Nosocomial pneumonia is a leading type of respiratory infection among hospital-acquired infections. Despite the introductions of new antibiotics, nosocomial pneumonia is associated with high morbidity and mortality. Among 80 patients aged more than 60 years old with nosocomial pneumonia, 17 patients (21.3%) received initial adequate therapies, 63 patients (78.7%) received initial inadequate therapies. Nosocomial pneumonia is often difficult to treat because of multi-resistant bacteria. Initially adequate antibiotic regimens are major prognostic factor for patients with nosocomial pneumonia. 3rd generation cephalosporines and fluoroquinolones aren’t effective. Imipenem, Timentin, Tazoncin, Cepfepim plus Amikacin and Vancomicin (if suspected bacterium is S. aureus) can be initial effective antibiotics
pneumonia

An prospective study was carried out on 101 patients over 60 years of age with pneumonia at Thong Nhat hospital from January 2004 to June 2005. The result showed that: 87.1% of pneumonia caused by negative-gram aerobes, among which P.aeruginosa accounted for 55.4%, K. pneumonia 55.4%, Acinetobacter 14.9%. 15.8% of pneumonia caused by positive-gram aerobes. Negative-gram aerobes were resistant strongly to third generation cephalosporin and fluoroquinolones, only sensitive to imipenem. S.aureus was resistant to oxacillin (87.5%) and sensitive to vancomicin
Pneumonia ; Bacteria ; Adult

Intersect description and processing data according to medicine statistics on 30 patients from 12/2003 to 9/2004 at Thong Nhat hospital. Result show that: Making pneumonia bacteria at Thong Nhat hospital are major bacillus (-), pseudomonas aeruginosa (83,3%), Klebsiella pneumonia (43,3%), Staphylococcus aureus (16,7%), Acinetobacter (6,7%). The bacteria is strong resistance to large spectrum antibiotic. There are 4 species of Psedomomas aeruginosa and 1 of Klebsiella pneumonia resist to all antibiotic newly used. Pathogenic multibactera is 60%.
Bacteria ; Pneumonia ; Epidemiology

A prospective study on 80 patients over 60 years old who were diagnosed hospital pneumonia at Thong Nhat hospital from December 2003 to April 2005. Results: hospital pneumonia by multi-bacteria was 55%. The common bacteria were K.pneumonia (56.25%); P.aeruginosa (55.0%); Acinetobacter (18.75%) and S.aureus (15%). The resistance level of bacteria caused hospital pneumonia: P.aeruginosa resisted most of antibiotics except Imipenem and Timentin (recently used in hospitals) with sensitive rate of 66.13% and 65%, respectively. K.pneumonia was sensitive only with Imipenem at the rate of 96.55%, Amikacin 66.91%. S.aureus resisted penicilin and most of other antibiotics; it was sensitive only with vancomicin at the rate of 100%. In relapsing or unsuccessful patients, the resistance of bacteria was stronger than the first time isolation.
Pneumonia, Bacterial ; Drug Resistance ; Therapeutics

In this study, 80 hospital acquired pneumonia patients ≥60 years old (59 males, 21 females) were treated in Thong Nhat Hospital of HCM city from December 2003 to April 2005. The results: mortality rate of hospital acquired pneumonia in the elderly patients was high, accounted for 43.75%. Invasive mechanical ventilation, long-term endotracheal intubations, endotracheal reintubation increased risk of death. Multi-organ failure, liver failure, kidney failure, gastrointestinal bleeding, shock, unconsciousness and diabetes increased fatal risk of disease. Serious prognostic factor included: no regress of fever, increase of leukocyte after 10 days of treatment, no improvement of PaO2/FiO2 ratio after 3 days of treatment.
Pneumonia ; Adult ; Clinical Medicine