1."The one" annoying patient.
Leonard L L YEO ; Andre T S TAY
Annals of the Academy of Medicine, Singapore 2006;35(2):123-126
Adult
;
Humans
;
Male
;
Prognosis
;
Schizophrenia
;
diagnosis
;
therapy
;
Schizophrenic Psychology
4.How an Occluded Artery Recanalizes during Acute Stroke Thrombolysis.
Vijay K SHARMA ; Leonard L L YEO ; Hock L TEOH
Journal of Cardiovascular Ultrasound 2015;23(1):56-57
No abstract available.
Arteries*
;
Middle Cerebral Artery
;
Stroke*
5.Prophylactic Dual Catheter Technique to Prevent Side Branch Snowplowing Complications during Angioplasty and Stenting.
Leonard LL YEO ; W M WU ; Y L CHEN ; C H YEH ; H F WONG
Journal of Cerebrovascular and Endovascular Neurosurgery 2017;19(1):12-18
OBJECTIVE: Angioplasty and Stenting of intracranial atherosclerotic lesions have a higher complication rate and a large proportion of this is attributable to side branch arterial occlusion from forceful displacement of the atheroma into the ostia or snowplowing effect. This can result in severe disabilities when it result in small infarcts involving eloquent areas in the posterior circulation or the motor tracts. MATERIALS AND METHODS: We present a series of 6 cases utilizing a new dual catheter technique for maintaining the patency of at-risk vessels during angioplasty and stenting. There are several methods previously described to help reduce the incidence of stroke but because they do not have a physical presence in the ostia to protect it, they are unable to guarantee the patency of the vessel. RESULTS: All 6 patients underwent angioplasty and stenting with the technique. The patients were assessed for complications with post-procedure magnetic resonance imaging and no complications were found. CONCLUSION: In this preliminary series, the dual catheter technique appears to safe and effective in preventing occlusion of the adjacent branch arteries. This technique may facilitate the use of the Wingspan stent in the treatment of intracranial atherosclerotic stenotic segments by reducing the risk of peri-procedural stroke.
Angioplasty*
;
Arteries
;
Catheters*
;
Humans
;
Incidence
;
Magnetic Resonance Imaging
;
Plaque, Atherosclerotic
;
Stents*
;
Stroke
6.Health Economic Impact of First Pass Success: An Asia-Pacific Cost Analysis of the ARISE II Study
Leonard YEO ; Osama O. ZAIDAT ; Jeffrey L. SAVER ; Heinrich P. MATTLE ; Stephanie Hsiao Yu LEE ; Emilie KOTTENMEIER ; Heather L. CAMERON ; Rana A. QADEER ; Tommy ANDERSSON
Journal of Stroke 2021;23(1):139-143
7.Long-term outcomes of ischaemic stroke patients with diabetes in a multi-ethnic cohort in Singapore.
Ei Zune THE ; Mei Yen NG ; Geelyn JL NG ; Bernadette GC ER ; Amy ML QUEK ; Prakash PALIWAL ; Leonard L YEO ; Bernard CHAN ; Vijay K SHARMA ; Hock Luen TEOH ; Eric YH KHOO ; Raymond CS SEET
Annals of the Academy of Medicine, Singapore 2021;50(1):16-25
INTRODUCTION:
Diabetes increases the risk of ischaemic stroke especially among Asians. This study aims to investigate contemporaneous long-term cardiovascular outcomes of ischaemic stroke patients with diabetes in a multi-ethnic Asian cohort.
METHODS:
Consecutive patients with ischaemic stroke were recruited from the National University Hospital, Singapore. Data on age, gender, ethnicity, risk factors (including diabetes status and body mass index [BMI]), stroke severity and mechanisms were collected. These patients were followed up until the day of the first cardiovascular event or July 2016, whichever was earlier. The primary endpoint was the time from enrolment to the first occurrence of a composite of cerebrovascular and coronary artery events.
RESULTS:
Between July 2011 and December 2013, 720 patients (mean age 60.6 years, 71% men, 43% with diabetes, median National Institute Health Stroke Severity scale 2) were enrolled and followed up. A total of 175 cardiovascular events occurred during a median follow-up of 3.25 years (6.90 events per 1,000 person-month), comprising 133 cerebrovascular and 42 coronary artery events. The adjusted hazard ratio of diabetes was 1.50 (95% CI 1.08-2.10). In a multivariable Cox proportional hazards model, Malay and Indian ethnicities, BMI <23kg/m2 and a prior diagnosis of diabetes were identified as independent predictors of recurrent cardiovascular events.
CONCLUSION
Our study provides quantitative data on the event rates of ischaemic stroke patients with diabetes. These findings provide insights on stroke predictors in a multi-ethnic Asian population, which may have implications in the design of future interventional studies.