1.Dosage of celebroxib in drug products by method of capllary electrophoresis
Pharmaceutical Journal 2004;0(10):16-20
By the method of capillary electrophresis with MEKC technique on the preparation without processing of samples such as celebrex, zycel. The procedure of quantifisation of celebroxib was established. Statintrics results found that after 6 times of electrophresis the Corr Area ratio between celebroxib and our standards gave RSD ≤ 3% and t/t is ≤ 2%. Thus the procedure altained systematic compatibility for quantifying the preparation. The method had high sensitivity and selectivity. The results was precis and repeatable
Pharmaceutical Preparations/administration & dosage
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Methods
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Electrophoresis
2.Isolation and toxicity of Xanthomonas oryzae pv. oryzae in rice and a collection of phages against the pathogen
Ngoc Quynh Anh Pham ; Vo Thanh Phuc ; Pham Do Tra My ; Le Thi My Duyen ; To Hue Ngoc ; Nguyen Minh Thien ; Nguyen Hai Duong ; Le Thi Thuy Tien ; Le Phi Nga ; Hoang Anh Hoang
Malaysian Journal of Microbiology 2024;20(no.1):15-23
Aims:
The objective of the study was to isolate bacteriophages and conduct a comprehensive analysis of their potential against Xanthomonas oryzae pv. oryzae (Xoo) strains in the Mekong Delta, Vietnam.
Methodology and results:
Twelve Xoo strains were isolated from rice fields located in the Mekong Delta, Vietnam. Among these strains, three strains Xoo L019, L020 and L024, showed the highest disease index of bacterial blight. Four
phages specific to Xoo were isolated from soil, water and leaf samples, and their morphologies were determined. In a test against 12 Xoo strains, phage L541, MLA23 or W41 could infect 10 of the 12 Xoo strains, while phage LBH01 could infect 8 of the 12 Xoo strains. The stability of the phages to pH, organic solvents, UV-A and UV-B was also evaluated.
Conclusion, significance and impact of study
The initial characterization of the phages indicates their potential as biocontrol agents against bacterial blight in rice. The study is one of the very first studies about Xoo phages in rice in Vietnam.