1.Bilateral Paramedian Thalamic Infarction due to Occlusion of Artery of Percheron.
Sun Woo PARK ; Sook Keun SONG ; Sa Yoon KANG ; Ji Hoon KANG ; Jung Seok LEE
Journal of the Korean Neurological Association 2013;31(3):189-191
The thalamic vascular supply is categorized into the anterior, paramedian, inferolateral, and posterior territories. The artery of Percheron (AOP), a solitary trunk that is an uncommon anatomic variant, provides bilateral arterial supply to the paramedian thalami and the rostral midbrain. Occlusion of this artery results in bilateral thalamic and mesencephalic infarctions. The case described herein is of a patient with AOP who presented with the sudden onset of lethargy.
Arteries
;
Humans
;
Infarction
;
Lethargy
;
Mesencephalon
;
Thalamus
2.Bilateral Paramedian Thalamic Infarction due to Occlusion of Artery of Percheron.
Sun Woo PARK ; Sook Keun SONG ; Sa Yoon KANG ; Ji Hoon KANG ; Jung Seok LEE
Journal of the Korean Neurological Association 2013;31(3):189-191
The thalamic vascular supply is categorized into the anterior, paramedian, inferolateral, and posterior territories. The artery of Percheron (AOP), a solitary trunk that is an uncommon anatomic variant, provides bilateral arterial supply to the paramedian thalami and the rostral midbrain. Occlusion of this artery results in bilateral thalamic and mesencephalic infarctions. The case described herein is of a patient with AOP who presented with the sudden onset of lethargy.
Arteries
;
Humans
;
Infarction
;
Lethargy
;
Mesencephalon
;
Thalamus
3.A Case of Adrenocortical Insufficiency(hypoaldosteronism).
So Kyung PARK ; Seung Ju LEE ; Keun LEE ; Duk Hee KIM
Journal of the Korean Pediatric Society 1980;23(9):741-747
A case of isolated hypoaldosteronism 5 month old male infant was presented. He was admitted to the pediatric ward with the chief complants of frequent vomiting, dehydration, lethargy and failure to thrive. The diagnosis was established by salt-losing manifestation, laboratory fiding and good response after salt-retaining steroid therapy. A brief review of related literatures were also presented.
Dehydration
;
Diagnosis
;
Failure to Thrive
;
Humans
;
Hypoaldosteronism
;
Infant
;
Lethargy
;
Male
;
Vomiting
4.Desmoplastic Cerebral Astrocytoma of Infancy.
Gyeong Bum KIM ; Jae Taeck HUH ; Young Jin SONG ; Hea Kyoung HUH ; Seo Hee RHA ; Jin Sook JEONG ; Sun Seob CHOI
Journal of Korean Neurosurgical Society 1998;27(12):1716-1722
Desmoplastic cerebral astrocytoma of infancy is a massive cystic tumor, typically occurring in the cerebral hemisphere and a rare intracranial tumor that arises in subjects usually below the age of 18 months and shows a favorable prognosis. A 5.5-month-old boy was presented with a rapidly increasing head circumference and lethargy. A computerized tomography scan revealed a large, multicystic, partially enhancing right parieto-occipital mass with hydrocephalus. This patient was treated with a surgery and a firm plaque-like tumor along withmulticystic component was gross totally removed. The tumor mass was firmly attached to the dura and extended in fingerlike projections onto the cortical surface. The infant underwent no further therapy and has developed normally during 6 months after surgery. Desmoplastic cerebral astrocytoma of infancy is a rare intracranial tumor but recognition of this tumor should be appreciated because, despite its massive size and rapidly growing characterstics, this tumor often has a relatively benign clinical course.
Astrocytoma*
;
Cerebrum
;
Head
;
Humans
;
Hydrocephalus
;
Infant
;
Lethargy
;
Male
;
Prognosis
5.Symptomatic Hypermagnesemia in Normal Kidney Function with a Colonic Cleansing Agent.
