In recent several decades, studies have reported the representation of attention deficit/hyperactivity disorder(ADHD) symptoms could co-morbid in children with autism spectrum disorders(ASD).Compared with the ASD-only group, children with both ADHD and ASD often have a more obvious representation of autism symptom as well as more impaired cognitive functions which could deeply impact on their daily life.There is a brief review of observation and executive functions in ASD children co-morbid ADHD-symptoms.

Objective To observe the efficacy and safety of Compound Kaliziran Tincture combined with 0.1%Mometasone Furoate Cream in the treatment of vitiligo. Methods A total of 120 patients of vitiligo were randomly recruited into a control group (54 cases) and a treatment group (66 cases). The treatment group was treated with compound kaliziran tincture combined with 0.1% mometasone furoate cream for external use, while the control group was treated with topical 0.1% mometasone furoate cream. Both groups received the treatment for one course of three months. Efficacy was assessed at the end of the course. Results The total effective rate was 60.94% and 32.69% in the treatment group and the control group respectively, the difference showing statistical significance (χ2=7.86, P＜0.05) . Conclusion It is safe and effective for compound kaliziran tincture combined with 0.1% mometasone furoate in the treatment of vitiligo with few side effects. The combined therapy is better than single using 0.1% mometasone furoate cream.

Embryonic diapauses mean that early embryos stop developing for some reasons in early pregnant stage. The embryo has dead in uterine cavity, but has not yet discharged. The early clinical manifestation in the areas of traditional Chinese medicine (TCM) can be classified as "pregnant vaginal bleeding", "fetal irritability" and other diseases. Embryonic diapause is a common and difficult gynecologic clinical disease. The prevalence rate which is increasing has become a major reproductive health problem. So the prevention research of embryonic diapauses is very significant. In this paper, through the induction and the summary of Chinese and Western medicine dynamic researches and control methods of embryonic diapauses, detailing a list of pathogenesis and treatment progress in embryonic diapauses. Besides, it can lay the foundation for further study and reducing embryonic diapauses incidence, which can promote reproductive health development.
Fetal Growth Retardation ; etiology ; metabolism ; prevention & control ; psychology ; Humans ; Medicine ; methods ; Medicine, Chinese Traditional ; methods ; Western World

High quality of fertility and pregancy is a specific presentation of family planning in this new historic environment. Our country adopted two-child policy from November, 2013. This symbolized an adjustive stage of reproduction policy in 21st century. It is a major adjustment in the development of national population. As a contry of tremendous population, it is very important to have a high- quality fertility and pregancy for the future of the whole nation, which would improve population quality and restrict development of population. The morbidity of infertility has increased significantly, which brings a huge crisis for national population. Under the guidance of high-quality fertility and pregancy in Chinese medicine theory, improving fertile women's ability of high-quality fertility and pregancy, and follow-up studying is of vital importance for evaluating the treatment of abortion prevention by traditional Chinese medicine and human health of high-quality fertility and pregancy.
Adult ; Blood Circulation ; drug effects ; Drugs, Chinese Herbal ; administration & dosage ; Female ; Follow-Up Studies ; Humans ; Infertility, Female ; drug therapy ; physiopathology ; Kidney ; drug effects ; physiopathology ; Medicine, Chinese Traditional ; Pregnancy ; Pregnancy Outcome ; Reproduction

Objective:To identify the expression of egfp-hri fusion on NIH3T3 cells which is carried by recombinant retrovirus. Methods:The egfp-hri fusion gene was integrated intoNIH3T3 cells by the infection of recombinant viral supernatant from the G418 resistent PA317 cells transfected stably with the plasmid of pLNCX-EGFP-C1-hri. The expression effect of egfp-hri fusion was visualized under the fluorescent microscope, while the expression levels of egfp-hri fusion protein by Western blot. Results:The observation from fluorescent microscope showed the green fluorescent was obviously observed in the cytoplasm , western-blotting showed the expression level of egfp-hri fusion gene increased by 83%and 81%, as compared with those uninfected cells and in the cells infected with empty vector, respectively. Conclusion:The infected NIH3T3 cells can express egfp-hri fusion protein successfully.

