The deficiencies in reading popularization at present were analyzed, the concepts of liberal education and liberal platform were described, and the successful experiences in liberal platform-based reading popularization in academic libraries were summarized, such as experiencing human library by stressing on communication between users, achieving the reading and education effect by applying the liberal concept, selecting reading materials based on the needs of teachers and students, and establishing special reading popularization team.

The contents, methods and commons of social information service in Markerere University Library were analyzed according to the social information service in domestic academic libraries and the enlightenments on extending social information service in domestic academic libraries were elaborated, such as active participating in study of social problems and attaching importance to librarians training .

OBJECTIVE:To study the mechanism that apoptosis of NB4 cells were induced by artesunate. METHODS: The apoptosis of NB4 cell induced by artesunate was determined by Annexin V-FITC FCM analysis and cytomorphology and the activity of Caspase-3 was determined by ELISA assay. RESULTS: Artesunate could induce apoptosis of NB4 cell with the activity of Caspase-3 increasing. CONCLUSIONS: The apoptosis of NB4 cell induced by artesunate is achieved by activating Caspase-3.

Objective Compared with surgical operation,to investigate the clinical efficacy and advantages of interventional treatment in blunt liver traum.Methods 32 patients from July 2010 to October 2012,who were diagnosed as blunt liver trauma,received super selective hepatic artery embolization in Chinese People's Liberation Army in 98th Hospital.Another 27 ones received operation at the same time in Peolies's Liberation Army 98th (AAST grade Ⅱ to Ⅳ).Retrospective analysis of related cases was presented.The results were analyzed by t test.Results All of 32 patients that received super selective hepatic artery embolization were stanched bleeding successfully.All patients were followed up for 3 to 18 months,the mean follow-up time was 10 months,with no severe complications occurred or no lost cases.Conclusions Compared with surgical operation,interventional treatment had advantage that included eliable hemostasis,less operation time,minimally invasive and less hospitalization time.Interventional treatment had good effects on blunt liver trauma which were AAST grade Ⅱ to Ⅲ.

Acupuncture Therapy ; instrumentation ; Adolescent ; Adult ; Aged ; Facial Paralysis ; therapy ; Female ; Humans ; Male ; Middle Aged ; Young Adult

BACKGROUND:The effect of placenta-derived growth factor(PLGF)on promoting vascular regeneration remains uncertain.In studies of models with PLGF deletion,PLGF has been considered to play critical role in inducing angiogenesis.OBJECTIVE:To summarize the research advances in effect of PLGF and its receptor in vascular regeneration and ischemic cerebral disease.METHODS:A computer-based online search of Pubmed and CNKl was performed for relevant articles published between 1990 and 2009 with key words of"PLGF"in Chinese and"PLGF angiogensis"Articles related with biological characteristics of PLGF and its roles in vascular regeneration and articles related with angiogenesis and PLGF expression after cerebral ischemia were selected.Repetitive articles were excludedRESULTS AND CONCLUSION:The role of PLGF and its receptor in vascular regeneration,mechanism of PLGF and its receptor to promote angiogenesis,vascular endothelial growth factor A,and the expression of PLGF and its receptor in brain after cerebral ischemia were introduced.PLGF can promote pathological angiogenesis,arteriogenesis,branch formation and hemopoietic progenitor cell mobilization.PLGF and its receptor play an important role in the angiogenesis of ischemic cerebral disease and display a good clinical prospect in the treatment of ischemic cerebral disease However,the specific role and mechanism require further study.

Alzheimers disease(AD) is one of dementia diseases in the world. There are two main pathological hallmarkers in AD patients, one is ?-amyloid peptide, the other is neurofibrillary tangles. This paper reviews researches on targets for drug discovery for Alzheimers disease that had been supported by the National Nature Science Foundation of China in recent ten years.

In cardiomyocytes,sodium-calcium exchanger(NCX) is regarded to play an important role in the regulation of intracellular Ca~(2+) concentration.During the cardiac ischemia/reperfusion or cardenolide intoxication,the inflow Ca~(2+) through NCX reverse mode induce calcium overload and arrhythmia.Recently,the benzyloxyphenyl derivatives have been developed as selective NCX inhibitors,which may have therapeutic potential as a new remedy for arrhythmias.

OBJECTIVE:To evaluate the economics of Yindan xintai dropping pills in the treatment of angina pectoris caused by coronary heart disease from societal perspectives. METHODS:Therapy regimens related to Yindan xintai dropping pills and con-trol regimens were selected from published literatures included in database,and the cost of therapy regimens and clinical effect data were extracted from literatures. Contingent evaluation method was used to measure people's willingness-to-pay for angina pectoris treatments. An econometric model was conducted to transfer the effectiveness data to benefit data. The economics of treatment was evaluated depending upon net benefit or incremental net benefit indicator. RESULTS & CONCLUSIONS:When Yindan xintai drop-ping pills is used alone,its net benefit is >0,indicating economical advantage;56 d therapy regimen is better than 28 d therapy. When Yindan xintai dropping pills were combined with glyceryl trinitrate tablet,Isosorbide mononitrate sustained-release tablet, Simvastatin dispersible tablet and other drugs,its incremental net benefit is better than control regimens and has good economics.

Objective To compare the clinical efficacy between Jian Huan Tong Tiao needling (acupuncture at both healthy and affected sides) and acupuncture at the affected side alone in treating peripheral facial paralysis (FP) in acute stage, and to provide evidences for the acupuncture treatment of peripheral FP in acute stage.Method Fifty patients were randomized into a Jian Huan Tong Tiao needling group (25 cases) and an affected side needling group (25 cases). By selecting the same acupoints, the Jian Huan Tong Tiao needling group received acupuncture at both sides, while the affected side needling group received acupuncture only at the affected side, once every other day, successively for 4 weeks. House-Brackmann (H-B) facial nerve grading system was used to score the facial nerve function before and after the treatment, and the therapeutic efficacies were compared between the two groups.Result The facial nerve function was improved in both groups, while the therapeutic efficacy was superior in the Jian Huan Tong Tiao needling group to that in the affected side needling group (P<0.05); after 2-week treatment, the H-B score was higher in the Jian Huan Tong Tiao needling group than in the affected side needling group (P<0.05); of the recovered cases, the relapse rate was lower in theJian Huan Tong Tiao needling group than in the affected side needling group (P<0.05). Conclusion Jian Huan Tong Tiao needling can boost the recovery of the facial nerve function in peripheral FP, reduce the relapse rate, and produce a higher therapeutic efficacy than needling the affected side alone.