Taehong KIM ; Tae Hyung KIM ; Won Hyuk LEE ; Yoo Jin LEE ; Sihyung PARK ; Bong Soo PARK ; Yang Wook KIM
Korean Journal of Medicine 2016;91(3):306-310
Most reported cases of hypermagnesemia are related to laxative abuse and impaired renal function, while hypermagnesemia is uncommon without iatrogenic magnesium administration and decreased renal function. Magnesium-containing bowel-cleansing agents are widely used before colonoscopy, usually without complications. However, we experienced a case of symptomatic hypermagnesemia with normal renal function after using a bowel-cleansing agent. A 74-year-old man with normal renal function complained of lethargy and motor weakness after taking a bowel-cleansing agent containing 14 grams of magnesium before a colonoscopy for hematochezia. His magnesium level was 12 mg/dL. Fluid stasis in the gut due to colonic obstruction might have caused the hypermagnesemia. He was treated successfully with a bowel enema and intravenous calcium. We should be cautious when prescribing drugs for colonoscopy if colonic obstruction is suspected.
Aged
;
Calcium
;
Cathartics
;
Colon*
;
Colonoscopy
;
Detergents*
;
Enema
;
Gastrointestinal Hemorrhage
;
Humans
;
Kidney*
;
Lethargy
;
Magnesium
6.Isolation and molecular identification of Vibrio harveyi from the look down fish (Selene vomer).
Jin Woo JUN ; Young Ran LEE ; Sib Sankar GIRI ; Hyoun Joong KIM ; Sae Kil YUN ; Cheng CHI ; Sang Guen KIM ; Jeong Rack KOH ; Ji Yun JUNG ; Byeong Chun LEE ; Se Chang PARK
Korean Journal of Veterinary Research 2016;56(2):125-127
Gradual mortality of look down fish (Selene vomer) was observed in a private aquarium in Seoul, showing abnormal swimming behavior and lethargy. A bacterial pathogen from kidney was cultured, identified, and confirmed as Vibrio harveyi using Vitek System 2 and 16S rRNA gene sequencing. A predominant bacterial strain, SNUVh-LW2 was proved to be most closely related to isolates from China by phylogenetic analysis with minimum evolution method. Also, tetracycline was considered as the most sensitive antibiotic agent via antibiotic usceptibility test. The group of fish was treated according to the diagnostic result and no more mortality was observed.
China
;
Genes, rRNA
;
Kidney
;
Lethargy
;
Methods
;
Mortality
;
Seoul
;
Swimming
;
Tetracycline
;
Vibrio*
7.An Unusual Variant of Anlage Tumor of Pineal Region in an Infant.
Raghvendra RAMDASI ; Kanchan KOTHARI ; Naina GOEL ; Amit MAHORE
Brain Tumor Research and Treatment 2015;3(1):52-55
A 9-month-old male child was brought with complaints of increasing head size for 2 months, increasing lethargy and vomiting for the last 2 days. Radiology revealed a heterogeneously enhancing, globular lesion in the pineal region with hydrocephalus. Near total excision of the tumor was carried out. The histopathological examination of the lesion showed heterogenous elements in the form of mature neuroepithelial and ectomesenchymal tissue. The pathology and radiology of this unusual lesion is discussed with relevant review of literature.
Cartilage
;
Child
;
Head
;
Humans
;
Hydrocephalus
;
Infant*
;
Lethargy
;
Male
;
Melanins
;
Pathology
;
Pinealoma
;
Vomiting
8.Neurologic Complications Associated with Respiratory Syncytial Virus Infection in Childhood.
So Won YOON ; Hyoung Jin KIM ; Myung Kul YUM ; In Joon SEOL
Journal of the Korean Child Neurology Society 2008;16(2):206-212
PURPOSE: Respiratory syncytial virus(RSV) mainly brings about respiratory complication, but it can also be related to neurologic complication. We have studied clinical aspect and incidence of neurologic complication associated with RSV infection. METHODS: We reviewed the medical records of 732 children with RSV infection who were admitted to the department of pediatrics, Hanyang University hospital from November 2002 to June 2007 and studied on existence of neurologic complication, age, sex, clinical symptom, characteristics of seizure, and laboratory findings. RESULTS: Neurologic complications were occurred in 52 patients(7.1%) among 732 patients. Among them, 14 patients(1.9%) had seizure and 38 patients(5.2%) had alteration of mental status such as drowsy, lethargy. Age distribution of patients with neurologic complication was from 1 month to 5 years(mean 16.4 months). There were 30 boys and 22 girls. Among 14 patients who had seizure, 2 patients had convulsion disorder, 3 patients had febrile convulsion, and 9 patients had no seizure before. Their age distribution was from 1 months to 4 years(mean 18.4 months) and there were 8 boys and 6 girls. All of 14 patients showed generalized tonic clonic seizure and durations were from 30sec to 15 min(mean 4.4 min). All of the investigations were normal. None of 52 patients had recurrence and neurologic sequelae. CONCLUSION: It is important to know that RSV can cause CNS complications because we know how many patients infected by RSV. RSV-related seizure can be considered as benign seizure which does not need any long-term antiepileptic medication.