Objective To investigate the sensitivity and specificity of different methods for the detection of mycoplasma pneu‐moniae .Methods The serum and throat swab specimens were collected from 199 pneumonia patients .ELISA and real‐time fluores‐cence quantitative polymerase chain reaction (FQ‐PCR) assays were used to detect the serum mycoplasma pneumoniae IgM antibod‐y and DNA .Results Among 199 pneumonia patients ,61 cases were diagnosed as mycoplasma pneumoniae pneumonia according to the diagnosis standard .The sensitivity and specificity of ELISA and FQ‐PCR for detecting mycoplasma pneumoniae were 86 .9%and 96 .7% ,and 78 .3% and 97 .1% ,respectively .Conclusion The sensitivity and specificity of FQ‐PCR for detecting mycoplasma pneumoniae are higher than those of ELISA .

Objective To investigate the changes of blood cell distribution width and D-dimer in patients with chronic obstructive pulmonary disease.Methods 60 cases with chronic obstructive pulmonary disease were selected and according to the course of disease were divided into two groups.30 healthy people were selected to be the control group.MCV, RDW and D-dimer were detected and compared.ResuIts Compared with the control group, MCV and RDW of acute phase group and remission stage group are higher(P<0.05), compared with the remission stage group, MCV and RDW of acute phase group were higher(P<0.05), and RDW and MCV in the acute stage group were positively correlated with the remission stage group (r=0.717, 0.902, P<0.05).Compared with the control group, D-dimer of acute phase group and remission stage group were higher(P<0.05), compared with the remission stage group, D-dimer of acute phase group were higher(P<0.05), and D-dimer in the acute stage group were positively correlated with the remission stage group (r=0.727, P<0.05).ConcIusion The distribution of blood cell distribution width and D-dimer levels in patients with chronic obstructive pulmonary disease in acute stage and remission stage group were increased, and the increasing of patients with chronic obstructive pulmonary disease in the acute stage is more obvious.

Spinal giant cell tumor of bone (GCTB) is a kind of primary benign bone tumors in the spine. It is rich in blood supply,aggressive,and easily recurring and lung metastasizing. So the benign GCTBs of the spine remains a challenge to treat.This article reviews the therapeutic methods in spinal GCTBs,including surgery,radiation therapy,arterial embolization. The treatment for the tumor with lung metastasis is also covered in this review. It is established that En bloc resection with wide margins is the most effective method to spinal GCTBs. To eliminate the residual tumor cells,adjuvant radiation should be done when complete resection is not available. Arterial embolization can be used to treat the huge sacral GCTBs.For those with lung metatasis,they can be controlled by lobectomy and /or chemotherapy.

Objective:To observe the effect of ischemic preconditioning(IP)on hepatocellular apoptosis caused by ischemia-reperfus ion(IR)injury and expression of apoptosis regulatory genes(Survivin,HIF-1?)protein,to explore the protective mechanisms of IP on IR injury in rat liver.Methods:Ninty SD rats were randomly divided into sham operation(SO)group,ischemia-reperfusion(IR)group,ischemic preconditioning(IP)group.In SO group,the hepatoduodenal ligament of rat was only pulled and separated,and then closed the abdomen;IR group subjected to 30 minutes of ischemia;IP group was achieved by ischemia for 5 minutes,followed by reperfusion for 5 minutes before continuous to ischemia for 30 minutes.Ten rats of each group were killed after reperfusion for 2,6,12,24 hours respectively,then liver tissues were taken out.The rats in SO group were killed after operation for 2 hours.To detect the Apotosis index(A)Iand Survivin,HIF-1? protein levels.Results:AI of hepotocytes significantly increased in IR group and IP group than that in SO group(P

Objective To explore the effects of antagonist of angiotensin II(Ang II) receptors on acute pancreatitis(AP) of rats. Methods The Sprague-Dawley rats were divided randomly into normal group, AP group, AP+lower dose of valsartan(5mg/kg) group , AP+higher dose of valsartan(8mg/kg) group, lower dose of valsartan group and higher dose of valsartan group, and each group containing 6 animals. AP animal models were induced by intraperitoneal injection of cerulein. Valsartan was given by intragastric administration. The histopathological changes of pancreas were observed and scored, and the pancreatic edema was evaluated. The levels of plasma amylase (AMY) and pancreatic myeloperoxidase (MPO) were measured. Results Compared with AP group, the pathologic lesions of pancreas and pancreatic edema decreased in the group AP+ valsartan, and the levels of plasma AMY and MPO also reduced. Conclusion Pretreatment with antagonist of angiotensin II receptors in rat acute pancreatitis can markedly reduce pancreatic injury and inflammation.