1.Venous thrombosis around internal jugular venous indwelling catheter in hemodialysis patients
Chinese Journal of Nephrology 2009;25(1):1-4
Objective To investigate the prevalence, characteristics and risk factors of superior vena cava and auxiliary branchs thrombosis in hemodialysis patients with internal jugular venous indwelling catheter. Methods A total of 43 cases on hemodialysis (HD) with indwelling short-term catheter in internal jugular vein from June to December in 2007 were enrolled in this study. The clinical data and biochemical indicators were collected to investigate the prevalence, characteristics and risk factors of venous thrombosis around indwelling catheter, such as, superior vena cava and auxiliary branehs in these patients. Results Short-term double Iumen internal jugular venous catheter were placed in 43 HD patients. Different degrees of central vein thrombosis were found in 21 of the 43 HD patients (48.8%). The ratio of thrombosis in jugular vein, brachiocephalic vein, subclavical vein and uperior vena cava was 100% (21/21), 28.6% (6/21), 23.8%(5/21) and 19.0%(4/21), respectively. Ten of the 21 HD patients (47.6%) with central vein thrombosis presented clinical symptoms. Five cases developed edema of the upper extremity, 2 cases had new-onset symptom's pulmonary embolism, and 3 eases developed blood overflowed from inlet port of circum-catheter. The ratio of diabetes mellitus, malignant tumor, the prevalence of increased level of serum lipoprotein a and plasma homocysteic acid were significantly higher in the HD patients with central vein thrombosis than that in those without central vein thrombosis. The odds ratio of diabetes mellitus, malignant tumor, high serum lipoprotein a and high plasma homocysteic acid was 5.758, 4.750, 6.967 and 8.533, respectively. Conclusions The prevalence of central vein thrombosis in HD patients with short-term indwelling catheter in internal jugular vein is quite high. Its clinical symptom is insidious but dangerous. Diabetes mellitus, malignant tumor, high serum lipoprotein a and high plasma homocysteic acid may be the important risk factors of central vein thrombosis in above HD patients.
2.Prevention and treatment for complications of cardiac myxoma excision in 215 cases
Jinsong HAN ; Huishan WANG ; Zongtao YIN ; Hongguang HAN ; Xinmin LI
Chinese Journal of Postgraduates of Medicine 2014;37(14):8-10
Objective To summarize the prevention and treatment experience of complications of cardiac myxoma excision.Methods Cardiac myxoma excision were performed in 215 cases under general anesthesia,cardiopulmonary bypass and cardiac arrest condition.Results Two cases died from severe low cardiac output syndrome which eventually caused multiple organ failure.The remaining 213 cases were cured and discharged.Among 213 cases,low cardiac output syndrome occurred in 35 cases,re-open chest for bleeding was performed in 8 cases,30 cases in arrhythmia (including paroxysmal supraventricular tachycardia in 20 cases and ventricular premature in 10 cases),no vital organs embolism occurred.Follow-up was done to 200 patients for 1-8 years with a follow-up rate of 93.9% (200/213).In 200 cases,1 case died from lung cancer,1 case recurred and was cured after re-operation.The remaining patients had no obvious abnormalities.Conclusion As the particularity of surgical treatment of cardiac myxoma,it is essential to take prevention measures to reduce complications of cardiac myxoma excision in perioperative periods.
3.Studies on the antioxidative activities of extracts from Undaria pinnatifida in vitro
Hua HAN ; Songmei ZHAN ; Yantao HAN ; Jinhan LI ; Chunbo WANG
Chinese Journal of Marine Drugs 1994;0(03):-
Objective The antioxidative activities of extracts from Undaria pinnatifida in vitrowere tested. Methods Using the assay system of peroxide value (POV), diphenyl picryl-hydrazyl (DPPH), the antioxidative activities of various extracts were studied and comparedwith VE and VC. Results Different extracts from Undaria pinnatifida showed antioxidativeactivities, and petroleum ether extract showed the highest free radical scavenging efficiency.Conclusion petroleum ether extract has stronger antioxidative effect than others.
