1. Chemical composition of Rosmarinus officinalis essential oil and antioxidant action against gastric damage induced by absolute ethanol in the rat
Christiane TAKAYAMA ; Ana Cristina Alves DE ALMEIDA ; Alba Regina Monteiro SOUZA-BRITO ; Felipe Meira DE-FARIA ; Ricardo José DUNDER ; Luis Paulo MANZO ; Eduardo Augusto Rabelo SOCCA ; Alba Regina Monteiro SOUZA-BRITO ; Leonia Maria BATISTA ; Marcos José SALVADOR ; Anderson LUIZ-FERREIRA
Asian Pacific Journal of Tropical Biomedicine 2016;6(8):677-681
Objective To evaluate the antioxidant activity of the essential oil obtained from Rosmarinus officinalis (R. officinalis) in ethanol-induced gastric ulcer model in vivo. Methods The antioxidant properties of the essential oil obtained from R. officinalis were evaluated against gastric injury induced by absolute ethanol. Gastric tissues were prepared to enzymatic assays. The levels of glutathione, lipid peroxides, and the activities of glutathione peroxidase, superoxide dismutase and myeloperoxidase were measured. Results Ethanol produced severe hemorrhagic lesions in the stomach with ulcerative lesion of (140.2 ± 37.2) mm
Result Analysis
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