No abstract available.
Leptin* ; Metabolism*

No abstract available.
Adolescent ; Humans ; Leptin* ; Puberty*

No Abstract available.
Asthma* ; Child* ; Humans ; Leptin*

No abstract available.
Bariatric Surgery* ; Ghrelin* ; Leptin*

No abstract available.
Colorectal Neoplasms* ; Leptin*

No Abstract Available.
Body Weight* ; Eating* ; Leptin*

Perimenopausal period is a period with high incidence of female depression, which shows the symptoms of depressed mood and disturbed mind. The pathogenesis of the disease is not clear and it is urgent to search for efficient treatment. Leptin is a hormone secreted by fat cells and plays a role in both metabolism and neuroprotection. In recent years, leptin has been reported to ameliorate perimenopausal depression, and leptin is closely related to estrogen synthesis and secretion. Therefore, leptin may be used as a potential molecular target for the treatment of perimenopausal depression. In this paper, the research on the relationship between leptin and perimenopausal depression is reviewed.
Depression ; Leptin ; Estrogens

Leptin is a versatile 16 kDa peptide hormone, with tertiary structure resembling that of members of the long-chain helical cytokine family. It is mainly produced by adipocytes in proportion to fat size stores, and was originally thought to act only as a satiety factor. However, the ubiquitous distribution of leptin receptors in almost all tissues underlies the pleiotropism of leptin. This review will focus on the link between leptin, a cytokine that is elevated in obese individuals, and cancer development through clarifying the intracellular signaling pathways of leptin. First, I discuss the biological functions of leptin and its signaling pathways. Then, I summarize the effects of leptin on different cancer types in experimental cellular and animal models. Next, I analyze the relationship between obesity and the presence of cancer or cancer risk in patients. Finally, leptin as a target for cancer treatment in the future and prevention will be discussed.
Adipocytes ; Carcinogenesis ; Humans ; Leptin ; Models, Animal ; Obesity ; Receptors, Leptin

No abstract available.
Eating* ; Glucose* ; Leptin* ; Metabolism* ; Resistin*

PURPOSE: The aims of this study is to analysis the effects of obesity management programs for children and to measure the differences in the effects by type and dependent variables in order to analyze the structures of the programs. METHODS: Sixty-one peer-reviewed journals including child obesity and intervention studies published between 2000 and 2010 were included for meta-analysis. Effect size and statistics of homogeneity were by STAT 10.0. RESULTS: A total of 61 studies were used in the analysis, and the effect size of the independent studies was determined to be -0.23 (95% CI, -0.32 ~ -0.15). Serum Leptin and Insulin were the big effect size among the studies that used dependent variables. The theses used in the research did not display publishing bias. CONCLUSION: Obesity management programs that have been confirmed to be effective need to be developed into regional protocols. A continuous control of obese children and research for effective intervention program are in need.
Child* ; Humans ; Insulin ; Clinical Trial ; Leptin ; Obesity*