and body image changes of the patients with oral and maxillofacial deformity in pre-and post-operative.Methods 183 patients with oral and maxillofacial deformity and 200 relatives as control group were measured by applying General Self-Efficacy Scale (GSES) of Chinese version and Self-rating Scale of Body Image(SSBI).Postoperative satisfaction degree was scored by applying attitude measurement method of interval scale.Perioperative GSES,SSBI score,and postoperative satisfaction degree were statistically analyzed.Results GSES score (26.79 ± 5.26) was lower than that in control group in preoperative (29.69 ± 5.37),and the difference was statistically significant (P < 0.05).While SSBI score (24.35 ± 8.59) was higher than that in control group(11.04 ± 6.67),and the difference was also statistically significant (P < 0.05).GSES score in postoperative(29.52 ± 3.80) was significantly higher than that in preoperative (P < 0.05).SSBI score in postoperative(18.88 ± 8.19) was significantly higher than that in preoperative (P < 0.05).Postoperative satisfaction was comparatively lower for the patients whose GSES score was higher than 32 and 36 for SSBI in preoperative.Conclusion Oporation can enhance the self-efficacy of patients with oral and maxillofacial deformity and reduce the incidence of patients with body dysmorphic disorder tendency.
7.Prevention and treatment of biliary cardiac reflex in interventional therapy of obstructive jaundice
Chengxue LI ; Kai YANG ; Hong ZHANG
Chinese Journal of Interventional Imaging and Therapy 2017;14(5):283-286
Objective To investigate the prevention and treatment of biliary cardiac reflex in the interventional treatment of obstructive jaundice.Methods Totally 600 patients with obstructive jaundice were selected and divided into group A (without any preventive measures) and group B (with prevention and treatment,injection of atropine),and each group had 300 cases.The incidence of biliary cardiac reflex was observed in two groups.The relationship between the incidence of biliary cardiac reflex and gender,age,ECG abnormalities were analyzed in both groups.The timing of biliary cardiac reflex in interventional surgery was observed.Results The incidence of biliary cardiac reflex in group A was 30.67% (92/300),which was significantly higher than that in group B (22/300,7.33 %),and the difference was statistically significant (x2 =53.06,P<0.05).But there was no significant difference between group A (4/300,1.33%) and group B (0) in the incidence of severe biliary cardiac reflex (x2 =0.45,P>0.05).The incidence of biliary cardiac reflex in both groups was not associated with gender (both Φ=0.022,P>0.05),but the incidence of biliary cardiac reflex in both groups was positively correlated with age and ECG abnormalities (Φage =0.593,0.229,ΦEcG =0.508,0.216,all P<0.05).The incidence of biliary cardiac reflex was the highest in the balloon catheter on the stenosis or occlusion of the expansion in group A (55.43%,51/92) and group B (63.64%,14/22),which were higher than those of in puncture and angiography (all P<0.05).Conclusion Preoperative injection of atropine can effectively prevent the occurrence of biliary cardiac reflex in interventional therapy,meanwhile the patients' own conditions are still need to be attention.
8.The Effect of rh-endostatin on Phenotype of HUVECs at Different Activating Levels
Yan LIU ; Chuangui ZHANG ; Kai LI
Chinese Journal of Clinical Oncology 2009;36(23):1370-1373
Objective: In order to reveal the mechanisms of rh-endostatin and its suppression effect on HUVECs at different activating levels. Methods: Three types of HUVEC were prepared. We detected the ex-pression of CD105 and CD62E on the surface of adhering HUVEC, HUVEC of exponential phase of growth, and HUVEC activated with TNF-alpha. The effect of endostatin on these three types of HUVEC was indicated by the variation in the expression of CD105 and CD62E on the cells. The relationship of the changes in cell markers with the time and the concentration of endostatin was analyzed by SPSS 11.5. Results: The expres-sion of CD105 was correlated with time and dose of endostar in all groups. The expression of CD62E was cor-related with the dose of endostar in HUVEC treated with TNF-α for 24h. Conclusion: Endostatin of a certain dose can inhibit the activation of endothelial cells but it cannot induce cell apoptosis.
9.The efficacy and safety of Prostant ~(TM) in the treatment of chronic prostatitis: a multi-center,randomized,double-blind,placebo-controlled clinical trial
Ningchen LI ; Kai ZHANG ; He XIAO
Chinese Journal of Urology 2001;0(11):-
Objective To evaluate the efficacy and safety of Prostant TM and the patients’ compliance with the treatment of chronic prostatitis of different types. Methods A multi-central,randomized,double-blind,placebo-controlled clinical trial was conducted between June 2002 and December 2002.A total of 125 patients who had been diagnosed as chronic prostatitis and classified according to NIH classification system for prostatitis were divided into two groups: the trial group treated with Prostant TM anally one pill per night for 30 days and the control group given placebo in the same way.The efficacy was evaluated by the NIH chronic prostatitis symptom index (NIH-CPSI) and the WBC count in EPS after the treatment. Results Based on leukocyte and culture results,124 evaluable patients were stratified,with 48 cases of categories Ⅱ(38.7%),45 cases of Ⅲa(36.3%) and 31 cases of Ⅲb(25.0%)with chronic prostatitis.The overall NIH-CPSI scores were averagely reduced by 10.37 points in trial group and 6.65 in control group,and the symptom scores were averagely reduced by 7.34 in trial group and 4.72 in controll group,compared with pre-treatment.Significant differences of reduction were found between the two groups(P
10.Comparison of dissolution of asperosaponin Ⅵ between ultra-micro powder and fine powder of Radix Dipsaci
Chunfeng ZHANG ; Kai LI ; Zhonglin YANG
Chinese Traditional Patent Medicine 1992;0(01):-
AIM:To compare the dissolution of asperosaponin Ⅵ between the ultra-micro powder and the fine powder of Radix Dipsaci.METHODS:The real contents,in vitro release and releasing rate of asperosaponin Ⅵwere determined by HPLC for the ultra-micro powder and the fine powder.RESULTS:In the ultra-micro powder and the ordinary powder,the real content of asperosaponin Ⅵ were 4.87%,4.74%,respectively;in vitro release in 1 h were 48.2 mg/g,47.5 mg/g,respectively;releasing rate parameter T_ 0.9 were 0.23 min,10.41 min,respectively.CONCLUSION:The ultra-micro porphyrization could not influent the real content and in vitro release of asperosaponin Ⅵ in Radix Dipsaci.But it could improve the releasing rate of asperosaponin Ⅵ.