1.A Case of Pathologic Splenic Rupture as the Initial Manifestation of Acute Myeloid Leukemia M2.
Ji Sun HAN ; Sung Yong OH ; Sung Hyun KIM ; Hyuk Chan KWON ; Sook Hee HONG ; Jin Yeong HAN ; Ki Jae PARK ; Hyo Jin KIM
Yonsei Medical Journal 2010;51(1):138-140
A pathologic splenic rupture refers to a rupture without trauma. A splenic rupture as the initial manifestation of acute myeloid leukemia is extremely rare. In this study, we described a rare case of acute myeloid leukemia presenting principally as an acute abdomen due to a pathologic splenic rupture in a 35-year old male patient. We can assert that a pathologic splenic rupture in hematologic diseases is a potentially life-threatening complication, which necessitates immediate operative intervention. Any such patient complaining about left upper abdominal tenderness should be closely observed, and further diagnostic investigations (ultrasonograph of the abdomen, abdominal CT scan) should be initiated in order to rule out a splenic rupture. The oncologist should be aware of this rare initial presentation of acute myeloid leukemia (AML) M2, as the condition generally necessitates a prompt splenectomy.
Adult
;
Humans
;
Leukemia, Myeloid, Acute/*diagnosis/pathology/radiography
;
Male
;
Splenic Rupture/*diagnosis/pathology/radiography
;
Tomography, X-Ray Computed
2.An Unusual Radiologic Pattern of Cryptogenic Organizing Pneumonia: Diffuse Pulmonary Nodules in a Leukemia Patient.
Kai Hsiung KO ; Hsian He HSU ; Woei Yau KAO ; Ching Feng CHANG ; Ming Fang CHENG ; Guo Shu HUANG
Korean Journal of Radiology 2009;10(1):93-96
The radiological appearance of diffuse discrete pulmonary nodules associated with cryptogenic organizing pneumonia (COP) has been rarely described. We describe a case of COP in 49-year-old woman with acute myeloid leukemia who developed diffuse pulmonary nodules during the second course of induction chemotherapy. The clinical status of the patient and imaging findings suggested the presence of a pulmonary metastasis or infectious disease. A video-assisted thoracoscopic lung biopsy resulted in the unexpected diagnosis of COP as an isolated entity. Steroid therapy led to dramatic improvement of the clinical symptoms and the pulmonary lesions.
Cryptogenic Organizing Pneumonia/complications/*radiography
;
Diagnosis, Differential
;
Female
;
Humans
;
Leukemia, Myeloid, Acute/*complications/pathology
;
Lung/*radiography
;
Lung Neoplasms/radiography/secondary
;
Middle Aged
;
Multiple Pulmonary Nodules/complications/*radiography