1.Effect of Renshen Jianxin Capsule on Insulin Resistance and Coagulation in Coronary Heart Disease
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(02):-
Objective To explore the effect of Renshen Jianxin Capsule on insulin resistance and coagulation in coronary heart disease. Methods Angina patients with Qi dificiency and blood stasis were randomly divided into Renshen Jianxin Capsule group (30 patients, treated by Renshen Jianxin Capsule and common western medicine) and metformin group (30 patients, treated by metformin and common western medicine). The changes of blood glucose, insulin sensitivity index (ISI), plasminogen activator inhibitor-1 (PAI-1) were observed after six weeks. Results Blood glucose and PAI-1 were decreased, ISI was improved significantly after treatment of Renshen Jianxin Capsule. There was no significant difference of PAI-1 in metformin group. Conclution Renshen Jianxin Capsule has similar effect with metformin in improving insulin resistance and better effect in improving coagulation.
2.Hematopoietic stem cell senescence
Chinese Pharmacological Bulletin 1986;0(06):-
Lifelong blood cell production is achieved by the capacity of hematopoietic stem cell(HSC) to differentiate and self-renew.A growing body of evidence suggest that DNA damage induced HSC senescence may be the principal mechanism of aging and HSC exhaustion in response to the stress exposure.Understanding the mechanisms of HSC senescence will help to find new therapeutics that can ameliorate HSC injury induced by chemo-and radiotherapy,elucidate the molecular mechanisms whereby leukemia/cancer stem cell arise and evade cancer therapy by escaping senescence,and identify the novel molecular targets for intervention.
3.THE INFLUENCES OF TRACE ELEMENT SELENIUMAND VITAMIN E ON SERUM LIPID PEROXIDE AND SERUM GPT IN RAT
Acta Nutrimenta Sinica 1956;0(01):-
The level of serum lipid peroxide in rat is increased as the age of rat increased gradually. When the animals were injected with sodium selenite (0.1mg/kg) and vitamin E (4mg/kg) for five weeks the serum lipid peroxide level was decreased, the combined use of sodium selenite and vitamin E could decrease the level of SGPT apparently.
4.Research progress on the clinical classification and treatment of metastatic Spinal Tumors
Chinese Journal of Clinical Oncology 2013;(14):869-872
The clinical classification of metastatic spinal tumors is based on the degree of malignancy, nervous system function, osteoclasia, and prognosis of patients. The application of this classification system is relatively simple. The assessment and evaluation of patients to estimate the period of survival can guide the individualized treatment of patients. Patients with clear surgical indications can choose to undergo a palliative operation, tumor resection, or total spondylectomy. Alternatively, other patients can opt to have mini-mally invasive surgery aside from the normal surgical approach. Stereotactic radiotherapy and intensity-modulated radiation therapy combined with the use of radiofrequency ablation, radiation, and other therapies can achieve local tumor control, relieve pain, and main-tain normal neurological function. Thus, the quality of life of the patient is improved. Percutaneous vertebroplasty, radiofrequency abla-tion, spinal endoscopy, and other modern forms of minimally invasive surgery will have more applications in the treatment of spinal metastatic tumors.
5.Taoist Thought Analysed and the Keeping in Good Health
Journal of Zhejiang Chinese Medical University 2014;(4):493-494,500
[Objective] Discuss the influence of Taoist thought of health, in order to establish Taoist theory support for Chinese medicine keeping in good health.[ Method]Through discussing the influence to health maintenance by the Taoist theory of laissez-faire, returning to nature, prevention of disease, venerating yin and softness, to summarize the importance of Taoist thought in health maintenance. [Result]Taoist thought plays an important role in Chinese medicine health maintenance, Taoist thought emphasizes nihility and innocence, returning to nature, and making life to return to original state, prevention treatment of disease, and also pays attention to the protection of yin, emphasizing the regulation of five internal organs. [Conclusion]Taoist thought is one of the important thoughts inheritance for thousands of years in China, the quietness of the laissez-faire Taoism, the thought of returning to nature, the prevention treatment of disease thought in tonifying physical and spiritual, the thought of venerating yin and softness, al have guiding significance for TCM in health maintenance.
