1.Development of the U.S. Armed Forces Forward Surgical Team and some implications
Military Medical Sciences 2014;(7):560-562
The U.S.Armed Forces Forward Surgical Team ( FST) was first used in the Gulf War , while Operation Iraqi Freedom and Operation Enduring Freedom represented the largest military operations to date in which the FST has been utilized.The FST was an integral and major component of the Medical Brigade and provided support for echelon Ⅱmedical care.This paper describes the development of FST , investigates the roles, organization and training of FST and finally brings forward some enlightenment for health service development of Chinese PLA .
2.The Clinical efficacy in the treatment of early diabetic nephropathy from rosuvastatin combined with benaze-pril
Chinese Journal of Primary Medicine and Pharmacy 2014;(14):2130-2131,2132
Objective To explore the clinical efficacy in the treatment of early diabetic nephropathy from ro-suvastatin combined with benazepril .Methods 107 patients of early diabetic nephropathy in our hospital were retro-spectively analyzed .On the basis of the conventional treatment of diabetes ,the control group were treated with benaze-pril;while the observation group were treated with rosuvastatin combined with benazepril .Before and after treatment , the improvement of the related indicators were observed , such as blood glucose ,lipids and renal function .The clinical efficacy were comprehensively evaluated .Results The level of the fasting blood glucose and 2-hour postprandial blood glucose of the observation group were lower than those of the control group , the difference was significant ( t=9.785,9.525,all P<0.05);the blood lipid levels such as TC ,TG and LDL-C in the observation group were signifi-cantly lower than those of the control group .But the levels of HDL-c was significantly increased , the difference was significant(t=9.938,10.283,10.475,9.782,allP<0.05);the indicators of renal function such as UAER ,Scr and BUN were significantly lower than those of the control group , the difference was significant ( t =9.938,12.341, 11.265,9.982,all P<0.05);The total effective rate of the observation group was 94.55%,significantly higher than the 76.92%of the control group, the difference was statistically significant (χ2 =10.120,P<0.05).Conclusion The effect of rosuvastatin combined with benazepril for the treatment of early diabetic nephropathy is very significant which is worthy applying in clinical practice .
3.Curative effects of valsartan combined with Bailing capsule for the treatment of diabetic nephropathy
Chinese Journal of Primary Medicine and Pharmacy 2015;(6):886-888
Objective To discuss the curative effects and clinical safety of using valsartan combined with Bailing capsule to treat diabetic nephropathy ( DN) .Methods In our hospital ,90 patients with diabetic nephropathy were chosen and divided into the two groups ( 45 cases in each group ):the control group treated with 80mg/d of valsartan and the observation group given bailing capsules 9g/d on basis of the control group .Before and after 16 weeks treatment,two groups′24h urine trace albumin excretion rate (UAER),potassium,serum creatinine (SCr), urea nitrogen ( BUN) ,total cholesterol ( TC) ,triglycerides ( TG) ,fasting plasma glucose ( FPG) and blood rheology changes were recorded and compared .Results After treatment the observation group′s high shear viscosity ,low shear viscosity,whole blood reductive viscosity and blood plasma viscosity all significantly decreased ( t=6.236,10.659, 12.509 and 7.269,all P<0.05),and these indexes were significantly lower than those of the control group ( t=6.365,6.054,9.057 and 6.431,all P<0.05);Compared with before treatment 24h urine trace albumin excretion rate (UAER),potassium,serum creatinine (SCr),urea nitrogen (BUN),total cholesterol (TC),triglycerides (TG) and fasting plasma glucose ( FPG) of the two groups all decreased significantly ( t≥2.081,all P<0.05);After treat-ment,the observation groups′24h UAER,SCr,BUN,TC,TG and BUN all significantly decreased more than those of the control group (t≥2.211,all P<0.05);After treatment potassium,FPG,SBP and DBP of the two groups all had no significant difference (t≤1.976,all P>0.05);No adverse reactions such as heart ,liver and kidney happened in the two groups .Conclusion Using valsartan in joint with Bailing capsule for the treatment of diabetic nephropathy ( DN) has distinct curative effects and no obvious adverse reactions ,which is worthy of clinical promotion .
