Intravenous leiomyomatosis (IVL) is extremely rare with just around 300 cases reported in literature. 1 With its unusual growth pattern and clinically aggressive behavior, this benign tumor can masquerade as a malignancy and present a diagnostic challenge. Concurrent uterine fibroids or recent hysterectomy for the same often provides a hint towards the diagnosis. 2 The median interval between hysterectomy and diagnosis of IVL is approximately 4 years. 3 We present a case of IVL detected 10-years post total hysterectomy, bilateral salpingo-oophorectomy (THBSO) and parametriectomy with emphasis on multimodality imaging with multip
Leiomyomatosis

Leiomyomatosis peritonealis disseminata is a rare non-neoplastic proliferation of histologically benign smooth muscle that occurs in the alxlominal cavity of during the reproductive years of life, often giving rise to false choical imprwsion of d.isseminated carcinomatosis grossly, In 1952 Wilson & Peale described a condition which they called "multiple peritoneal leiomyomas". Taubert et al(1965) clearly delinated the features of the lesion and named it leiomyomatosis peritonealis disseminata(LPD). We report a case of leiomyomatosis peritonealis disseminata with a brief review of literatures.
Carcinoma ; Leiomyomatosis* ; Muscle, Smooth

Hydropic degeneration is a frequent degenerative change in otherwise typical uterine leiomyomas. Very rarely, however, a significant amount of edema fluid accumulates around the fascicles of neoplastic smooth muscle bundles and forms the characteristic multinodular growth pattern that is called perinodular hydropic degeneration of leiomyoma (PHDL). The gross findings, showing a vague worm-like appearance and very rarely having an extrauterine extension, and the microscopic features, showing perinodular retraction artifacts forming pseudovascular spaces, make it difficult to differentiate the tumor from intravenous leiomyomatosis or myxoid leiomyosarcoma. We described two cases of leiomyomas showing perinodular hydropic degeneration (PHD), a condition that has rarely been described in English literature, and discussed the mechanism of forming "extrauterine extension" or cotyledonoid features. One of our cases showed the typical features of cotyledonoid dissecting leiomyoma, the other showed those of intramural dissecting leiomyoma. An awareness of the gross and microscopic findings of PHDL is important not to overdiagnose a benign smooth muscle neoplasm as a more aggressive type of tumor. It is thought that intramural dissecting leiomyoma, cotyledonoid dissecting leiomyoma, and PHDL are not distinct, but closely related subtypes showing different phases of evolutionary changes.
Artifacts ; Edema ; Leiomyoma* ; Leiomyomatosis ; Leiomyosarcoma ; Muscle, Smooth

Though leiomyomas are the commonest benign tumors in the esohpagus, the vast majority of the leiomyomas of alimentary tract occurs outside the esophagus. Leiomyoma is mostly solitary, and multiple lesions are rare. Diffuse esophageal leiomyomatosis is a very rare disease, which is the condition having diffuse thickening of esophageal musculature and with or without discrete lesion. We are reporting a typical case of diffuse leiomyomatosis of the esophagus in a 37-year-old woman successfully resected.
Adult ; Esophageal Neoplasms ; Esophagus* ; Female ; Humans ; Leiomyoma ; Leiomyomatosis* ; Rare Diseases

Reed's syndrome is a rare, autosomal dominant disease with incomplete penetrance that is characterized by uterine and cutaneous leiomyomas. We report a case of Reed's syndrome in a 50-year-old woman. The patient underwent removal of the uterine leiomyoma at the age of 36. Following this the patient noticed development of multiple, cutaneous nodules on both arms at the age of 45. These nodules progressively increased in both number and size, while appearing in other sites. The histopathologic finding of an isolated, single skin lesion showed typical leiomyoma arising from arrector pilorum muscle. Familial history revealed that her father had been affected with similar cutaneous lesions.
Arm ; Fathers ; Female ; Humans ; Leiomyoma ; Leiomyomatosis* ; Middle Aged ; Penetrance ; Skin

Cutaneous leiomyoma is a benign tumor of smooth-muscle fibers. There are five types of cutaneous leiomyoma; multiple piloleiomyomas; solitary piloleiomyoma; solitary genital leiomyoma; solitary angioleiomyoma; and leiomyoma with additional mesenchymal elements. A 50-year-old woman had a 13-year history of variable sized painful eryhtematous papules and nodules on the left upper chest, shoulder, arm and back. These lesions were distributed in a zosteriform pattern and corresponded with the left fourth cervical and the left second thoracic dermatome. The histopathologic findings revealed typical piloleiomyoma. One case of zosteriform cutaneous leiomyoma has been reported in the Korean literature. However, the lesions of the case corresponded with two close dermatomes and developed widely. Such a case has never been reported in the Korean literature case.
Arm ; Female ; Humans ; Leiomyoma ; Leiomyomatosis ; Middle Aged ; Neck ; Shoulder ; Thorax

Intravenous leiomyomatosis (IVL) is rare and it is characterized by intravascular nodular masses of benign smooth muscle that may extend to variable site such as uterus, pelvic veins, inferior vena cava, right sided heart and eventually lung. We experienced an unusual case of IVL originating from the uterus and extending to the lung parenchyma and treated by combined surgery, so we report it with a brief review of the literatures.
Heart ; Leiomyomatosis* ; Lung* ; Muscle, Smooth ; Uterus ; Veins ; Vena Cava, Inferior

Leiomyomatosis peritonealis disseminata (LPD) is a rare condition characterized by multiple subperitoneal nodules of benign smooth muscle. Wilson and Peale were the first to describe the multiple peritoneal leiomyomas, while Taubert et al. clearly delineated the features of the lesion and named it LPD. Approximately 100 cases of this disease have been reported in the world literature. High levels of exogenous and endogenous female gonadal steroids is associated with LPD, it suggests that estrogen and progesterone play important role in the pathogenesis of LPD. We report a case of leiomyomatosis peritonealis disseminata with review of literature.
Estrogens ; Female ; Gonads ; Humans ; Leiomyoma ; Leiomyomatosis* ; Muscle, Smooth ; Progesterone ; Steroids

Leiomyomatosis peritonealis disseminata (LPD) is rare, typically benign condition characterized by multiple smooth muscle, myofibroblasticand fibroblastic nodules arising in the pelvic and abdominal cavities in women. LPD is observed in reproductive age group especially and often mimics carcinomatosis grossly but has benign histologic feature and good prognosis. We report a case of leiomyomatosis peritonealis disseminata arising after laparoscopic myomectomy with review of literature.
Abdominal Cavity ; Carcinoma ; Female ; Fibroblasts ; Humans ; Leiomyomatosis ; Muscle, Smooth ; Prognosis

Humans ; Consensus ; Leiomyomatosis/surgery* ; Pelvis/diagnostic imaging* ; China