6.Complicated Hospital Infection by Mucor in Liver Transplant Recipients:A Clinical Analysis
Aimin LI ; Li CAO ; Haiping ZHAO
Chinese Journal of Nosocomiology 2006;0(06):-
OBJECTIVE To investigate the incidence,symtoms and prognosis of hospital infection by Mucor after liver transplantation.METHODS The clinical data of all the patients with complicated hospital infection orthotopic by Mucor after orthotopic liver transplantation were analyzed restrospectively.RESULTS There were 9 cases with complicated hospital infection by Mucor from in 750 liver transplant recipients.Seven cases developed superficial incisional infection with delayed healing and rapid increased secretion on the surface of incisions.All of them recovered after antifungal therapy.Two cases had pulmonary Mucor infection combined with bacteria and died of multi-organ failure.CONCLUSIONS The incidence of hospital infection by Mucor in liver transplant recipients is about 1%.The most common symtoms are superficial incisional infection and the patients recover well.However,the cases with complicated pulmonary Mucor infection are difficult to treat and have a poor prognosis.
8.Coronary endothelial injury and jeopardy score of coronary artery lesion by angiography in angina patients
Lan HUANG ; Shiyong YU ; Aimin LI
Chinese Journal of Interventional Cardiology 1996;0(01):-
Objective To investigate the level of coronary endothelial injury and dysfunction, the jeopardy score of coronary artery lesion by angiography, and their correlations in patients with stable angina (SA) or unstable angina (UA). Methods The 20 patients with UA, 17 patients with SA and 18 patients excluding coronary heart disease (control) were studied. Blood samples were collected during percutaneous coronary intervention (PCI). To investigate the coronary endothelial injury and dysfunction, we measured the concentrations of nitric oxide (NO)? endothelin (ET) and the number of circulating endothelial cells (CEC) in coronary sinus blood. The jeopardy score for coronary artery lesion was evaluated according to the method by Califf. Results In angina patients, especially in UA patients, NO concentration in coronary sinus blood was lower, while ET concentration and CEC number were markedly higher than those in control group. The jeopardy scores showed no difference between UA and SA. The coronary endothelial injury and dysfunction showed a positive correlation with jeopardy scores. Conclusion The coronary endothelial injury and dysfunction is not only the initiation factor, but may play a key role in the progression of atherosclerosis and coronary heart disease. Coronary angiography combined with detection of coronary endothelial injury and dysfunction may better describe the lesion of coronary artery, and evaluate the prognosis of patients with coronary heart disease.
9.Supraorbital trans-eyebrow keyhole approach microsurgery for sellar tumors
Xiguang LIU ; Aimin LI ; Jun CHEN
Chinese Journal of Minimally Invasive Surgery 2005;0(11):-
Objective To discuss the technique of supraorbital transeyebrow keyhole approach microsurgery for sellar tumors. Methods A total of 33 cases of sellar tumors were treated in this hospital from July 2001 to June 2004. The resection of the tumor was achieved by way of a supraorbital eyebrow minicraniotomy through a 2.0 cm ? 3.0 cm keyhole approach. The surrounding cisterns of the sellar area were opened to expose underlying structures under microscope at proper angles. Results Of 26 cases of hypophysoma, a total resection was performed 19 cases, and a subtotal resection in 7 cases. Of 4 cases of craniopharyngioma, a total resection was performed 3 cases, and a subtotal resection, 1 case. One case of meningioma received a total resection, and 1 case of optic chiasm glioma underwent a partial resection. Postoperatively, transitory diabetes insipidus was observed in 5 cases, and grand mal epilepsy occurred in 1 case. There were no infection or bleeding after the operation. All the 33 cases were followed for 4~36 months (mean, 27 months). No recurrence of tumors was seen in the 24 cases of total resection. Postoperative radiotherapy was given in 7 cases of subtotal resection of hypophysoma, 1 case of craniopharyngioma, and 1 case of optic chiasm glioma, and no apparent enlargement of tumors was found. Conclusions Supraorbital transeyebrow keyhole approach microsurgery minimizes the unnecessary exposure of the brain and postoperative complications.
10.Identification of Chinese Cheqiancao by UV Spectrophotometry
Zhengqiu ZHANG ; Feng LI ; Aimin CAO
Chinese Traditional and Herbal Drugs 1994;0(12):-
17 Cheqiancao produced in China were identified by UV spectrophotometry. The differences of their UV spectra were listed.