No abstract available.
Hyperplasia* ; Leishmania donovani* ; Leishmania*

No abstract available.
Hyperplasia* ; Leishmania donovani* ; Leishmania*

No abstract available.
Bone Marrow ; Leishmania ; Leishmania donovani

No abstract available.
Bone Marrow ; Leishmania ; Leishmania donovani

Female patient, 29 age, married, lives in Ha Long. Admitted of hospital 16/03/2001. Reason for admitted hospital: prolonged fever symtoms: splenomegaly, hepatomegaly, enlargement of the lymph glands, anemia, purpura. Investigation: thrombocytopenia, hypohemoglobin, hyperglobulin, HIV positive. Hypermacrophages were indentidied by microsscopy in the bone marrow smear: parasites in macrophages look like Amastigote of Leishmania parasites in the atlas (the morphology of human blood cells- abbott laboratories). Born marrow cultured in NNN medium: identidied promastigote. Diagnosis: visceral Leishmaniaxsis. It was confirmed by Karolinska hospital of Sweden, China, Singapore, Australia. This is first case indentified in Vietnam
Leishmaniasis, Visceral ; Leishmania donovani

A female patient 29 years old, married, lived in Halong was admitted to hospital in 16/03/2001. Reason for admitting hospital: prolonged fever. Symptoms: splenomegaly, hepatomegaly, enlargement of the lymph glands, amenia and purpura. Investigation: Thrombocytepenia, hypomemoglobin, hyperglobulin, HIV positive. Hypermacrophages were identified by microscopy in the born marrow smear: parasites in macrophages look like Amastigote of Leishmania parasites in the Atlas (The morphology of human blood cells- Abbott laboratories). Born marrow cultured in N.N.N medium: identified Promastigotes. Diagnosis: Visceral Leishmaniasis. It was confirmed by Karolinska hospital of Sweden, China, and Singapore. This is first case identified in Vietnam
Leishmaniasis, Visceral ; Leishmania donovani

Two Korean men who had worked in Saudi Arabia complained of skin ulcers in the right wrist for 5 months or in the face and left forearm for 4 months each. Ulcers accompanying crust was observed in both cases. The characteristic cellular destruction and amastigote in the cytoplasm of histiocyte supported the diagnosis of cutaneous leishmaniasis. Those are 17th and 18th imported cases of cutaneous leishmaniasis in Korea(summarized from text).
parasitology-protozoa ; case report ; Leishmania donovani ; leishmaniasis ; Saudi Arabia

An imported case of Kala-azar in a 26-year-old Korean man is reported. The diagnosis was made by liver needle biopsy. Amastigotes were seen in Kupffer cells under light microscope, and their characteristic ultrastructural features were recognized under the electron microscope. This case represents an imported disease from Saudi Arabia where the patient spent one year as a construction worker, 8 months before the onset of the disease. This report also signifies the second description of Kala-azar in Korea, and the first case of Kala-azar imported from Saudi Arabia. This patient was successfully treated with sodium antimony gluconate (Pentostam), and follow up liver biopsy showed focal fibrous scar and otherwise normal liver without demonstrable organism.
parasitology ; protozoa ; Kala-azar ; Leishmania donovani ; case report ; Saudi Arabia ; electronmicroscopy

Animals ; Artemisinins ; pharmacology ; Cricetinae ; Leishmania donovani ; drug effects ; Male ; Mesocricetus ; Sesquiterpenes ; pharmacology

A patient with fever, chills, and pancytopenia as major clinical manifestations was presented. To investigate the cause, the patient's peripheral blood was collected for pathogen screening using metagenomic next - generation sequencing (mNGS). The DNA sequence of Leishmania donovani was detected, and Leishmania amastigotes were found in bone marrow smears using microscopy. The case was therefore definitively diagnosed as visceral leishmaniasis, and was cured and discharged from hospital following treatment with liposomal amphotericin B for 14 days. This is the first imported case of visceral leishmaniasis since the founding of Shenzhen City in 1979.
Humans ; Fever ; High-Throughput Nucleotide Sequencing ; Leishmania donovani/genetics* ; Leishmaniasis, Visceral/drug therapy*