Female patient, 29 age, married, lives in Ha Long. Admitted of hospital 16/03/2001. Reason for admitted hospital: prolonged fever symtoms: splenomegaly, hepatomegaly, enlargement of the lymph glands, anemia, purpura. Investigation: thrombocytopenia, hypohemoglobin, hyperglobulin, HIV positive. Hypermacrophages were indentidied by microsscopy in the bone marrow smear: parasites in macrophages look like Amastigote of Leishmania parasites in the atlas (the morphology of human blood cells- abbott laboratories). Born marrow cultured in NNN medium: identidied promastigote. Diagnosis: visceral Leishmaniaxsis. It was confirmed by Karolinska hospital of Sweden, China, Singapore, Australia. This is first case indentified in Vietnam
Leishmaniasis, Visceral ; Leishmania donovani

A female patient 29 years old, married, lived in Halong was admitted to hospital in 16/03/2001. Reason for admitting hospital: prolonged fever. Symptoms: splenomegaly, hepatomegaly, enlargement of the lymph glands, amenia and purpura. Investigation: Thrombocytepenia, hypomemoglobin, hyperglobulin, HIV positive. Hypermacrophages were identified by microscopy in the born marrow smear: parasites in macrophages look like Amastigote of Leishmania parasites in the Atlas (The morphology of human blood cells- Abbott laboratories). Born marrow cultured in N.N.N medium: identified Promastigotes. Diagnosis: Visceral Leishmaniasis. It was confirmed by Karolinska hospital of Sweden, China, and Singapore. This is first case identified in Vietnam
Leishmaniasis, Visceral ; Leishmania donovani

No abstract available.
Leishmaniasis, Cutaneous*

Female ; Humans ; Infant ; Leishmaniasis, Visceral

Introduction: Cutaneous leishmaniasis is non-endemic in the Philippines. Antiparasitic pentavalent antimonials are acknowledged as first-line therapy for all forms of the disease. Amphotericin B is the second drug of choice but its use is limited due to side effects. Case Summary: We present a case of a 32- year-old male overseas Filipino worker who presented with “volcaniform plaques” (nodules and plaques with central crater) and surrounding satellite erythematous papules on the trunk, and extremities after returning from Iraq. A diagnosis of cutaneous leishmaniasis was confirmed by the histopathologic findings of a granulomatous inflammatory infiltrate with round to oval basophilic structures in the cytoplasm of macrophages (Leishman bodies) in the dermis, which were highlighted prominently by Giemsa stain. The patient showed poor response to treatment with 4 weeks of oral Rifampicin 1200 mg daily divided into 2 doses. He was shifted to oral Itraconazole 400 mg daily divided into 2 doses for 6 weeks with dramatic improvement. Conclusion This case report highlights the favorable therapeutic response of cutaneous leishmaniasis to oral itraconazole and hence, may be recommended as first-line medication to treat infected overseas workers from endemic areas who seek treatment in the Philippines.
Leishmaniasis

No abstract available.
Female ; Humans ; Leishmaniasis, Visceral* ; Lupus Erythematosus, Systemic*

No abstract available.
Cryotherapy* ; Leishmaniasis, Cutaneous* ; Metronidazole*

OBJECTIVES: Leishmania parasites are the causative agents of leishmaniasis. The Visceral leishmaniasis (VL) form of the disease is fatal if not treated in most cases. This study examined the epidemiological aspects of VL in two southwest counties of Iran. METHODS: This was a retrospective study of hospitalized patients with a laboratory confirmation of VL from Larestan and Ghiro-Karzin Counties. RESULTS: For Larestan county, a decline in the incidence of VL has been observed from 2004 to 2015. Significantly more males (n = 14) than females (n = 6) were infected with VL in this county (p < 0.05), >95% of cases in children under 5 years of age. In Ghiro-Karzin county, the results were similar to a decline in VL infection from 2004 to 2015, and slightly more males (n = 14) than females (n = 11). Similarly, the majority of the patients infected with VL were children under 5 years old (88%). CONCLUSION: The results from this study indicate that although the incidence of VL infection has reduced over time, VL was more prevalent in boys under 5 years old, suggesting that more attention to controlling the parasite and its vector are required.
Child ; Epidemiology ; Female ; Humans ; Incidence ; Iran* ; Leishmania ; Leishmaniasis ; Leishmaniasis, Visceral* ; Male ; Parasites ; Retrospective Studies

Adult ; Diagnosis, Differential ; Female ; Humans ; Leishmaniasis, Visceral ; diagnosis

International travel has become increasingly common as travelers of various purposes. It is estimated that there are 900 million international tourist arrivals alone each year. Unfortunately, some health impairments were reported in about 50% of short term travelers to the tropics or sub-tropics, usually due to infectious agents. In this paper, the author reviewed imported parasitic diseases in Korea from 1970 to 2009 with literature and data collected by Korea Centers for Disease Control and Prevention (KCDC). The author also reviewed warning points about parasitic disease in pregnant and immune deficit travelers. Most prevalent imported parasitic disease was malaria. About 30~70 travelers infected with malaria are returned home anually from abroad, mostly South East Asia and Africa. Subtype of malaria classified from 2003~2006 surveillance data showed Plasmodium falciparum infection in about 55% of patients identified. Over 20 cases of hydatid disease and cutaneous leishmaniasis cases were reported respectively. Visceral leishmaniasis (5 cases), babesiosis (7 cases), loiasis (3 cases), cutaneous myiasis (1 case), pentastomiasis (1 case), gnathostomiasis (4 cases, 41 people), angiostrongylosis (1 case, 10 people), heterophyiasis (2 cases), schistosomiasis (13 cases), cyclosporiasis (1 case), cutaneous larva migrans (4 cases), ancylostomiasis (1 case) and syngamosis (1 case) were reported. Prevention and surveillance plan of imported parasitic diseases is organized and conducted by KCDC since 2001. According to increasing travel to developing or under developed countries, retraining of doctor and technician, systematization of consulting system for diagnosis of parasitic disease, supply of medication, supplement of the personnel, and financial supports are needed.
Africa ; Ancylostomiasis ; Animals ; Babesiosis ; Centers for Disease Control and Prevention (U.S.) ; Cyclosporiasis ; Developing Countries ; Far East ; Financial Support ; Gnathostomiasis ; Humans ; Korea ; Larva Migrans ; Leishmaniasis, Cutaneous ; Leishmaniasis, Visceral ; Loiasis ; Malaria ; Myiasis ; Parasitic Diseases ; Plasmodium falciparum ; Schistosomiasis