1.Early treatment of sylvian fissure contusion of brain caused by traffic accident
Lesheng CAO ; Yulin NIE ; Zhengming JIANG ; Yulu MIAO ; Wan ZHAO
Chinese Journal of Trauma 1990;0(04):-
Objective To analyze the relationship of pathogenesis and early management with prognosis of sylvian fissure contusion of brain caused by traffic accident. Methods A review was done on 36 cases with sylvian fissure contusion of brain caused by traffic accident, in which early improvement of respiration and management of combined injuries were performed according to injury severity and pathogenesis. Standard big bone flap craniotomy was done in 31 cases including bilateral craniotomy in 13. Of nine cases treated conservatively, four cases turned to operation due to aggravation. Results Of all, 18 cases recovery better but death occurred in eight, vegetative state in two, bad disability in two and moderate disability in six. Conclusions Early synthetic treatment, prompt decompression with standard big bone flap, paying attention to sylvian fissure contusion in the midline area, dynamic observation of injury and effective treatment can improve prognosis and reduce mortality rate.
2.Inactivation mechanism of microorganisms by the synergy of silver and light irradiation, and the application in household electrical appliances.
Jinshan HE ; Yoshifumi MORIYA ; Takemi OKETA ; Shigeru SASABE ; Hirofumi NISHIDA ; Lesheng CHEN ; Shenmin ZHU ; Di ZHANG ; Hideki OMORI ; Guangyi CAO
Chinese Journal of Biotechnology 2008;24(6):1091-1097
The inactivation efficiencies of microorganisms were found to be enhanced by using silver solution together with ultraviolet light (UV-A, 395 nm) irradiation. The inactivation efficiencies were improved remarkably especially in eukaryotic microorganism. To make clear the inactivation mechanism of microorganisms by the combination effect of silver and ultraviolet light irradiation, the resultant solution was characterized by ESR (Electron spin resonance, ESR). Scanning electron microscopy (SEM) and the methnd for measuring enzyme activity of mitochondria for eukarvotic cells were used to conjecture the mechanism, by analysis of the morphological and physiologic changes in eukaryotic cells. It is proposed that silver oxide (Ag20) can be activated by ultraviolet light irradiation and react with water molecules to produce hydroxyl radical (.OH). Hydroxyl radical could damage cell wall of eukaryotic microorganisms, and inactivate the enzyme activity of mitochondria of eukaryotic microorganism cells. Accordingly, eukaryotic microorganism cells would die. In the experiment, Staphylococcus aureus was employed as the representative of prokaryotic microorganisms, and Candida albicans and Trichophyton mentagrophytes as the representative of eukaryotic microorganisms, respectively. Moreover, the results of the technology applied to washing machine were presented and discussed.
Anti-Infective Agents
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pharmacology
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Candida albicans
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drug effects
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radiation effects
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Disinfection
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methods
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Household Articles
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Silver
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pharmacology
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Staphylococcus aureus
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drug effects
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radiation effects
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Trichophyton
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drug effects
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radiation effects
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Ultraviolet Rays