Age Distribution
;
Child
;
Humans
;
Incidence
;
Lethargy
;
Medical Records
;
Pediatrics
;
Recurrence
;
Respiratory Syncytial Viruses
;
Seizures
;
Seizures, Febrile
9.A Clinical Study on Sepsis in Children: esp. about buffy coat smear.
Nam Keun CHO ; Haeng Mi KIM ; Sang Bum LEE ; Ja Hoon KOO ; Sung Yong SEOL
Journal of the Korean Pediatric Society 1980;23(5):376-383
A clinical and laboratory study was conducted on 58 children who had been admitted to out pediatric department from February to September 1979, under the clinical diagnosis of septicemia. Following results were obtained: 1. Boys were affected more frequently than girls(1.3:1), and highest incidence was noticed in newborn period, comprising 50% of the total cases. 2. The common clinical manifestations, in order of frequency, were fever, lethargy, jandice, poor sucking and abdominal distension, and hyperbilirubionemia was the most common assocaited disease, followed by anemia and leukemia. 3. Clinical course revealed death in 6 patients(10.3%), discharge against advice in 7cases(21.1%) and complete recovery in the remaining 45 cases(77.6%). 4. Peripheral blood count showed leukocytosie in 40%, leukopenia in 12.1% and thrombocytopenia was seen in 45% of cases. 5. Gram staining of buffy coat smear showed bacteria in 34.5% and especially high ratio was noticed in newborn infants(48.3%). 6. Positive blood culture was seen in 39.7% with highest ratio of 45% in newborn infants. In positive blood culture group, toxic granules were noted in 32.8%, shift to left in 25.9%, hrombocytopenia in 18.9% and positive buffy coat smear in 15.5%. In summary, thrombocytopenia, toxic granules, shift to left were quite helpful in early diagnosis of sepsis. In addition to diagnostic value, examination of buffy coat smear could aid physician to select appropriate antibiotic regimen especially in sepsis of newborn period.
Anemia
;
Bacteria
;
Child*
;
Diagnosis
;
Early Diagnosis
;
Fever
;
Humans
;
Incidence
;
Infant, Newborn
;
Lethargy
;
Leukemia
;
Leukopenia
;
Sepsis*
;
Thrombocytopenia
10.A Preliminary Study for the Rating of Pharmacological Effect with Aberrant Behavior Checklist in Children with Autistic Disorder.
Duk Soo MOON ; Un Sun CHUNG ; Sung Hoon JUNG ; Ah Rang CHO ; Geon Ho BAHN
Journal of the Korean Academy of Child and Adolescent Psychiatry 2013;24(3):164-169
OBJECTIVES: We assessed the availability of Aberrant Behavior Checklist (ABC) for the evaluation of the pharmacological effect in autistic disorder. METHODS: A retrospective review of the medical records of 27 children with autistic disorder, who visited the department of child and adolescent psychiatry of Kyungpook National University Hospital, from October 2011 to February 2013, was conducted. After treatment with risperidone, changes in the severity and improvement of symptoms were measured using ABC at the baseline, 2nd visit and 3rd visit, respectively. RESULTS: The mean daily dose of risperidone increased from 0.66+/-0.27mg (baseline, initial dose) to 1.02+/-0.50mg, 2nd visit, and 1.19+/-0.50mg, 3rd visit. According to ABC, irritability, lethargy, hyperactivity, and inappropriate speech subscale scores decreased significantly from the baseline to 2nd visit. Irritability and Hyperactivity subscale scores decreased significantly from the 2nd to 3rd visit. All subscales and total scores of ABC decreased significantly from the baseline to 3rd visit. CONCLUSION: The results of this study suggest that ABC can be used as an efficient tool to measure the symptoms of autistic disorder and to evaluate the medication effect on continuous treatment.
Adolescent
;
Adolescent Psychiatry
;
Autistic Disorder*
;
Checklist*
;
Child*
;
Humans
;
Lethargy
;
Medical Records
;
Retrospective Studies
;
Risperidone