Objective:To discuss the effect of bifid triple viable capsules on plasma D-lactic acid and stool S-IgA in the patients with colorectal cancer after the operation. Methods:Totally 68 cases of patients with colorectal cancer after the operation were selected and divided into the observation group and the control group at random. The patients in the two groups were given enteral nutrition and postoperative routine medical treatment with the treatment course of one week from the third day after the operation. The patients in the observation group were additionally given 620 mg bifid triple viable capsules, twice a day. The occurrence rates of diarrhea and flora imbalance, D-lactic acid in plasma, S-IgA in stool and adverse drug reaction ( ADR) in the two groups were observed and compared after the medical treatment. Results:After the one-week medical treatment, the occurrence rates of diarrhea and flora imbalance in the observation group were much lower than those in the control group (P<0. 05). After the treatment, D-lactic acid in plasma in the two groups was declined, while S-IgA in stool was decreased than that before the treatment, and the changes in the observation group were more notable than those in the control group (P<0. 05 or P<0. 01). No obvious ADR appeared in the two groups during the medical treatment. Conclusion:The application of bifid triple viable capsules in the patients with colorectal cancer after the operation can re-duce D-lactic acid in plasma and ralse S-IgA in stool, which can effectively recover intestinal mucosal barrier function and local immu-nity, and reduce alteration of intestinal flora and occurrence of diarrhea with high security.

Objective To evaluate the clinical efficacy of absolute ethanol combined with histoacryl sclerotherapy in treating high-reflux venous malformation in children.Methods The clinical data of a total of 339 sick children with venous malformation,who were admitted to authors' hospital during the period from April 2009 to April 2014 to receive interventional sclerotherapy under general anesthesia,were retrospectively analyzed.Sclerotherapy with absolute ethanol combined with N-butyl cyanoacrylate (NBCA) was carried out in 137 sick children with high-reflux type venous malformation.The patients were followed up for 6-24 months (mean of 15 months).Results Successful sclerotherapy with absolute ethanol combined with NBCA was achieved in all 137 sick children with high-reflux type venous malformation.Complete cure was obtained in 23 sick children,basic cure in 31 sick children,and effective response (improvement) in 42 sick children;the total effective rate was 70％ (96/137).Ectopic embolization due to reflux of NBCA occurred in one sick child,skin ulceration was seen in 8 sick children and intraoperative transient pulmonary hypertension was observed in 3 sick children.The adverse reaction rate was 8％(12/137).Conclusion For the treatment of high reflux venous malformation in children,sclerotherapy with absolute ethanol plus NBCA is safe and effective,this technique carries low incidence of adverse reactions.(J Intervent Radiol,2017,26:217-220)

The paper describes the major steps taken by Hongze County of Jiangsu Province in reforming the health personnel system. These include: (1)adopting the personnel agent system; (2)implementing the all-personnel appointment system; (3)exploring ways of reforming the executive personnel management system; (4)setting up a flexible mobility system of health technicians; and (5)putting into effect the system of yearly salaries for Party and government principals. By reforming the personnel system, the awareness of crisis on the part of the entire staff was evidently enhanced, the quality of medical services was significantly improved, and the advancement mechanism of the health cause was rendered more flexible. As a result, the development of the health cause in rural areas was pushed to a new stage.

Objective To explore the feasibility and safety of right ventricular septal pacing with active fixation electrodes.Methods This was a randomized and control clinical trial.Patients implanted with pacemaker were randomly divided into two groups.One group underwent the right ventrieular high septal pacing with the active fixation electrodes(RVS group),and the other group underwent the right ventricular apical pacing with the passive fixation electrodes(control group).The parameter was recorded in two groups in and after operation and compared accordingly.Results (1)There were no significant differences in the procedure time between two groups[averaged(59.6±3.2)and(60.2±3.7)minutes respectively].But the time of exposing X-ray was significant longer in RVS group.(2)There was no significant difference in acute implanting measurement,except perioperative and postoperative threshold 1 month in RVS group was higher than that in control group(P＜0.05 or＜0.01).After 3 months,there was no significant difference.(3)Impedance decreased significantly in 1 month and 3 months in RVS group[P＜0.01 or＜0.05).(4)There was no difference in R-wave sensing between two groups.(5)After 100%pacing,the mean QRS duration Was shorter in RVS group,but the difference was not significant.(6)Operations in two groups came off smoothly and there were no complications.Conclusion It is feasible and secure to pace from RVS with active fixation electrodes.

