1.A Rare Case of Intra-Endometrial Leiomyoma of Uterus Simulating Degenerated Submucosal Leiomyoma Accompanied by a Large Sertoli-Leydig Cell Tumor.
Kyungah JEONG ; Sa Ra LEE ; Sanghui PARK
Yonsei Medical Journal 2016;57(2):523-526
A 50-year-old peri-menopausal woman presented with hard palpable mass on her lower abdomen and anemia from heavy menstrual bleeding. Ultrasonography showed a 13x12 cm sized hypoechoic solid mass in pelvis and a 2.5x2 cm hypoechoic cystic mass in uterine endometrium. Abdomino-pelvic computed tomography revealed a hypodense pelvic mass without enhancement, suggesting a leiomyoma of intraligamentary type or sex cord tumor of right ovary with submucosal myoma of uterus. Laparoscopy revealed a large Sertoli-Leydig cell tumor of right ovary with a very rare entity of intra-endometrial uterine leiomyoma accompanied by adenomyosis. The final diagnosis of ovarian sex-cord tumor (Sertoli-Leydig cell), stage Ia with intra-endometrial leiomyoma with adenomyosis, was made. Considering the large size of the tumor and poorly differentiated nature, 6 cycles of chemotherapy with Taxol and Carboplatin regimen were administered. There is neither evidence of major complications nor recurrence during 20 months' follow-up.
Adenomyosis/*diagnosis/drug therapy
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Carboplatin/therapeutic use
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Female
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Humans
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Laparoscopy
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Leiomyoma/*diagnosis/drug therapy
;
Male
;
Menorrhagia
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Middle Aged
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Neoplasm Recurrence, Local
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Paclitaxel/therapeutic use
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Sertoli-Leydig Cell Tumor/*diagnosis/drug therapy
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Treatment Outcome
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Uterine Neoplasms/*diagnosis/drug therapy
2.A Case of SKull Bone Metastasis in Uterine Leiomyosarcoma.
Hyung Gi PARK ; Suk Mo KIM ; Ho Sun CHOI ; Ji Soo BYUN ; Jong Soon KIM ; Sang Woo JUHNG
Korean Journal of Obstetrics and Gynecology 1997;40(3):652-656
Uterine leiomyosarcoma is a rare malignant tumor, and distant metastasis to skull bone is very uncommon. We experienced a case of parietal skull bone metastasis from uterine leiomyosarcoma in a 52-year-old woman who had undergone simple total hysterectomy and bilateral salpingoophorectomy with the diagnosis of uterine myoma. We treated this patient with combination chemotherapy using cisplatin and adriamycin and radiotherapy after craniectomy. She is alive now without particular symptoms. We report this case with a brief review of some literatures.
Cisplatin
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Diagnosis
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Doxorubicin
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Drug Therapy, Combination
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Female
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Humans
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Hysterectomy
;
Leiomyoma
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Leiomyosarcoma*
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Middle Aged
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Neoplasm Metastasis*
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Rabeprazole
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Radiotherapy
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Skull*
3.Inflammatory myofibroblastic tumor of uterus: report of a case.
Yan-yan DONG ; Chong-xiao QU ; Yun-xiao LIU ; Li-ping ZHAO
Chinese Journal of Pathology 2012;41(6):412-413
Actins
;
metabolism
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Adult
;
Diagnosis, Differential
;
Female
;
Fibroma
;
pathology
;
Fibrosarcoma
;
pathology
;
Follow-Up Studies
;
Humans
;
Hysterectomy
;
Inflammation
;
Keratins
;
metabolism
;
Leiomyoma
;
pathology
;
Neoplasm Recurrence, Local
;
Neoplasms, Muscle Tissue
;
drug therapy
;
metabolism
;
pathology
;
surgery
;
Receptor Protein-Tyrosine Kinases
;
metabolism
;
Uterine Neoplasms
;
drug therapy
;
metabolism
;
pathology
;
surgery
;
Young Adult