[Objective]To evaluate the effects of mosapride combined with acupressure at selected time and psychotherapy on constipation-predominant of irritable bowel syndrome.[Methods]A total of 86 patients with constipation-predominant of irritable bowel syndrome(C-BS) randomly divided into two groups:the treatment group(n=43) and the control group(n=43). Every patient in the study was diagnosed C-BS according to Rome II criteria. Patients in control group took mosapride (5mg,tid) and in treatment group acupressure at selected time and psychotherapy were givn besides mosapride.[Results]The total effective rate of the treatment group was 86.0%,which was superior to that of the control group(60.5%)(P

Tanshinone ⅡA has a broad anti-tumor activity and good prospects for clinical application. Its possible mechanism of action involves the regulation of cell cycle, inhibition of cell proliferation, induction of apoptosis, inhibition of tumor invasion, metastasis and inhibition of angiogenesis, and reversal of multidrug resistance. This article reviewed the research progress of anti-tumor effect of tanshinone ⅡA in recent years.

Adult ; Beverages ; Food-Processing Industry ; Hearing Loss, Noise-Induced ; diagnosis ; Humans ; Noise, Occupational ; Occupational Exposure ; Young Adult

Objective To observe the effect of Huanyuan Injection on TNF－ α 、 sIL－ 2R in patients with acute Intracranial hemorrhage.Method Sixty patients were randomly selected and divided into two groups.TNF－ α 、 sIL－ 2R in the blood of the patients were observed before and after therapy with Huanyuan Injection.Result Increasing level of TNF－ α 、 sIL－ 2R could be detected,at the same time,Huayuan Injection could react on the differentiation.Conclusion The effect of Hyanyuan Injection on the levels of TNF－ α 、 sIL－ 2R may show some insight on its therapeutic mechanism for acute hemorrhage stroke.

Adolescent ; Basal Ganglia Diseases ; Calcinosis ; Child ; Female ; Humans ; Pedigree

Animals ; Female ; Hippocampus ; physiology ; Learning ; Long-Term Potentiation ; Male ; Memory ; Mice ; Mice, Inbred Strains ; Pregnancy ; Prenatal Exposure Delayed Effects ; psychology ; Tobacco Smoke Pollution

To apply more precise upper airway modeling and computer fluid dynamic technology, and simulate the upper airways of the fluid velocity, flow field distribution and pressure changes on 1 case of OSAHS patients before and after surgery. At home and abroad, computer fluid dynamic has been applied to research on human airway and predict curative effect before and after operation, but the study of the whole upper airway fluid physics parameter is less within normal people and sick people, more the lack of large sample research. The application of this technology can lay the foundation to establish normal people and sick people upper airways database, formulate normative operation and research process, the quantitative domestic normal population and pathological airway blocking criteria of each plane, develop a handling the precision of simulation software and the curative effect of surgical or medical treatment evaluation system, and open up the new train of thought of OSAHS patients diagnosis and treatment.
Airway Obstruction ; Humans ; Hydrodynamics ; Pharynx ; Pressure ; Sleep Apnea, Obstructive ; diagnosis ; therapy ; Software ; Surgery, Computer-Assisted ; Tomography, X-Ray Computed

OBJECTIVE: To investigate the possible effects of meteorological and environmental factors on allergic rhinitis of children. METHOD: Daily numbers of outpatients consulting general practitioners for AR between Jan 1 2007 and Dec 31 2011 were obtained from the Department of Otolaryngology-Head and Neck Surgery, Shanghai Children Medical Center. Daily maximum, average and minimum temperatures and humidity and wind power for Shanghai of the same 5 years were obtained from the Shanghai Meteorological Office. Air Quality data was provided by the Shanghai Municipal Environmental Protection Monitoring Center on daily SO2, NO2 and PM10, the average of O3 per 8 hours. The data was available as average values derived from the data of 6 state comtrolled monitoring stations distributed across Shanghai. Non-parametric generalized additive model (GAM) was used to analyze the highly non-linear or non-monotonic exposure-response relationship between meteorological and environmental factors and daily outpatient visiting for AR of children. RESULT: The daily numbers of AR children in outpatients department in this study were highest in the average daily temperature 11°C and 21°C. It showed two peak. But as the humidity increased, daily numbers of outpatients of AR children went down, indicating that the higy humidity has protective effect. Every 10 microg/m3 increase of environmental pollutants O3, SO2 and PM10 was linked to 1.95%, 1.19% and 0.33% increase in the number of visitors, respectively, suggesting the air pollution may increase the risk of onset of AR in children. CONCLUSION Meteorological and environmental factors have important effects on AR in children.
Child ; Climate ; Humans ; Humidity ; Rhinitis, Allergic ; etiology ; Temperature ; Weather

Objective To investigate the effect of smoking on large arterial stiffness in patients with essential hypertensive.Methods The aortic,carotid and brachial arterial dimension,intimal-medial thickness were determined by vascular ultrasound technique.Wall cross sectional area and indices of compliance and distensibility were calculated in essential hypertensive patients with smoking(n=75) or without smoking(n=70).Results Hypertensive patients with smoking have increased wall intimal-medial thickness and wall cross sectional area in aortic,carotid and brachial arteries associated with decreased compliance and distensibility.After adjusting for the confounding effects of other variables including Age,BMI,HR,BP,PP,FPG,LDL-C and TG,covariance analysis show smoking remained as predisposed factors for vascular remodeling.Conclusion Smoking aggravates large arterial stiffness in essential hypertensive patients.

[Objective] A randomized control ed trial of traditional Chinese medicine recipe Gujing Tang treatment of premature ejaculation was studied. [Methods] The subjects: 60 patients with premature ejaculation form department of andrologic outpatient, the patients were randomly divided into two groups, Integrated TCM-WM Groups and paroxetine Groups. 30 cases in each group. The Integrated TCM-WM Groups were given Gujing Tang , with paroxetine 10mg, oral, Qd at the same time; The paroxetine groups were given paroxetine 10mg, oral, Qd. Both groups were treated for 3 months. Ejaculation status was evaluated at the timepoint:before treatment, 3 months after treatment,and fol ow-up evaluation of six months after treatment. Evalu-ate parameter including Intravaginal ejaculation latency(IELT) and score of sexual function and Chinese patients with premature ejaculation evaluation -5 (CIPE-5). [Results] After 3 months, both groups were significantly improved, and Integrated TCM-WM Groups improved more significantly. After 6 months of fol ow-up, IELT, motion times and CIPE-5 score of Integrated TCM-WM Groups decreased slightly, but stil had significant difference com-pared to before treatment, and this parameter of Paroxetine groups was returned to the level of baseline, and had no significant difference compared with baseline. [Conclusion] Traditional Chinese medicine Recipe Gujing Tang combined with paroxetine, could not only have rapid onset, enhance patient confidence, improve the psychological state, but also improve the long-term efficacy and avoid recurrent disease after treatment, therefore can achieve ef-fective treatment of premature ejaculation.