1.Skill validation study on sentinel lymph node biopsy in breast cancer and the challenges of false-negative, in-transit and micrometastatic nodes
Chen Siew Ng ; Sarojah Arulanantham ; Joon Joon Khoo ; Subathra Sabaratnam ; Yeong Fong Lee ; Chin Fang Ngim
The Medical Journal of Malaysia 2016;71(5):275-281
2.The Outcome Of A Calculated Radioiodine Dose Based On Pertechnetate Thyroid Uptake Ratio In Treatment For Hyperthyroidism
Malaysian Journal of Medicine and Health Sciences 2018;14(Supplement 1):71-75
Introduction: There are two dosing methods for radioiodine dose administration including empirical fixed dose and calculated dose. Recent meta-analysis supported that dose calculation is better than empirical fixed dose. However, dose calculation by dosimetry or 24 hours radioiodine uptake ratio can be tedious. Pertechnetate thyroid scintigraphy is a simple nuclear imaging that can be completed on the same day and pertechnetate thyroid uptake ratio determined from the scintigraphy can be used to calculate the radioiodine dose. This research is done to measure the efficacy of the calculated dose regime. Methods: Hyperthyroidism patients referred for first radioiodine therapy were recruited. Pertechnetate thyroid scintigraphy was done and pertechnetate uptake ratio used for dose calculation. The outcome of the treatment was determined at six months. Results: A total of 95 patients were recruited. Six months after treatment, 82.1% of the calculated dose cohort achieved euthyroid or hypothyroid state. Participants with multinodular goitre had higher failure rate than those with Graves’ disease (p=0.032) although there was no difference in the median RAI dose given (p=0.866). Conclusion: This calculated dose method showed good outcome with 82.1% cure rate at six months post treatment.
Hyperthyroidism
3.Correction to: Bone Scintigraphy and Tenofovir-Induced Osteomalacia in Chronic Hepatitis B
Alex Cheen Hoe KHOO ; Yeong Fong LEE
Nuclear Medicine and Molecular Imaging 2019;53(1):71-71
The original version of the author names was incorrect. The correct information is given above.
4.Bone Scintigraphy and Tenofovir-Induced Osteomalacia in Chronic Hepatitis B
Alex Khoo Cheen HOE ; Lee Yeong FONG
Nuclear Medicine and Molecular Imaging 2017;51(2):195-196
Tenofovir, used in the treatment of chronic hepatitis B and HIV, is known for its side effects on the kidneys and bones. We share interesting images of a patient with tenofovir-induced osteomalacia on Technetium-99 m hydroxymethyelene (Tc-99 m HDP) bone scintigraphy. Pattern recognition of this bone scintigraphy and correlation with the clinical history is essential to avoid misdiagnosis.
Diagnostic Errors
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Hepatitis B
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Hepatitis B, Chronic
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Hepatitis, Chronic
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HIV
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Humans
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Kidney
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Osteomalacia
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Radionuclide Imaging
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Tenofovir
5.Correction to: Bone Scintigraphy and Tenofovir-Induced Osteomalacia in Chronic Hepatitis B
Alex Cheen Hoe KHOO ; Yeong Fong LEE
Nuclear Medicine and Molecular Imaging 2019;53(1):71-71
The original version of the author names was incorrect. The correct information is given above.
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