1.Clinical Observations on Treatment of Hip Osteoarthritis by Electroacupuncture
Xiao ZHENG ; Tao CHE ; Le KUAI
Journal of Acupuncture and Tuina Science 2005;3(2):52-54
To investigate the curative effect of electroacupuncture on hip osteoarth-ritis, 120patients with hip osteoarthritis were randomly divided into two groups, 60 cases each group, and treated by electroacupuncture and oral administration of slow released diclofenac tablet,respectively. The degrees of pain, activity and swelling were observed in both groups before and after treatments. A follow-up was performed for more than 2 years. The curative effects were assessed by JOA criteria for evaluating the effect on hip osteoarthritis. After treatment, the average score increased by 18 marks in the electroacupuncture group and by 12.3 marks in the diclofenac group (P<0.05). Electroacupuncture treatment has a significantly better effect on hip osteoarthritis than oral administration of slow released diclofenac tablet.
2.The Expression and Significance of VEGF and MMP-9 in Non-small Cell Lung Cancer
Tao LIN ; Yongkui ZHANG ; Hanbo LE
Chinese Journal of Prevention and Control of Chronic Diseases 2006;0(03):-
Objective To determine the expression of Vascular Endothelial Growth Factor(VEGF) and Matrix Metalloproteinases-9(MMP-9) in non-small cell lung cancer(NSCLC) specimens and try to find out the possible roles of VEGF and MMP-9 in the invasion and metastasis of NSCLC.Methods Immunohistochemical SABC method was used to detect the expression of VEGF and MMP-9 in 23 non-cancerous pulmonary diseases tissues,30 normal lung tissues near the NSCLC and 111 NSCLC tissues.Results The expression levels of VEGF and MMP-9 in the NSCLC tissues were significantly higher than those of the control groups(P
4.Analysis of the Prevalence and Economic Burden of Diabetes in Guandu District of Kunming
Rong HE ; Le CAI ; Jun DONG ; Jie TAO ; Shulan ZHANG
Journal of Kunming Medical University 2014;(1):12-14
Objective To analyze the prevalence and economic burden of diabetes in Guandu district of Kunming. Methods We used probability proportional to size (PPS) sampling method to select representative sample of 4595 residents aged 18 or over from this district. Each participant received face to face questionnaire interview and physical examination. We applied different methods to measure the direct,indirect and intangible costs of diabetes. Results In the study population, the overall prevalence of diabetes was 6.2%,and females had higher prevalence of diabetes than males (6.2%vs. 5.6%, <0.05) . The DALY/1000 population of diabetes was 3.52, among which males and females were 5.18 and 6.70, respectively. Mean unit direct costs, indirect costs and intangible costs of diabetes were 3464.49 Yuan,84.48 Yuan and 4 045.97 Yuan,respectively. The total economic burden of diabetes was 401.84 million Yuan. Intangible costs represented the largest component of economic burden of diabetes,followed by direct costs. Conclusion The huge economic burden of diabetes has become the cause for concern in Guandu district. Effective measures are needed to reduce the economic burden of diabetes.
6.Meta-analysis of the effect of low-frequency repetitive transcranial magnetic stimulation on paretic hand recovery after stroke.
Qu LE ; Yun QU ; Shoujuan ZHU ; Yingxia TAO ; Yi LI
Journal of Biomedical Engineering 2013;30(6):1229-1234
Low-frequency repetitive transcranial magnetic stimulation (rTMS) is a non-invasive brain stimulation method that has been used in the treatments of stroke patients. Our purpose was to investigate the effects of low-frequency rTMS on the hand motor function recovery for stroke patients. After searching from electronic database from January 1990 to April 2012, we collected randomized controlled trials explored the low-frequency rTMS effects on the hand motor function rehabilitation. A total of 7 comparisons (N = 216) from 5 articles were included in this study. We summarized the effect size by calculating the standardized mean difference (SMD). Summary of effect size (SES) indicated positive effects of low-frequency rTMS on the finger motor ability (SMD = 0.58) and hand function (SMD = -0.98). Few adverse effects occurred. The evidence showed that low-frequency rTMS could improve the paretic hand recovery after stroke.
