Pain and anxiety engender major psychic problems during all phases of treatment for burn patients. Analgesic alone does not allay these problems satisfactorily in these patients. Music therapy, as an important complementary and alternative therapy, has been widely used in multiple medical fields. However, its positive effect on alleviation of pain and anxiety in burn patients is undefined. The objective of this review is to summarize the feasibility, application fields, methods, and the effectiveness of music therapy in allaying pain and anxiety of burn patients during the whole course of treatment.
Anxiety ; therapy ; Burns ; Humans ; Music ; psychology ; Music Therapy ; methods ; Pain ; prevention & control ; Pain Measurement

Objective To investigate the effect of grape procyanidins (GPC) and the regulation of estrogen receptor(ER)on proliferation of human breast cancer(MCF-7)cells. Method MCF-7 cells were cultured with GPC,and divided into six groups: tumor control,high,middle and low dose GPC treated,estrogen antagonist ICI 182. 780 (ICI) control,ICI and GPC combined treated. The proliferation activity level of MCF-7 cells was determined by MTT assay,and the levels of the proliferating cell nuclear antigen (PCNA) and Bax protein were measured by immunohistochemistry method. Results Compared with tumor control group,the level of proliferation activity and the expression of PCNA were significantly decreased in high dose GPC group,while the expression of Bax protein was increased significantly. Compared with high dose GPC group,both the proliferation activity and the PCNA expression were increased,and Bax protein expression decreased significantly in ICI and GPC combined treated group. Conclusion GPC can inhibit the proliferation and induce the apoptosis of human breast cancer cells effectively,and its mechanism is closely related to the regulation of ER.

Modern Chinese course in the Third Military Medical University adhered to post com-petency oriented function for curriculum. It simplified, merged and enhanced the traditional Chinese teach-ing content, to help students to establish a standardized use of language awareness, and establish a sense of cultural identity, which helped medical students learn and appreciate literary works from all countries and famous narrative medical text, improved their moral sentiments, and aroused their empathy and empathy for the response. Under the guidance of the basic theory of spoken language, scientific, systematic, strict oral expression skills and effective doctor-patient communication skills training were carried out for medical stu-dents, so as to cultivate medical students' humanistic spirit and the scientific spirit.

Objective:To observe the inhibition of Chuanhong Baliu Paste on S180 tumor and investigate its apoptotic induction. Methods:60 mice were divided into 5 groups randomly after inoculating S180 tumor. S180-bearing mice were smeared with different dosages of Chuanhong Baliu Paste respectively on skin of right armpit. Model group was administrated with normal sodium and positive group was injected intraperitoneally with Cyclophosphamide (25mg/kg) respectively. The growth inhibition was evaluated; apoptotic cells were detected by DNA agarose gelelectrophoresis and flow cytometry. The expression of Caspase-3 was determined by reverse transcription polymerase chain reaction method. Results:Compared with model group,Chuanhong Baliu Paste could signifi cantly inhibit the growth of S180 (P

[Objective] To search a suitable preoperative intestinal cleansing method for the operation of colon and rectum. [Methods] A randomized controlled trial was applied in 70 cases before colic and rectal operations. Group A was give:n decoction of Folium Cassiae for oral use and saline enema and Group B was treated with saline enema only. The effect on intestinal cleansing was observed during the operation. [Results] In Group A, 26 cases were remarkably effective in intestinal cleansing, 8 effective, and 1 ineffective and 14, 16 and 5 in Group B respectively ( P

This study examined the effects of ursolic acid (UA) on the proliferation and apoptosis of a human ovarian cancer cell line, CAOV3. The CAOV3 cells were cultured in the RPMI 1640 media and treated with different concentrations of UA (0, 10, 20, 40 mumol/L). The proliferation rate of the CAOV3 cells was determined by MTT assay. The apoptosis rate was measured by flow cytometry. ERK activity was detected by immunoprecipitation and the expressions of p-ERK1/2, MKP-1, Bax and Bcl-2 by Western blotting. The results showed that the proliferation rate was significantly decreased in the cells treated with UA as compared with that in the non-treated cells (P<0.05). The intracellular ERK activity and p-ERK1/2 expression were also reduced in the UA-treated cells, while the MKP-1 expression was elevated. Moreover, the apoptosis was found in the CAOV3 cells exposed to UA; the Bax expression was increased and the Bcl-2 expression decreased. The apoptosis rate in the UA-treated cells was much higher than that in the non-treated cells (P<0.05). It is concluded that UA can inhibit the proliferation of CAOV3 cells by suppressing the ERK activity and the expression of p-ERK1/2. And it can also induce the apoptosis of the CAOV3 cells by up-regulating the Bax expression and down-regulating the Bcl-2 expression.

