Objective To investigate the effect of percutaneous nephrostolithotomy (PCNL) on patients with different body mass index.Methods The clinical data of 84 patients with kidney stones who were treated with PCNL surgical treatment were enrolled in this study,and they were divided into different groups according to body mass index (BMI),including 16 cases of BMI ＜ 18.5 kg/m2(low BMI group),36 cases of 18.5 kg/m2≤BMI ＜24.0 kg/m2 (normal BMI group),32 cases of BMI≥24.0 kg/m2 (high BMI group),and the curative effect was evaluated.Results Three groups' operation time,multichannel gravel rate,stones clearance,length of hospital stay,blood transfusion rate had no significant difference (P ＞0.05),the incidence of complications in low BMI group [31.25％ (5/16)] was obviously higher than that in normal BMI group [5.56％(2/36)] and high BMI group [9.38％(3/32)],there was significant difference (P ＜ 0.05).Conclusion BMI of PCNL surgery influences on certain effect,low BMI will affect patients with surgery tolerance,cause complications increase,obesity wifl increase the difficulty of the operation.

ObjectiveLamiophlomis rotate is the rare perfumes Tibetan medicine.This article aimed to explore the current research of Lamiophlomis rotate on the base of literature.MethodsEstablish database of researching literature on Lamiophlomis rotate in domestic published between 2000 and 2010.Results Altogether 210 articles distributed in 112 kinds of journals were found.These articles involved with 8 areas of clinical research(113 article),pharmacological research(18 article),component analysis(35 article),preparation process (15 article),breed and cultivation of seeds (4 article),new drug testing (3 article),biological characteristics and drug economics.32 articles gained fimancial assistance from fund.Three articles on breed and cultivation of seeds gained financial assistance from fund,occupying 75.00％ of such research.Conclusion There were few articles published in core journals,besides relatively scattered distribution of researching institute and journals.Studies on breed and cultivation of seeds should be strengthened.

Henoch-Sch(o)nlein purpura(HSP) is one of the most common vasculitides in children with many manifestations including skin purpura,arthritis,abdominal pain and renal involvement.The renal involvement(Henoch-Sch(o)nlein purpura nephritis,HSPN) is the principal cause of morbidity and major risk factor for prognosis in HSP.The paper reviewed the updated treatment strategy for HSPN.Accordingly,steroids,cyclophosphamide,mycophenolate mofetil,mizoribine,cyclosporine,triptolide,angiotensin converting enzyme inhibitors (ACEI) / angiotensin receptor blockers(ARB),plasma apheresis and tonsillectomy are possible indicator for the further therapy of HSPN.Furthermore,prospective randomized controlled treatment studies on children with severe HSPN would be needed.

Most military hospitals lack sufficient support from medical universities and therefore are confronted with a bottle -neck in graduate education. Based on the real conditions of military hospitals, this article introduces the practice and achievement in graduate education in our hospital by expanding the enrollment access, promoting the admission publicity, stressing the disciplinary balance, improving the supervisors′abilities, and enhancing teaching quality. With considerations on the four aspects of supporting strength of scientific research, stratified design of disciplines, construction of teaching quality, and innovation of training modes, it pro-vides some experience in graduate education with a view of giving reference for other military hospitals.

Pectus excavatum and carinatum are the most common deformity of chest wall deformity.To get anatomical deformity correction,beautify,improve physical function and the quality of life are the therapeutic purposes.Among the various clinical research and treatment,non-invasive treatment,which is the trend,is popular in surgeons and patients as well.From clinical experience,combining international and domestic progress of treatment on chest wall deformity,this review discuss the application prospect of non-invasive treatment.

Glioma is the most common type among the malignant brain tumors ,and it accounts for almost half of central nervous system tumors .In addition,one of characters of glioma is easy to relapse .The key to pro-long the patients′survival time is how to choose appropriate treatments after surgical resection .With the develop-ment of medical technology ,precise approaches to treat these tumors are applied ,including radioactive particle im-plantation in brachytherapy and gene therapy .In this paper ,we discuss the status of the two therapies respective-ly,analyzing their superiority and inferiority ,and explore the prospects for the development of combined therapy in order to improve the prognosis of glioma better .

Objective This study was designed to determine the serum CA-Hb 3 level in human colorectal carcinoma and analyze its clinical significance.Methods The level of serum CA-Hb 3 was measured by ELISA in 72 patients with colorectal carcinoma and 36 normal persons as the control group.Results The level of serum CA-Hb 3 in colorectal carcinoma was significantly higher than that of normal control .The level of serum CA-Hb 3 was positively related with tumor size,clinical pathological staging.With progression of clinical pathological staging (Dukes'stage),the level of CA-Hb 3 increased significantly,but its relation to tumor size,age,and sex was not significant.Conclusion Serum CA-Hb 3 assay may be a potentially valuable marker in assessment of pathological staging and judgement of clinical prognosis of colorectal carcinoma.

AIM: To investigate the effect of homocysteine (Hcy) on secretion and expression of interleukin-6 (IL-6), which is a multifunctional proinflammatory cytokine, in cultured rat vascular smooth muscle cells (VSMCs). METHODS: Rat VSMCs were stimulated with Hcy. Cell ELISA was performed to measure the expression of IL-6 protein and semiquantitative RT-PCR was used to dectect the IL-6 mRNA expression. RESULTS: Compared with control, treatment of 0.25 mmol Hcy for 6 h could increase IL-6 production. In addition, Hcy concentration-dependently increased the expression of IL-6 protein in these cells. 0 1 mmol/L, 0 25 mmol/L Hcy increased IL-6 production 1 4-fold and 3 4-fold, respectively Furthermore, RT-PCR analysis demonstrated that homocysteine also enhanced IL-6 mRNA expression in a concentration- and time-dependent manner.CONCLUSION: Homocysteine can induce IL-6 expression in VSMCs and elicit vascular inflammatory response, which may thereby influence the pathogenesis of atherosclerosis.

Analysised the transmission routes of AIDS in hospital,preventive strategies and existing ethic problems.Putting forward the importance of respecting the proper right of AIDS patients and health care workers in the prevention of nosocomial-transmitted HIV.On the basis of scientific study,strengthening the propagating of the knowledge of AIDS in the whole society,respecting the right and statue of AIDS prevention and timely treatment among both patients and health care workers.Respecting their medical treatment right and secrets,detecting HIV of patients on the informed consent.Respecting health care workers' right,providing profession guide and preventive strategies for prevention and control of nosocomial-transmitted AIDS.

Objective To explore the improvement of minocycline on negative symptoms in patients with schizophrenia and its influence on tumor necrosis factor (TNF)-α.Methods Patients with schizophrenia were randomly assigned into two groups.One was olanzapine combined with placebo group (control group, 37 cases).The other was olanzapine combined with minocycline group (treatment group, 200 mg ·d-1,po,bid, 38 cases).Both groups were assessed by the positive and negative syndrome scale (PANSS), the scale for the assessment of negative symptoms (SANS), and also tested the level of TNF-α before and after 12 weeks treatments.Results After 12 weeks treatments, the scores of SANS and PANSS in treatment group were significantly lower than those of control group (P<0.05).The level of TNF-α in treatment group[(6.5±1.3) pg ·mL-1]was significantly lower than that of control group[(7.6±1.8) pg ·mL-1] (P<0.01).Conclusion Minocycline can improve negative symptoms in patients with schizophrenia, and the mechanism may be related to lower the level of TNF-α.