Objective:To investigate the application value of fusion indocyanine green fluorescence imagine (FIGFI) in laparoscopic common bile duct reexploration.Methods:The clinical data of 65 patients who underwent laparoscopic common bile duct reexploration at Henan Province People′s Hospital from Jan 2015 to Dec 2019 were collected. According to the operational manner, the patients were divided into the conventional laparoscopic group (control group, 35 patients) and the FIGFI laparoscopic group (study group, 30 patients). The intraoperative and postoperative data were analyzed.Results:Operation time, time to identify extrahepatic bile duct, intra operative blood loss, and conversion to open surgery were (195.7±9.2) min vs (147.2±9.3) min, (39.3±3.7) min vs (21.8±1.8) min, (203.2±34.6) ml vs (108.9±32.1) ml, 8 vs 1, between the control group and the study group, respectively ( P<0.05). Postoperative cholangitis, bile leakage, intra abdominal infection, pancreatitis, and hospital stay were 11vs 2, 9 vs 2, 8 vs 1, 8 vs 1, (13.5±0.9) d vs (7.4±0.9) d, between the control group and the study group, respectively ( P<0.05). There was no statistically difference in case of residual stones (5 vs 3) and gastrointestinal fistula (3 vs 1) between the control group and the study group, respectively ( P>0.05). Conclusions:FIGFI provides real-time visualization of the extrahepatic biliary tract while doing laparoscopic common bile duct reexploration.

The clinical data of 192 patients undergoing endoscopic thyroidectomy via thoracic and mammary approach from June 2010 to July 2015 were retrospectively analyzed.Tunnel bleeding occurred in 11 cases (hemorrhage group),which was associated with the incorrect level of puncture(P ＜ 0.01).The tunnel bleeding was stopped by percutaneous packet-suturing in all 11 cases.There were no significant differences in postoperative drainage [(65.4 ± 7.5) and (63.8 ± 7.1) ml],subcutaneous petechiae [1/11 and 1.1％ (2/181)],nursing costs[(135 ±20) and(132 ± 16) yuan],postoperative hospital stay[(4.5 ± 1.6) and (4.4 ± 1.3) d] and rehemorrhage [0/11 and 0.6％ (1/181)] between hemorrhage and nonhemorrhage groups.The results show that percutaneous packet-suturing is reliable and effective method for tunnel bleeding without additional postoperative complications.

Objective To investigate the therapeutic effect of laparoscopic radical resection of rectal carcinoma via natural orificespecimen extraction(NOSE). Methods Laparoscopic resection of rec-tal carcinoma was performed using NOSE technique in 35 cases of rectal cancer from October 2013 to 2015 July. Analysis of clinical data,postoperative exhaust time,the number of resected lymph node,and anastomotic leakage rate was conducted. Results All 35 cases underwent laparoscopic radical resection of rectal cancer with successful anus preservation. There were no preventive transverse colostomy. Among them,the success rate of laparoscopic radical resection via NOSE for rectal cancer was 85. 71%(30 /35). The operation duration ranged from 105 to 186 min(mean 129. 50 min). Anal exhaust time was 22 to 80 h(average 38. 13 h). Postoperative hospital stay lasted for 9 ~ 21 days(mean 10. 27 d). Anas-tomotic leakage occurred in 1 case and puncture infection in 2 cases. Conclusion Laparoscopic radical resec-tion of rectal carcinoma in middle and low rectal cancer is safe and reliable,which is worthy of being spread.