4.Simultaneous Determination of Coumarin Compounds in Yifu Pill by HPLC
Xiaoling LI ; Juanjuan DIAO ; Xinxia LI
China Pharmacy 2016;27(30):4299-4301
OBJECTIVE:To establish a method for the simultaneous determination of coumarin compounds in Yifu pill. METH-ODS:HPLC was performed on the column of Inertsil ODS-3 with mobile phase of acetonitrile-water(49∶51,V/V) at a flow rate was 1.0 ml/min,the detection wavelength was 320 nm,column temperature was 30 ℃,injection volume was 20 μl. RESULTS:The linear range was 5.16-206.4μg/ml for osthole (r=0.999 9),37.40-1 495.89μg/ml for isoimperatorin(r=0.999 9) and 9.95-318.34 μg/ml for columbianadin(r=0.999 9);RSDs of precision,stability and reproducibility tests were lower than 3.0%;recov-eries were 96.05%-103.19%(RSD=2.18%,n=9) for osthole,96.90%-103.09%(RSD=2.07%,n=9) for isoimperatorin, 95.50%-103.57%(RSD=2.15%,n=9)for columbianadin. CONCLUSIONS:The method is simple with good precision,stability and reproducibility,and can be used for the simultaneous determination of coumarin compounds in Yifu pill.
5.Application of MRI and Three-dimensional Ultrasound Diagnosis of Congenital Malformations in the Fetus
Qiang DIAO ; Ling ZHENG ; Lin LI
Chinese Medical Equipment Journal 2009;30(7):84-85
Obiective To discuss the diagnosis value, limitations and mutual complement of MRI and TDUI in the fetus. Methods, TDUI and MRI was performed in 24 cases pregnant women that suspected fetus congenital malformation by Ultrasound examination, the examination results were compared by MR1 and TDUI with the clinical results.Results The 9 cases congenital malformation of 24 cases pregnant women were found by MRI. The 9 cases were confirmed and 3 cases were more sufficient by MRI. The one case examined by MRI was normal other than Ultrasound examination. Conclusion MRI is superior to Ultrasound in diagnosing malformation of nervous system. The Ultrasound and the TDUI in particular is better in finding the surface malformation than MRI. In clinical application, MRI and Ultrasound must be connected to make up the limitation and have a definite diagnosis.
6.Theoretical discussion on promoting blood circulation and removing blood stasis therapy for restless leg syndrome
Yang ZHAO ; Qian DIAO ; Tao LI
International Journal of Traditional Chinese Medicine 2012;34(4):335-337
Peony and Licorice Decoction was effective in treating Restless leg syndrome(RLS) with the function of nourishing yin for softening liver,relaxing spasm and relieving pain.Clinical practice,ancient literature and Chinese medicine theory were comprehensively studied to conclude that blood stasis is the key cause of RLS.Promoting blood circulation and removing blood stasis was the crucial therapy for RLS.
7.Clinical features and etiology of neonatal anemia
Li WANG ; Jingjun DIAO ; Jun ZHANG
Chinese Pediatric Emergency Medicine 2013;20(5):501-503
Objective To investigate the clinical features,etiology and related clinical factors in neonatal anemia.Methods Two hundreds and sixty four infants admitted to the Neonatal Intensive Care Unit between January 2009 to March 2012 were retrospectively analysed with different levels,different age,different gestational age.Results Among 264 patients,the occupancy of blood loss anemia was 54.5 %.Mild and medium neonatal anemia were more than severe anemia (172 vs 92).Fetomaternal hemorrhage syndrome occurred commonly in severe anemia (16.3%,15/92).Early anemia was more than late anemia(182 vs 82).Hemorrhagic anemia in early anemia (64.3%,117/82)occurred mainly.Late anemia with infection mainly (67.1%,55/82).Fetomaternal hemorrhage syndrome were all early anemia and term to account for a higher proportion (94.4%,17/18);twin-to-twin transfusion syndrome occurred commonly among preterm term infants (96.7%,29/30).Conclusion Blood loss anemia was the main etiological factor resulting in neonatal anemia.The incidence of mild and medium neonatal anemia was quite high.Early anemia was more than late anemia.There might be some differences in the etiology between term and perterm infants.
