Dental Implants ; Dental Prosthesis Design ; trends ; Humans

Dental Implantation, Endosseous ; Dental Implants, Single-Tooth ; Humans ; Maxilla ; surgery

Objective　To investigate the causes of recurrent spontaneous abortion(RSA) and to know the relation between RSA and antiphospholipid thrombosis syndrome(APL-T). Methods　ELISA and PTT-LA were used to detect anticardiolipin antibody(ACA) and lupus anticoagulant(LA) in 32 patients with RSA and 20 normal controls(NC). Results　There were 17 positive of antiphospholipid antibody(APA) in RSA group. The incidence was significantly higher than that in NC group. The incidence of LA was also significantly higher than that in NC group. 8 patients were diagnosed as APL-T. Conclusion　LA may be the more important reason of RSA. It should be considered as APL-T when RSA is unexplained.

Granzyme B is an important effect factor of cytotoxic T lymphocytes in the immune killer function,can quickly induce cell apoptosis of the target cell.It is complicated for the reasons and the ways of the occurrence of the cell apoptosis,many genes are involved in gene regulation of cell apoptosis,and the B-cell lymphoma/leukemia-2 gene family members play a crucial role in the process of cell apoptosis.This paper mainly reviews the correlation of GrB and Bcl-2,Bid with cell apoptosis.

Serine proteinase inhibitor9(P1-9),a charac-teristic member of serpins,has been identified as the only inhibitor of granzyme B(GrB).Accumulated evidence suggested that PI-9 inhibits GrB-induced apoptosis by blocking DNA fragmentation of target cell.Physiologically,PI-9 could protect cytotoxic lymphocytes from committing autolysis or fratricide,and play an important role in facilitating immunologic tolerance of immune-privileged sites.In addition,evidences in recent years suggest that PI-9 Was also involved in vailous pathologic processes,such as inflammation,trans plantation and immune tolerance of tumor.

Objective: To view the characteristics and the primary treatment of civilian firearm wound in the maxillofacial region.Methods: 301 cases of the casualties admitted to our hospital were retrospectively investigated,the epidemic, etiology, wound characteristics, and treatments of the patients were viewed respectively. Results: Of all the cases, the ratio of male to female was 5.1∶1.0. 57% of the injuries were caused by gunshot, 66% were with multiple injuries.16% combination wound were craniocerebral injuries. In this group of patients, more than 900 wound tracks were found, 72% of the tracks were nonpenetrating and 67% of those were with foreign bodies lodged in. Burns with blast injuries were the main complex wounds, which mostly occurred in explosion. The treatments mainly included life maintaining, earlier debridement and infection control. Conclusions: The maxillofacial firearm injuries are complex and have their own characteristics depending on the firearms, the wound styles and the regional anatomy. All the factors must be considered when treatment is given.

Child, Preschool ; Foreign Bodies ; surgery ; Humans ; Intestines ; Laparoscopy ; methods

Objective To know about care experience and medical care demands of caregivers of retinopathy of prematurity children in order to provide reference for clinic. Methods A total of 11 caregivers were interviewed by qualitative research methodology. Data and subjects were refined by Colaizzi methodology. Results Totally 3 subjects about care experience were extracted, which were high psychological pressure, heavy caregiver burden, desire for medical and nursing support. Conclusions Medical care personnel should improve treatment system of retinopathy of prematurity and provide information and psychological support in order to improve quality of life of children.

Co-citations of highly cited papers on gene annotation covered in Web of Science were analyzed by clustering analysis using clustering software after the word matrix of resource literature and highly cited papers was formed, which showed that the application of text mining on gene annotation includes use of authorized tools, development of text mining tools and algorithms, and verification of text mining tools.

To research the risk factors of portal vein thrombosis( PVT) in liver cirrhosis patients. 110 cirrhotic pa-tients with ( n =39 ) or without ( n =71 ) PVT diagnosed were enrolled. 12 common ultrasonographic and serum markers were analyzed. SPSS software was used for statistic analysis. Single factor analysis and Logistic regression model analysis showed that fibrinogen was the independent risk factor of portal vein thrombosis( PVT) in liver cir-rhosis patients. Fibrinogen should be monitored in patients with cirrhosis to prevent and find the occurrence of portal vein thrombosis.