Objective:To explore the application value of MSCT in diagnosis of asymptomatic SPN through DR Chest Physical Examination.Methods: A retrospective analysis of 10 cases of complete image and pathological data of DR, CT, PET/CT confirmed by surgery in asymptomatic patients with SPN.Results: Solitary pulmouary nodules were diagnosed in the 10 patients with DR during chest examination. MSCT scanning indicated 8 cases of pulmonary cancers,one case of tuberculoma and one case of pulmonary inflammatory nodule. In 8 cases of pulmonary cancers, there found lobulation(7cases), spiculate(6cases), pleural invasion sign(5cases), vascular cluster sign(one case), and air-bronchogram(one case). PET/CT scanning testified 8 cases with above medium FDG uptake and 2 cases with mild FDG uptake. Surgical pathology showed 8 cases with lung adenocarcinoma,one case with tuberculoma and one case with granulomatous inflammation.The overall accurate diagnostic rate with MSCT was 100%. Tuberculosis and lung tumors in PET/CT examination showed above moderate FDG uptake, and one case of low FDG uptak was confirmed for pulmonary cancer by histopathology.Conclusion: MSCT is the most valuable imaging equipment in examination of asymptomatic SPN. Fine scanning with image post processing techniques is significant in the diagnosis of begnign and malignant asymptomatic SPN.

Objective:To investigate the value of 64-slice spiral computed tomography (64SCT) in preoperative evaluation of spinal vascular intervention.Methods: Seventeen patients with spinal vascular malformations(SVM) scheduled for spinal vascular interventional therapy in our hospital between January 2012-December 2014 were collected, all received 64-detector spiral CT angiography (64-MDCTA) before surgery, image postprocessing technologies such as volume rendering (VR), maximum intensity projection(MIP) and multiplanar reconstruction(MPR) were applied to conduct three-dimensional reconstruction, the traveling case of spinal cord feeding artery was analyzed and were compared with DSA test results.Results: All of the 17 patients clearly showed the abnormality of spinal cord blood vessels and lesions scope, the SVM classification and lesions scope were exactly the same as that of DSA and intraoperative performance, the coincidence rate was 100%;1 case of patient was not shown fistula, the rest of the patients clearly shown the draining veins around the spinal cord, open position and flow tendency of radiculomedullary artery, the coincidence rates were 100.00%, 94.12%%, 100.00%.Conclusion: 64-MDCTA is important for SVM patients to preoperative evaluation of spinal vascular intervention, for it can fully and accurately reflect the open position and flow tendency of radiculomedullary artery, spatial relationship with the surrounding vessels, spinal cord and vertebral situation, should be widely applied.

AIM: To study the effect of dexamethasone(Dex) on the expression of CD18. METHODS: Quantitative RT-PCR analysis, Northern blotting technique were used to measure the expression of CD18 in U937 cells treated by PMA. RESULTS : Dex could significantly attenuated the effects of PMA in a dose-dependent manner (10 -6 mol/L-10 -10 mol/L). These effects of Dex (10 -7 mol/L) were completely aborted by RU-486 (10 -6 mol/L).CONCLUSION: Dex, via GR, could inhibit CD18 mRNA expression in U937 cells treated by PMA. The effects of Dex might be possibly depended on the counteracting action on the NF-?B.

OBJECTIVETo investigate the curative effect of penile elongation with four differentoperative approaches.

METHODSThrough four different operative approaches (the coronary sulcus ringincision, Y or Z shaped incision or Z shaped incision combined with coronary sulcus ring incision), thepenile skin and fascia were degloved until the penile root. Then the superficial and deep dorsal penilesuspensory ligament were cut off. After electric coagulation of the residue ends, the two-side tissue at thefront of the pubic symphysis was sutured. Then the penile skin and fascia were repositioned and the incisionat the inner and outer plate was closed.

RESULTSThe increased penile static length was (2.9 ± 0.2) cmwith abdominal wall Y incision (12 cases); (3.1 ± 0.3) cm with transabdominal modified Z incision (260 cases); (3.9 ± 0.7) cm with coronary sulcus ring incision (363 cases); (3.4 ± 0.8) cm with combined incision (39 cases). The lengthening effect was significantly different between the coronary ring incision and abdominal wall Y/Z incision (P < 0.05). The postoperative follow-up period was 6 months to 5.5 years without serious complications. Only 3 cases of subcutaneous hematoma occurred with treatment of debridement and drainage. 4 cases with ischemic necrosis at distal penile skin, were treated with debridement, dressing and physiotherapy, leaving no scar.

CONCLUSIONSPenile lengthening surgery are safe and effective through different approaches. The coronal ring incision has the best therapeutic effect.

Bandages ; Debridement ; Drainage ; Electrocoagulation ; Fasciotomy ; Follow-Up Studies ; Humans ; Ligaments ; surgery ; Male ; Necrosis ; surgery ; Organ Size ; Penis ; anatomy & histology ; pathology ; surgery ; Postoperative Period ; Reconstructive Surgical Procedures ; methods ; Skin ; Time Factors