4.The mechanism of protective effects of rotary magnetic field on expe rimental myocardial ischemia in rats
Lisha HAN ; Li HAN ; Yuting MA ; Fang WANG
Chinese Journal of Physical Medicine and Rehabilitation 2003;0(11):-
Objective To study the effect of ro ta ry magnetic field on experimental myocardial ischemia caused by Pitui trin (Pit) injection in rats. MethodsThirty rats with experimental myocardial ischemia induced by intravenous injection of Pit (2U/kg) were divided into three groups: control group, ischemia g roup, rotary magnetic field group. The ST-segment elevated amplitude, T -wave amplitude of ECG, serum NO content, SOD activity and MAD content in the three groups were observed and compared. Results The 30 mT rotary magentic field for 30 min significantly increa sed SOD activity ( P
5.The method of removing breathing baseline in pulse wave signal.
Qingyang HAN ; Bingyu LI ; Xiaodong WANG
Chinese Journal of Medical Instrumentation 2014;38(1):19-22
A method which combines empirical mode decomposition with wavelet transform is employed to remove breathing baseline draft from pulse wave signal. First of all, this method decomposes pulse wave signal into several intrinsic mode functions and judges the intrinsic mode function which contains the information of breathing baseline draft. And then wavelet transform is used to decompose these intrinsic mode functions, and the detail coefficients representing breathing baseline draft are set into zero. At last, the signal is rebuilt. This can realize removing breathing baseline draft. A self-developed measurement device was used to obtain the pulse wave signal for validating, and AC-DC modulation ratio value was adopted to evaluate the effect. The results showed that this method could effectively remove breathing baseline draft from pulse wave signal.
Algorithms
;
Oximetry
;
instrumentation
;
methods
;
Respiration
6.Expression of FHIT gene in cervical carcinoma
Lili HAN ; Yanbing LI ; Huijun WANG
Chinese Journal of Primary Medicine and Pharmacy 2009;16(1):65-67
Objective To investigate the expression of fragile histidine triad (FHIT) gene in cervical carci-noma and relationship with its clinical-pathological implication. Methods The expression of FHIT was detected by immunohistochemistry SP method in 42 cases of cervical carcinoma and 13 cases of adjacent tissue. Results 47.6% (20 of 42) of cases expressed FttIT in the tumor cells,and 92.3% (12 of 13) of cases of the adjacent tissue were present. There was a significant positive correlation between cervical carcinoma and adjacent tissue(P <0.01). The positive rates of FHIT in high and middle desrees of differentiation were significantly higher than that in low degree of differentiation(54.2% vs 38.9%). Tumors with lymph node metastases(45.9%) had loss FHIT protein expression than those without metastasis(60.0%) (P <0.05). The FHIT expression between Ⅰ and Ⅱ stage,the difference was significant(55.0% vs 45.5%) (P < 0.05). Conclusion FHIT gene plays an improtant role in the occurrence and development of cervical carcinoma. It is suggested that FHIT can be a useful marker for predicting invasion and metas-tasis ability of cervical carcinoma.
7.Lavement of balsalazide sodium combined with Xileisan in treatment of ulcerative rectitis
Yang SHI ; Li WANG ; Junguo HAN
Chinese Journal of General Practitioners 2011;10(4):273-274
Thirty patients with ulcerative rectitis were treated by lavement of balsalazide sodium solution combined with Xileisan (test group).The results were compared with those treated by salazosulfapyridine (SASP) suppository (control Ⅰ group, n = 25 ) and those treated by lavement of prednisolone and tinidazole (control Ⅱ group, n =28).The complete remission rate and effective rate were 67% (20/30)and 90% (27/30), 36% (9/25) and 60% (15/25), 68% (19/28) and 86% (24/28) for test group, control Ⅰ group and control Ⅱ group, respectively.The efficacy of test group and control Ⅱ group was better than that of control Ⅰ group (P < 0.05).The least side effects occurred in test group ( P <0.05).The recurrence rates of 3 groups were 20% (4/20), 2/9 and 5/19, respectively.Lavement of balsalazide sodium solution combined with Xileisan is effective for ulcerative rectitis with less side effects.