8.Missions and tasks of research hospitals in the healthcare reform
Yanjun WANG ; Weikai LI ; Tianxi DIAO ;
Chinese Journal of Hospital Administration 2016;(1):12-15
Based on a study of the relationship between research hospitals and furthering of the healthcare reform,the authors hold that a key to the ongoing reform lies in building the hierarchical medical system,an objective in building and development of research hospitals as well.Furthering of the reform will highlight advantages of such hospitals,as they can play an important role in leading practice with theoretical innovation,translating frontier technology to clinical use,promoting the system to serve primary care,and upgrading quality effectiveness at general level.
9.Effects of acanthopanax senticosus injection on oxidative stress and apoptosis in the hepatic tissue after hepatic ischemia reperfusion in rats
Shumei DIAO ; Xiuhong CAI ; Jie LI
International Journal of Traditional Chinese Medicine 2015;(3):243-246
Objective To investigate the effects of Acanthopanax Senticosus Injection (ASI) on free radical metabolism and apoptosis in the hepatic tissue after hepatic ischemia-reperfusion in rats.Methods A total of 100 rats were randomly divided into 5 groups: a sham operation group, a model group, and groups of high-, medium- and low-dose ASI, 20 rats in each group. Seven days before modeling, the drugs had been given by intraperitoneal injection. The rats in the high-, medium- and low-dose groups were given ASI 40, 80 and 120 mg/kg, respectively, and the rats in the sham operation and model groups were given equivalent volume of normal saline. A rat model of hepatic ischemia reperfusion was induced by partial hepatic pedicle clamping followed by reperfusion. 2 h after reperfusion, the activities of SOD, GSH-Px, GST and the MDA level in the hepatic tissue were determined; the activities of ALT and AST in serum were also determined; the histopathological changes and hepatocyte apoptosis were observed using the HE staining and the TUNEL staining, respectively.Results In comparison with the model group, the activities of SOD (11.16 ± 2.31 U/mg, 10.63 ± 1.92 U/mgvs.7.34 ± 1.78 U/mg;P<0.01 orP<0.05), GSH-Px (15.48 ± 2..91 U/mg, 13.23 ± 1.87 U/mgvs. 10.35 ± 2.04 U/mg;P<0.01 orP<0.05), GST(1.76 ± 0.25 U/mg, 1.55 ± 0.22 U/mgvs.0.94 ± 0.18 U/mg;P<0.01 orP<0.05) in the hepatic tissue in the ASI high- and medium-dose groups were significantly increased; and the MDA level in the hepatic tissue significantly decreased (4.67 ± 1.24 nmol/mg, 4.93 ± 1.53 nmol/mgvs.10.29 ± 2.41 nmol/mg); the serum levels of ALT(671.82 ± 338.37 U/L, 803.91 ± 441.63 U/Lvs.1 416.22 ± 538.94 U/L;P<0.01 orP<0.05), AST(329.02 ± 161.88 U/L, 417.26 ± 182.37 U/Lvs.751.93 ± 262.75 U/L;P<0.01 or P<0.05) were significantly decreased; the histopathological changes and hepatocyte apoptosis in the ASI high-, medium - and low-dose groups were significantly reduced.Conclusions ASI could effectively attenuate oxidative stress in the, improve the histopathological changes, inhibit hepatocyte apoptosis, and protect against hepatic ischemia reperfusion injury in rats.
10.Theme clusters and evolutions of research on medical protection against nerve agents
Li SHENG ; Junhong WANG ; Tianxi DIAO
Military Medical Sciences 2015;(4):261-265
Objective To find the course of theme evolution for study of medical protection against nerve agents.Meth-ods A method of information visualization based on co-cited analysis was used.The research domain of medical protection against nerve agents was mapped using software VOSviewer.Results There were five research clusters including clinical research, oxime reactivators, detoxification and detection,and bioscavengers.Conclusion Theme evolution is described and research trends are predicted.