Objective To investigate the effect of continuous positive airway pressure therapy (CPAP) on heart rhythm and blood pressure variability in primary hypertensive patients with obstructive sleep apnea/hypopnea syndrome (OSAHS).Methods Ninety seven patients with OSAHS and primary hypertension were randomly divided into treatment group (n =49) and control group (n =48).Patients in control group receive antihypertensive medication only,while patients in treatment group received antihypertensive medication in combination with CPAP therapy for 4 weeks.The dynamic electrocardiogram (ESG) and ambulatory blood pressure for 24 h were measured before and after treatment in both groups.Results After CPAP treatment,the night index of standard deviation of the average NN intervals (SDANNniGHt) in treatment group was (89.0 ± 21.4) ms,while the day and night index of square root of the mean squared differences of successive NN intervals (rMSSDday and rMSSDnight) was (35.9 ± 17.2) ms and (45.7 ± 18.3) ms respectively.Compared with those before treatment,the index of SDANNnight was decreased and the indexes of rMSSDday and rMSSDnight were increased (P ＜ 0.01).Compared with control group,the SDANNnight was decreased,and the rMSSDday and rMSSDnight were increased (P ＜ 0.01,P ＜ 0.05).After CPAP treatment,the night index of low-frequency power (LFnight) in treatment group was (15.3 ± 5.7) ms,which was lower than that before treatment,and the night index of high-frequency power (HFnigh) was (16.3-± 8.1)ms,which was higher than that before treatment (P ＜ 0.01);the LFnight in treatment group was decreased and the HFnight was increased (P ＜ 0.01).After CPAP treatment,the day and night indexes of systolic blood pressure (SBPday and SBPnight) and the night indexes of diastolic blood pressure (DBPnigh) t in treatment group were (136.1 ± 13.4) mmHg,(128.7 ± 9.8) mmHg (1 mmHg =0.133 kPa),and(83.7 ±7.2)mmHg respectivley,which were all lower than those in control group (P ＜ 0.05 or P ＜ 0.01).The incidences of morning peak blood pressure and non-dipper hypertension in control group were significantly higher than those in treatment group (P ＜ 0.01).Conclusion CPAP therapy can effectively adjust the heart rate and blood pressure levels in patients with OSAHS and primary hypertension,especially in the night.

Objective To observe the effect of single kneeling position trunk intensive training on the balance of patients with stroke Pusher syndrome. Methods From January, 2014 to February, 2016, forty patients with stroke Pusher syndrome were randomly divided into observation group and control group equally. They all accepted routine rehabilitation, while the observation group added a trunk intensive training with one knee kneeled. They were assessed with Berg Balance Scale (BBS), Fugl-Meyer Assessment (FMA) of lower limb and Sheikh's Scale of Trunk Control before and after training. Results The scores of BBS, lower limb FMA and trunk control improved in both groups after eight weeks of treatment (t>1.756, P<0.05), and improved more in the observation group than in the control group (t>1.827, P<0.05). Conclusion Single kneeling trunk intensive training can effectively improve the balance in stroke patients with Pusher syndrome.

Objective Crossclamping of aorta causes a sudden increase in systemic vascular resistance. Spinal cord may suffer ischemic injury during aortic aneurysm surgery. This study was designed to evaluate the hemodynamic and and spinal cord protective effects of captopril during suprarenal aortic crossclamping in rabbits.Methods Twenty-four albino rabbits were randomly divided into three groups :sham operation group (A),control group (B) and captopril group (C). The descending aorta was crossclamped above the level of renal artery for 30 min and then declamped.In group C a bolus of captopril 2 mg?kg -1 was given intravenously 10 min before crossclamping followed by a 0.5mg?kg -1?min -1 infusion for 30 min. The same volume of normal saline was given in other 2 groups. The carotid artery pressure(BP 1) and femoral artery pressure(BP 2) were recorded before injection, 5, 20,30min after crossclamping and 5,60,180min after declamping. Spinal cord was examined at the level of T 10 and L 3 for morphological changes and MDA content 180 min after declamping.Results 1. BP 1 increased significantly after crossclamping in group B. In group C there was no significant change in BP 1 after crossclamping. In group C there was no significant change in BP 1 after crossclamping. In group B BP after declamping was significantly lower than that before crossclamping. In group C BP at 60 and 180 min after declamping was significantly higher than that at the same intervals in group B(P