Objective To investigate the application value of three-dimensional power Doppler ultrasonography(3D-PDU) for synovial disease in patients with rheumatoid arthritis(RA). Methods Forty four patients with RA were divided into active (23 cases) and non-active (21 cases) groups. 3D-PDU was used in the wrists to measure the volume of synovium(V) ,vascular index(VI) in synovium.and Doppler spectrum was used to measure synovial artery peak systolic blood flow velocity(PSV) , end diastolic velocity (EDV) and resistance index(RI). Results There were significant differences of the V [(1. 73 0. 73) cm3] and VI (9. 53 6. 11) in the group of active patients compared to the V [(1. 09 0. 76) cm3 , P = 0. 008] and VI [(3.86 4.99), P = 0.000] in the ones of inactive patients. No differences were found for PSV [(16. 8 6. 29) cm/s vs (13. 5 8. 54) cm/s, P = 0. 282] ,EDV [(5. 51 1.77) cm/s vs (5. 03 2. 76) cm/s, P = 0. 539] and RI (0. 66 0. 07 vs 0. 62 0. 08, P = 0. 095)in the comparison of two groups. Conclusions 3D-PDU in determining RA disease activity in patients with synovial medium has a higher application value, VI can be used as an effective indicator to determine the disease activity.

Objective: To analyze chromosome aberrations in bladder transitional cell carcinoma with exfoliated cells, and to evaluate the clinical value of fluorescence in situ hybridization (FISH) in bladder cancer. Methods: FISH was performed using centromeric probes of 3, 7, 17 and locus probe of p16 to examine chromosome aberrations of exfoliated cells of 56 bladder cancer patients and 20 healthy controls to analyze the correlation of chromosome aberration with the pathological features of bladder cancer. The urine cytology of the 56 bladder cancer patients was performed. Results: The rates of aneuploidy of chromosomes 3, 7, and 17 were 58.9%, 39.3%, 58.9% and 75.0% for aberration of p16 in exfoliated cells from the 56 bladder cancer patients. All of the aberrations had no correlation with tumor stage (P>0.05). The aberrations of chromosomes 3, 7, and 17 were significantly correlated with pathological grade (P<0.05). The sensitivity of the 4 chromosome probes for detecting bladder cancer was 80.4%. The detection rate of FISH was obviously higher than that of udne cytology. Conclusion: Chromosome aberration is correlated with the growth of bladder cancer. The detection of FISH has significance for early di-agnosis, prognosis evaluation, and recurrence monitoring of bladder cancer.

For the existing measurement methods of residual voltage which can't turn the power off at peak voltage exactly and simultaneously display waveforms, a new residual voltage detection method is put forward in this paper. First, the zero point of the power supply is detected with zero cross detection circuit and is inputted to a single-chip microcomputer in the form of pulse signal. Secend, when the zero point delays to the peak voltage, the single-chip microcomputer sends control signal to power off the relay. At last, the waveform of the residual voltage is displayed on a principal computer or oscilloscope. The experimental results show that the device designed in this paper can turn the power off at peak voltage and is able to accurately display the voltage waveform immediately after power off and the standard deviation of the residual voltage is less than 0.2 V at exactly one second and later.
Electric Power Supplies ; Equipment Design ; Microcomputers ; Signal Processing, Computer-Assisted

Objective We aimed to study the performance evaluation indicators of central venous pressure (CVP) measuring system for ICU patients in clinical trials and discuss its impact factors.Methods Ac-cording to the performance evaluation indicators of CVP measuring system based on the Delphi method,a form was created to evaluate the continuous CVP monitoring of 197 ICU patients and then the data were collected.A comparative analysis was performed to verify the factors affecting the performance of CVP measuring system.Results The performance of CVP measuring system was affected by the number of threeway switches,vasoactive drugs and positive end-expiratory pressure,the statistical value was 8.577,-6.773and 3.244.There were no statistically significant differences with respect to performance evaluation indicators of CVP measuring system among the patients with different body positions.Conclusions The performance evaluation indicators of CVP measuring sys-tem proves to be feasible and practical by clinical empirical research.Their influencing factors were dis-cussed and they offer a valuable reference for the determination of the performance of CVP measuring sys-tem in clinical practice.