OBJECTIVE: To evaluate the therapeutic effect of multi-plane operations in treating obstructive sleep apnea-hypopnea syndrome (OSAHS). METHOD: One hundred and fifteen patients with OSAHS diagnosed by polysomnography were treated with uvuplopalatopharyngoplasty. Eighteen of them were treated combining with nasal septal construction. Twenty six patients also received nasal septal construction and partial inferior turbinectomy. One patients also received Genioglossus advancement and partial resection of corpus linguae. Five patients also received partial resection of corpus linguae. Some patients with the nasal disease and/or the lingual hypertrophy; AHI > 40 and/or BMI > 30 are received tracheotomy before general anaesthesia. RESULT: According to the postoperative follow-up 43 patients, were cured, 46 patients were improved, 26 patients were invalid, the effective power was 77.4%. CONCLUSION The operative effective power were increased by multi-plane operations in OSAHS patients. The serious complication were prevented through tracheotomy before general anaesthesia in multi-plane operations of severe OSAHS.
Adult ; Aged ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Sleep Apnea, Obstructive ; surgery ; Treatment Outcome

OBJECTIVE: To investigate the effect of uvulopalatopharyngoplasty on change of serum erythropoietin levels in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) treatment. METHOD: Fifty-nine patients with OSAHS were treated through uvulopalatopharyngoplasty. Observing follow indexes of pre and postoperation: pharyngeal space, neck size. Pre and post-operative serum erythropoietin levels were detected. RESULT: Neck size, AHI, BMI, SaO2, distance between anterior pillars, distance between uvula and posterior wall, length of palatum, length of uvula and minimum sekar of pharynx oralis in preoperative patients were significant higher than those in postoperative patients (P<0.01). Neck size, BMI and minimum sekar of pharynx oralis in postoperative patients were significant higher than those in normal adults (P<0.01). There were no significant difference between postoperative patients and normal adults in distance between anterior pillars, distance between uvula and posterior wall, length of palatum, length of uvula (P>0.01). The level of EPO in preoperative patients were significant higher than that in postoperative patients (P<0.01). There was no significant difference between postoperative patients and normal adults in the level of EPO (P>0.01). CONCLUSION The level of EPO in OSAHS patients is higher than that in normal adults. It was correlative with AHI. The uvulopalatopharyngoplasty was efficacious in treatment of OSAHS. The levels of EPO were decreased through efficacious treatment.
Adult ; Aged ; Erythropoietin ; blood ; Female ; Humans ; Male ; Middle Aged ; Palate ; surgery ; Pharynx ; surgery ; Sleep Apnea, Obstructive ; blood ; surgery ; Uvula ; surgery ; Young Adult

Female ; Humans ; Middle Aged ; Propofol ; therapeutic use ; Pulmonary Embolism ; complications ; Ventricular Fibrillation ; drug therapy ; etiology