No abstract available.
Leukemia* ; Precursor Cell Lymphoblastic Leukemia-Lymphoma* ; Precursor Cells, T-Lymphoid*

The statistical survey on 148 patients with herpes zoster was made. Among 148 patients, 78 were treated with sublesional injection of predinisolone-procaine for severe neuralgic pain. 1) The incidence of herpes zoster was increasing with age, reaching it's height at age of 41-60 group and declining thereafter (Fig. 1). 2) The ratio of severe neuralgic pain of herpes zoster to the total incidence of every age groups was increasing with age, being 23.5% in the youngest age group under 10 and 85.7% in the eldest age group between 71-80 (Table 1). 3) The ratio of zoster peetoralis to the total incidence was 70% and a case of generalized herpes zoster associated with lymphocytic leukemia was observed. 4) 78 cases of herpes zoster suffering from the severe neuralgic pain were treated with sublesional injection of predinisolone-proicaine. The effect was excellent, shortening it's eours and relieving pain. There were so complications of hematogenous dissemination, skin infection and atrophy after the injection, except one case of hematogenous dissemination in lymphocytic leukemia.
Atrophy ; Herpes Zoster* ; Humans ; Incidence ; Leukemia, Lymphoid ; Procaine* ; Skin

No abstract available.
Exons* ; Gene Rearrangement* ; Immunoglobulin Heavy Chains* ; Immunoglobulins* ; Leukemia, Lymphoid*

Adult ; China ; Humans ; Leukemia, Lymphoid ; diagnosis ; therapy ; Prognosis

Pyoderma gangrenosum is a neutrophilic dermatosis that may be associated acute leukemia. We report a case of pyoderma gangrenosum associated refractory acute biphenotypic leukemia wherein the malignant cells show a phenotype specific for myelogenous and lymphocytic leukemia. Histopathologic examination revealed moderate perivascular infiltrate consisting mainly of neutrophils and lymphocytes without involvement of leukemic cells in the skin lesions. Treatment with systemic steroid was followed by a characteristically rapid healing of the skin lesions.
Leukemia ; Leukemia, Biphenotypic, Acute* ; Leukemia, Lymphoid ; Lymphocytes ; Neutrophils ; Phenotype ; Pyoderma Gangrenosum* ; Pyoderma* ; Skin ; Skin Diseases

Granulocytic sarcoma(chloroma) is an uncommon and solid tumor composed of immature cells of the mycloid series usually seen during the course of myelogenous leukemia or myeloproliferative disorders. The common sites for the occurrence of granulocytic sarcoma are soft tissue, periosteum, bone, lymphoid tissue, skin, gastrointestinal tract and testis. But extradural presentation of the spine is very rare. We report two cases of extradural granulocytic sarcoma of the spine. Early recognition of the etiology of the paraplegia and the underlying systemic involvement with leukemia resulted in an excellent neurological and hematological outcome.
Gastrointestinal Tract ; Leukemia ; Leukemia, Myeloid ; Lymphoid Tissue ; Myeloproliferative Disorders ; Paraplegia ; Periosteum ; Sarcoma, Myeloid* ; Skin ; Spine* ; Testis

Pneumatosis intestinalis (PI) is an imaging phenomenon that represents air in the bowel wall. The cause of PI is variable, although specific etiologic factors remain unknown. It is an infrequent complication in leukemia patients and is associated with several medical and surgical conditions. PI often represents a benign condition, but it can also require surgery. Therefore, the assessment of PI with or without complications can be difficult. Herein, we report on an unusual case of a 63 year-old woman with refractory acute precursor B-cell lymphoblastic leukemia-lymphoma who presented with PI resulting from the leukemic process, and finally expired due to sepsis.
Female ; Humans ; Leukemia ; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma ; Precursor Cells, B-Lymphoid ; Sepsis

Humans ; Child ; Myeloid-Lymphoid Leukemia Protein/genetics* ; Precursor Cell Lymphoblastic Leukemia-Lymphoma ; Ubiquitin Thiolesterase

Humans ; Leukemia, Myeloid, Acute/genetics* ; Myeloid-Lymphoid Leukemia Protein/genetics* ; Oncogene Proteins, Fusion/genetics* ; Translocation, Genetic

Therapy-related myeloid neoplasms have been well characterized. However, precursor B-cell acute lymphoblastic leukemia in patients with prior malignancies is uncommon, and the effect of prior cytotoxic therapy on development of precursor B-cell acute lymphoblastic leukemia is controversial. Therapy-related precursor B-cell acute lymphoblastic leukemia has been reported occasionally. However, cytotoxic therapy-related precursor B-cell acute lymphoblastic leukemia has been reported in Korea only rarely. We herein describe two cases of therapy-related precursor B-cell acute lymphoblastic leukemia.
Humans ; Korea ; Precursor Cell Lymphoblastic Leukemia-Lymphoma ; Precursor Cells, B-Lymphoid