2.Rhabdomyoma of the Orbit: A report of a case.
Kyungja CHO ; Hyun Soon LEE ; Je G CHI ; Hum CHUNG
Korean Journal of Pathology 1986;20(1):125-131
The patient was a 7 months old Korean girl, who was admitted to Department of Ophthalmology of the Seoul National University Hospital, with 6 months history of the left eyelid swelling and exophthalmos. Visual acuity and ocular movement were unaffected. Orbit CT revealed 1.5x.5 cm sized well circumscribed intraconal mass in the left retrobulbar space with pressure erosion of adjacent bone. At surgery, the mass was pinkish gray and firm, and was adherent to adjacent tissue. The whole mass could not be removed, and a local excision was done.
3.Molecular genetic study of primary malignant brain tumors:loss of heterozygosity on chromosome 10, 13q, 17q and 22q.
Seung Hoon LEE ; Jong Hyun KIM ; Chang Hoon LEE ; Young Soon KANG ; Je Ho LEE
Journal of the Korean Cancer Association 1993;25(5):717-724
No abstract available.
Brain*
;
Chromosomes, Human, Pair 10*
;
Molecular Biology*
4.The Pattern of Self Reported Assessment(Alcohol Use Inventory and Michigan Alcohol Screening Test) according to Receptive and Awareness of Drinking Problem and the Relation to the Alcoholic Type.
Myoung Ju LEE ; Soon Whoan PARK ; Hyun Je LEE
Journal of Korean Neuropsychiatric Association 2001;40(1):12-22
OBJECTIVES: This Study was designed to investigate the pattern of AUI(Alcohol Use Inventory) and MAST(Michigan Alcohol Screening Test) according to the awareness of drinking problem and receptiveness to treatment, and to know whether the type(type1 and type 2 according to Barbor's typology) has effects on the RECPAWAR(acknowledgement and awareness of use problem and receptive to treatment of these problem) score. METHODS: Subjects were 134 alcoholic patients from Alcoholic treatment ward. They were requested to fill up the questionnaires of Korean version of AUI and MAST(MAST for patient and MAST for caretaker). At first, based on the RECPAWAR, they divided into high RECPAWAR group(above 30 percentile) and low RECPAWAR group(below 30 percentile). According to typology, they divided into type 1 and type 2. The data was analyzed by T-test, Correlation, and Regression Analysis. RESULTS: 1) Significant negative correlation was observed between RECPAWAR score and MAST difference score(patient's MAST-caretaker's MAST). 2) High RECPAWAR group had significantly higher scores in the most scales than low RECP-AWAR group, except ENHANCED scale in AUI. 3) There was not significant difference on RECPAWAR score between type 1 and type 2. CONCLUSION: Except ENHANCED scale, the high RECPAWAR group had higher score in the second level scale. As compared with the low RECPAWAR group, the high RECPAWAR group responds more negative in drinking, and is more anxious about their drinking problems. So, they seem to have the objective view about their drinking problems. However the type was not related to receptive and awareness of drinking problem.
Alcoholics*
;
Drinking*
;
Humans
;
Mass Screening*
;
Michigan*
;
Surveys and Questionnaires
;
Self Report*
;
Weights and Measures
5.Congenital Systemic Cytomegalic Inclusion Disease.
Dong Beom LEE ; Dong Hyun KIM ; Jung Sik MIN ; Chang Hee CHOI ; Je Geun CHI
Journal of the Korean Pediatric Society 1990;33(1):100-106
No abstract available.
Cytomegalovirus Infections*
6.Brain Stem Glioma (An autopsy case).
Doo Hyun CHUNG ; Soong Deok LEE ; Hee Jin YANG ; Dae Hee HAN ; Je G CHI
Korean Journal of Pathology 1991;25(6):607-610
We report an autopsy case of the brain stem glioma that extended extensively in the brain stem itself and cephalad. This 18-year-old boy first presented with dizziness, vomiting and left side weakness with left facial palsy. Brain MRI revealed a diffusely infiltrative tumor involving whole medulla, pons and lower midbrain. A total of 4000 R was given with some alleviation of respiratory difficulty. He died one year after the onset. Autopsy revealed the tumor involving pons, a portion of medulla oblongata, and cerebellum. The tumor showed diffusely infiltrative pattern and extended along the periventricular area to the thalamus and corpus callosum. The cut surface was grayish white and solid. It also showed areas of myxoid degeneration and necrosis probably related to radiation therapy. Microscopically the tumor was a cellular and pleomorphic glioma that showed some astrocytic differentiation. It was diffuse without geographic necrosis.
7.Epithelial-Myoepithelial Carcinoma of Intercalated Duct of Parotid Gland.
