1.A case of Turner syndrome with horseshoe kidney and right side duplication kidney with UPJO and double kidney cyst
Leibo WANG ; Changyong ZHAO ; Zhongyi ZHANG ; Yuanming SONG ; Daobing LI
Chinese Journal of Urology 2021;42(6):475-476
This paper reports a rare clinical case of 46 X, i(X)(q10)TS in a female patient with horseshoe kidney and right duplication kidney with renal pelvic and ureteral junction stenosis and double kidney cysts, secondary to right renal calculi and hydronephrosis. After open surgical treatment, the curative effect was definite, which effectively relieved the stenosis at the junction of the renal pelvis and ureter and relieved the clinical symptoms of the patient. The patient was followed up for 3 months and recovered well. When TS is combined with horseshoe kidney with UPJO, open pyeloplasty with partial isthmus and renal fixation are still classic surgical procedures.
2.Meta-analysis of randomized controlled trials on the efficacy of daikenchuto on improving intestinal dysfunction after abdominal surgery.
Lei ZHANG ; Yusheng CHENG ; Huizi LI ; Yufeng ZHOU ; Bo SUN ; Leibo XU
Annals of Surgical Treatment and Research 2018;95(1):7-15
PURPOSE: Intestinal dysfunction is one of the most common complications in patients after abdominal surgery. Daikenchuto (DKT), a traditional herbal medicine, is recently employed to improve postoperative intestinal dysfunction. The aim of this meta-analysis was to assess the efficacy of DKT in improving intestinal dysfunction after abdominal surgery. METHODS: PubMed, Embase, and the Cochrane library were systematically searched to identify randomized controlled trails (RCTs) in adult patients undergoing abdominal surgery, who were randomly distributed to administrate DKT and placebo. The primary outcomes included the time to first postoperative flatus or bowel movement. We used random-effects models to calculate summary mean differences (MDs) with 95% confidence intervals (CIs). RESULTS: Nine RCTs totaling 1,212 patients (618 in DKT, 594 in control group) were included in our study. Compared with control group, DKT can effectively improve postoperative intestinal dysfunction by shortening the time to first postoperative flatus (MD, −0.41; 95% confidence interval [CI], −0.66 to −0.16; P = 0.001) with significant heterogeneity (I2 = 71%, P = 0.004), and bowel movement (MD, −0.65; 95% CI, −0.97 to −0.32; P < 0.001) without significant heterogeneity (I2 = 40%, P = 0.14). Sensitivity analyses by indication of surgery and type of surgery yielded similar results. CONCLUSION: These data provide limited evidence that DKT shows efficacy on improving intestinal dysfunction after abdominal surgery. However, the results should be interpreted cautiously, due to the heterogeneity of the studies included. Thus, the efficacy of DKT on improving postoperative intestinal dysfunction warrants further investigation.
Adult
;
Flatulence
;
Herbal Medicine
;
Humans
;
Population Characteristics
3.A study of the expression of Fas after fluid percussion brain injury in rats.
Hong-fu PAN ; Ye WANG ; Xiao-gang CHEN ; Jing YANG ; Leibo LI ; Qiyi PENG ; Wendong WANG ; Min LIU
Journal of Forensic Medicine 2004;20(4):205-207
OBJECTIVE:
To study the pathologic diagnosis and the injury time estimation in light closed encephalon injury.
METHODS:
Mice were hurt by fluid percussion, and were killed at 15, 30 min, 1, 3 , 6, 12 h, 1, 4, 7, 14 d respectively after injury. The expression of Fas-L in the cerebral cortex, thalamus, and hippocampi was detected by immunohistochemistry and the results were assessed by image analysis system.
RESULTS:
It is showed that the expression of Fas-L could be detected in 1 h after injury, and increased significantly in three hours, and it reached apex 12 h after injury, and decreased gradually four days after injury, and returned normal 14 days after injury.
CONCLUSION
This research demonstrated that Fas-L mediated apoptosis appeared not only around brain trauma but also in the brain tissue far away from the traumatic area. It indicted that the expression of Fas-L is a useful target for diagnosis of early brain injury; the regularity of Fas-L expression could be used as one of indication to date the time of brain injury.
Animals
;
Apoptosis
;
Brain/metabolism*
;
Brain Injuries/pathology*
;
Fas Ligand Protein
;
Image Processing, Computer-Assisted
;
Immunohistochemistry
;
Male
;
Membrane Glycoproteins/biosynthesis*
;
Rats
;
Rats, Wistar
;
Time Factors
;
Tumor Necrosis Factors/biosynthesis*