Hand
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physiopathology
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Humans
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Recovery of Function
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Stroke
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therapy
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Transcranial Magnetic Stimulation
7.Expression of human protection of telomere 1 and its relationship with Helicobacter pylori infection in gastric carcinoma
Fang YUAN ; Chunming LI ; Lifeng WANG ; Tao LE ; Hongqiu HE
Cancer Research and Clinic 2016;28(3):165-168
Objective To determine the expression of human protection of telomeres 1 (hPOT1) and its relationship with Helicobacter pylori (HP) infection in gastric carcinoma.Methods The expressions of hPOT1 protein and hPOT mRNA were detected in 53 gastric carcinoma specimens (observed group) and 20 normal gastric mucosa tissues (control group) by SP immunohistochemical method and in situ hybridization (ISH), respectively.HP infection was examined by Warthin-Starry method in observed group.Results The positive expression rate of hPOT1 protein was 84.91% (45/53) in observed group, higher than that in control group [30.00 % (6/20)] (P < 0.01).The positive expression rate of hPOT1 mRNA was 58.49 % (31/53) in observed group, higher than that in control group [10.00 % (2/20)] (P < 0.05).The positive co-expression rate of hPOT1 protein and mRNA was 56.60 % (30/53), both had positive relationship in gastric carcinoma (r =0.394, P < 0.05).The rate of HP infection in 53 cases of gastric carcinoma was 52.83 % (28/53).The positive expression rates of hPOTI protein and mRNA in observed group with HP infection were significantly higher than those in observed group without HP infection[protein: 96.43 % (27/28) vs 72.00 % (18/25), P <0.05;mRNA: 85.75 % (24/28) vs 28.00 % (7/25), P < 0.01].Conclusions hPOT1 may be associated with occurrence of gastric carcinoma.Combined detection of hPOT1 protein and mRNA can be used for the diagnosis of gastric carcinoma.HP infection may be associated with abnormal expression of hPOT1 in occurrence of gastric carcinoma.
8."Analysis on the management system and operation mechanism of Sanming's healthcare reform towards ""Tripartite-sector reform"""
Hong LE ; Siyu TAO ; Xiaoxu YIN ; Pengqian FANG
Chinese Journal of Hospital Administration 2017;33(4):247-251
Centering on the reform practice in Sanming featuring a synergistic reform in public health services,medical insurance and medicine production-circulation (Tripartite-sector reform below),this paper focused on the top-level design of the management system in such a reform and its synergistic operation mechanism.The authors probed into the main reasons for its grounding-breaking success and challenges,to pave way for their discussions on the reproducibility and sustainability of the reform.
9.Analysis of governmental responsibilities in health protection as inspired by the model of Sanming's healthcare reform
Siyu TAO ; Hong LE ; A'hong HUANG ; Pengqian FANG ; Fang WANG ;
Chinese Journal of Hospital Administration 2017;33(4):252-254
Success of Sanming's heahhcare reform relies heavily on the government's dominant role.Based on this inspiration,the paper discussed the responsibilities expected of the government in health protection of the people as required by national strategy,public interests and market demands,and presented the corresponding responsibilities of the government in the protection,leadership,scrutiny and management for the sake of public health.In addition the paper recommended on policies to make up for the absence and dislocation of governmental responsibilities,including all-out efforts for legislations in health protection,greater government subsidy for health protection,development of a comprehensive supervision system,and establishment of entities accountable for people's health in general.
10.Angiography Features and Clinical Significance of Pelvic Tumor
Junfang LIU ; Zhiyong WANG ; Jinxiang HU ; Tao LE ; Chunyan CAI
Journal of Practical Radiology 1996;0(04):-
Objective To study angiography features and clinical significance of "multiple tumor feeding embolization".Methods Twelve patients with pelvic tumor were reviewed retrospectively.The lesions included fibrosarcoma(n=1),chondrosarcoma(n=2),osteosarcoma(n=2) and metastatic tumor(n=7).Results Angiography features were:(1)multiple origin and branch of tumor-feeding vessels.(2)large vascular mass with dense tumor stain.(3)larger size of tumor stain comparing with that of bone destraction.After treatment,symptom relief and tumor shrink were obviously using"the multiple tumor-feeding embolization".Conclusion Angiography features of pelvic tumor are great value in guiding the clinical therapy.