1.Prefabricated skin tube of autologous tissue in the repair and reconstruction of urethra
Chinese Journal of Tissue Engineering Research 2009;13(28):5571-5574
OBJECTWE: To explore the effect of prefabricated skin tube of autologous tissue on treating congential hypospadias, long-segment urethral stricture, and severe complications following hypospadias surgery. METHODS: Twenty-four male patients, who underwent treatment with prefabricated skin tube which was sutured from autologous scrotum, the penis foreskin, and testes sheath, and embedded in situ, for urethral stricture, hypospadias, severe complications following hypospadias, were selected and analyzed retrospectively. The age range was 5 to 56 years old, and the average was 14 years old. Of the 24 cases, 11 cases underwent urethroplasty for secondary hypospadias repair using skin tubes preset in the prepuce, nine cases of post-hypospadias complications were treated with prefabricated sheath canal, and four cases received prefabricated scrotal skin tube to treat long-segment stricture of the anterior urethral. The application of autologous tissue-prefabricated skin tube in the treatment of urethral stricture, hypospadias, and postoperative complications of hypospadias was observed.RESULTS: All the cases received a follow-up of 6 to 12 months. Of the 11 cases receiving urethroplasty for secondary hypospadias repair using skin tubes preset in the prepuce, one case was complicated with urethrostenosis, one was with anastomosis stricture and they were both cured following urethra dilatation. Of the nine cases of post-hypospadias complications treated with prefabricated sheath canal, there were 2 cases of bulky of penis. Of the four cases receiving prefabricated scrotal skin tube to treat long-segment stricture of the anterior urethral, one case was found complicated with anastomosis stricture. No other complications such as urethrocutaneous fistula and urethral diverticulum were found, and the flow rate was at or near the level of the peers.CONCLUSION: Leaming from the experience of plastic surgeries, skin tubes prefabricated with autologous tissues, such as penis foreskin, testis sheath, scrotal skin near the urethral, is beneficial to the recover of urethral function through urethroplasty for secondary hypospadias repair or repair of urethral defect. The incidence of urethrostenosis and anastomosis stricture is less by this way. It is a better surgical method to repair and reconstruct the urethra.
2.Application values of flexible ureteroscope in treatment of retained kidney calculi after percutaneous nephrolithotomy
Leizhen CHEN ; Haifeng XU ; Tao FENG ; Shubo CHEN ; Junli WEI ; Donghui JI
Chinese Journal of Postgraduates of Medicine 2015;38(3):160-163
Objective To explore the effect of flexible ureteroscope in treatment of retained kidney calculi after percutaneous nephrolithotomy.Methods Thirty-six patients with retained kidney calculi after percutaneous nephrolithotomy who were treated with flexible ureteroscope were selected,and clinical data of the patients were retrospectively analyzed.Results In the 36 patients,26 patients were through the percutaneous nephroscope channel,and 10 patients were through the ureter channel.Except for 1 patient who stopped the operation because of poor visibility caused by active bleeding in percutaneous nephroscope channel lithotripsy 7 d after percutaneous nephrolithotomy,other patients did not appear severe complication.All the patients were rechecked plain abdominal radiograph the second,seventh and fourteenth day after this operation,and the eradication rates of calculi were 13.9% (5/36),69.4% (25/36) and 94.4% (34/36).Two patients still had less than 0.4 cm retained calculi in lower renal calices and were followed up.Conclusions The retained kidney calculi after percutaneous nephrolithotomy can be effectually treated by flexible ureteroscope,and it can avoid secondary percutaneous nephrolithotomy or multichannel percutaneous nephrolithotomy,and inprove the eradication rate of complex kidney calculi by percutaneous nephrolithotomy.The method is economical,safe,simple and with little injury,and it is the effective supplement protocol of percutaneous nephrolithotomy.