Soong Deok LEE ; Doo Hyun CHUNG ; Sung Hye PARK ; Chul Woo KIM ; Je G CHI
Korean Journal of Pathology 1992;26(1):76-81
Epithelial-myoepithelial carcinoma of intercalated duct(origin) is a recently described tumor characterized by its typical biphasic pattern of central duct like cell and peripheral clear cell. We described a case of epithelial-myoepithelial carcinoma in a 10-year-old boy. Microscopically, the tumor showed typical biphasic pattern, diffuse proliferation of clear cells and linining epithelial cells of tubular structures. Immunohistochemically, the clear cell showed positive reaction to S-100 protein, and the epithelial cells expressed cytokeratin indicating myoepithelial and epithelial differentiation respectively. Biphasic differentiation of the tumor cells could be also proved by electronmicroscopic study.
8.Liposarcoma in the Extremity.
Soo Hyun LEE ; In je CHO ; Woo Ick YANG ; Jin Suck SUH ; Kyoo Ho SHIN
The Journal of the Korean Bone and Joint Tumor Society 2010;16(2):62-68
PURPOSE: We analyzed disease free survival and the prognostic factors of liposarcoma in the extremity. MATERIALS AND METHODS: Between 1994 and 2005, of 44 patients who were diagnosed and treated for liposarcoma of the extremity, 40 patients were restrospectively analysed. 13 out of 40 patients got postoperative radiotherapy. We examined local recurrence, distant metastasis and disease free 5-year survival rate. We also analyzed clinical prognostic factors, such as age, gender, size of tumor, prior unplanned excision, histologic type, surgical excision margin and postoperative radiotherapy respectively. RESULTS: There were 3 cases of local recurrence and 4 cases of distant metastasis. The disease free 5-year survival rate was 85.0%. 26 patients presented with myxoid, 8 well differentiated, 4 round cell, 1 pleomorphic and 1 dedifferentiated histology. The disease free 5-year survival rate of mixoid, well differentiated and round cell liposarcoma were 100.0%, 84.6% and 75.0% (p=0.419). The 5-year disease free survival rate was 90.6% in negative surgical margin (n=25) and 62.5% in positive surgical margin (n=15) (p=0.003). CONCLUSION: Our study suggests that surgical excision margin is significant prognostic factor for 5-year disease free survival rate.
Disease-Free Survival
;
Extremities
;
Humans
;
Liposarcoma
;
Neoplasm Metastasis
;
Recurrence
;
Survival Rate
9.THE APPROACH OF SKULL BASE LESIONS IN THE VIEW POINT OF PLASTIC SURGERY.
Myung Jong LEE ; Dong Hyun KIM ; Eul Je CHO ; Suk Choo CHANG ; Han Kyu KIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1997;24(3):559-569
Skull base surgery has developed through the evolution of imaging, anatomic research, surgical approach and reconstructive techniques. The basic disciplines of approaching skull base lesions are provide direct vision, minimizing brain retraction, excellent exposure and minimal blood loss. The focus of this report is to review the advantages of skull base approach in our cases and suggest some indications. We experienced 20 cases of skull base surgery by a team approach consisting of a neurosurgeon and plastic surgeon. The surgical approach were supraorbital osteotomy(5 case), orbitozygomatic osteotomy(8 case), orbitozygomaticoglenoid osteotomy (5 case ) and orbitozygomaticoglenoidocondylar osteotomy (2 case). In our experience, these approaches provided excellent exposure of the lesion, direct access to lesions and minimal brain retraction thereby better outcome.
Brain
;
Osteotomy
;
Skull Base*
;
Skull*
;
Surgery, Plastic*
10.The One-Year Prognostic Value of the Pre-Discharge ECG after the First Acute Myocardial Infarction.
Yeong Ho CHOI ; Suck Koo CHOI ; Won Sang YOO ; Hyun Je LEE
Korean Circulation Journal 1988;18(1):41-47
To assess the prognostic value of the 14 ECG variables obtained from the pre-discharge ECG, 35 patients were followed up for at least one year among the 80 patients of the acute myocardial infarction admitted at Seoul Paik Hospital from Sep. 1983 to Aug. 1986. The following results were obtained. 1) The overall in-hospital mortality rate was 20% and the mortality rate tended to decline year by year. 2) The one-year mortality and morbidity rate of the followed patients was 31.4%. 3) Among the 14 variables obtained from the pre-discharge ECG, T-negativity was the only statistically significant (p<0.05) one to predict the one-year prognosis in the patients after the first myocardial infarction, and we could not derive any meaningful datd from the analysis of the combined effects of the three ECG variables (PTF, ST depression and ST elevation).
Depression
;
Electrocardiography*
;
Hospital Mortality
;
Humans
;
Mortality
;
Myocardial Infarction*
;
Prognosis
;
Seoul