8.Analysis of risk factors for stroke-associated pneumonia
Jie HAN ; Junping WANG ; Ming LI
Chinese Journal of General Practitioners 2010;09(9):635-637
Clinical data of 595 patients of stroke admitted to the First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning were analyzed retrospectively, 310 (52. 1% ) of them with strokeassociated pneumonia (SAP). Early-onset pneumonia occurred in 225 patients (72.6%), and late-onset pneumonia in 85 (27.4%). Patients with length of hospital-stay equal to or more than two weeks accounted for (113 cases) 50. 3% of those with early-onset pneumonia, whereas patients with length of hospital-stay less than one week (60 cases) accounted for 70. 6% of those with late-onset pneumonia. Age above 65 years ( OR = 1. 037 ), diabetes ( OR = 1. 724), Glasgow coma scores equal to or less than eight ( OR = 0. 098 ),nasal feeding ( OR = 6. 640 ), administration of gastric mucosal protective drugs ( OR = 3. 581 ) and antibiotic prophylaxis ( OR = 2. 433) all were risk factors for SAP.
9.Construction of emergency nurse specialist training evaluation index system model
Yonglan LI ; Shan HAN ; Wenqin WANG
Chinese Journal of Practical Nursing 2013;(1):10-14
Objective To build emergency specialist nurse training evaluation index system model.Methods By Delphi method,21 emergency care specialists participated in the consultation,using the Analytic Hierarchy Process (AHP)to build a hierarchical model,establishing judgment matrix,through statistical calculations to determine the indicators and weight coefficients of the index system of emergency specialist nurse training.Results Four first-level indicators,11 second-level indicators,31 third-level indicators emergency specialist nurse training evaluation system model were established.Conclusions Establishment of emergency nurse specialist training evaluation index system provides an effective method and reference to improve the overall capacity of the emergency specialist nursing team to ensure the quality of training of emergency nurse specialists.
10.The relationship of metabolic syndrome and cardiovascular disease and mortality in maintenance hemodialysis patients
Ling YU ; Han LI ; Shixiang WANG
Chinese Journal of General Practitioners 2013;12(8):625-629
Objective To investigate the potential contributing effects of metabolic syndrome (MS) on cardiovascular events and mortality in maintenance hemodialysis (MHD) patients.Methods According to the diagnostic criteria for MS set by Chinese Diabetes Society,201 subjects undergoing MHD were assigned into MS group(n =78) or non-MS group (n =123),in August 2009.General and laboratory data were collected for cross-sectional analyses,and the participants were followed up for 36 months.Cardiovascular events,cause of death and time were recorded for longitudinal analyses.Results Prevalence of MS was 38.8%.Weight,waist circumference,triglyceride,total cholesterol,low density lipoprotein,fasting glucose level,uric acid and high-sensitivity C-reactive protein were significant higher in MS group compared to non-MS group,but duration of dialysis and high-density lipoprotein were lower (P < 0.05).During the 36 months follow-up,cumulative incidence of cardiovascular events,cardiovascular and all-cause mortality were 41.0% (32/78),19.2% (15/78),28.2% (22/78),in MS group respectively.Those of non-MS group were 22.8% (28/123),10.6% (13/123),17.1% (21/123).There was significant difference between patients with and without MS in cumulative incidence of cardiovascular events (x2 =7.601,P =0.006).There was relationship between the number of metabolic syndrome parameters and cardiovascular events (r =0.236,P =0.001).Kaplan-Meier curves showed the relationship between two groups did not remained statistically significant in cardiovascular and all-cause mortality.Impaired glycometabolism in 5 parameters of MS was a cardiovascular mortality risk factor in MHD patients.Conclusions The prevalence of MS is high in MHD patients.MS is a risk factor of cardiovascular events,but it is not associated with cardiovascular and all-cause 3-year mortality in patients with MHD.